In vivo mapping of a DNA adduct at nucleotide resolution: detection of pyrimidine (6-4) pyrimidone photoproducts by ligation-mediated polymerase chain reaction.

DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall

1985 • 1,233 citations

DNA METHYLATION AND GENE ACTIVITY

1983 • 1,115 citations

In Vivo Footprinting of a Muscle Specific Enhancer by Ligation Mediated PCR

1989 • 972 citations

THE BIOLOGY OF THE (6–4) PHOTOPRODUCT

1989 • 604 citations

Preferential DNA repair of an active gene in human cells.

1986 • 455 citations

Genomic Sequencing and Methylation Analysis by Ligation Mediated PCR

1989 • 408 citations

UV-induced mutation hotspots occur at DNA damage hotspots

1982 • 397 citations

THE RELATIVE CYTOTOXICITY OF(6–4) PHOTOPRODUCTS AND CYCLOBUTANE DIMERS IN MAMMALIAN CELLS*

1988 • 353 citations

Cytosine methylation and the fate of CpG dinucleotides in vertebrate genomes

1989 • 336 citations

Cleavage of pyrimidine dimers in specific DNA sequences by a pyrimidine dimer DNA-glycosylase of M. luteus

1980 • 307 citations

Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability.

1990 • 264 citations

Distribution of UV light-induced damage in a defined sequence of human DNA: detection of alkaline-sensitive lesions at pyrimidine nucleoside-cytidine sequences.

1981 • 252 citations

In vivo footprint and methylation analysis by PCR-aided genomic sequencing: comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1.

1990 • 250 citations

Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells.

1987 • 242 citations

UV MUTAGENIC PHOTOPRODUCTS IN Escherichia coli AND HUMAN CELLS: A MOLECULAR GENETICS PERSPECTIVE ON HUMAN SKIN CANCER*

1988 • 236 citations

The specificity of UV-induced mutations at an endogenous locus in mammalian cells.

1987 • 216 citations

Use of light for footprinting DNA in vivo

1984 • 181 citations

Purification of Escherichia coli DNA photolyase.

1984 • 170 citations

Alkaline lability of fluorescent photoproducts produced in ultraviolet light-irradiated DNA.

1982 • 164 citations

den V gene of bacteriophage T4 determines a DNA glycosylase specific for pyrimidine dimers in DNA

1980 • 126 citations

QUANTITATIVE CONVERSION OF THE (6–4) PHOTOPRODUCT OF TpdC TO ITS DEWAR VALENCE ISOMER UPON EXPOSURE TO SIMULATED SUNLIGHT

1990 • 117 citations

The C-C (6-4) UV photoproduct is mutagenic in Escherichia coli.

1986 • 101 citations

Preferential DNA repair of (6-4) photoproducts in the dihydrofolate reductase gene of Chinese hamster ovary cells

1989 • 94 citations

A constitutive damage-specific DNA-binding protein is synthesized at higher levels in UV-irradiated primate cells.

1990 • 92 citations

Rapid repair kinetics of pyrimidine(6–4)pyrimidone photoproducts in human cells are due to excision rather than conformational change

1990 • 92 citations

Demethylation of specific sites in the 5' region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expression.

1988 • 90 citations

The role of the (6−4) photoproduct in ultraviolet light-induced transition mutations in E. coli

1986 • 73 citations

Repair of DNA‐containing pyrimidine dimers

1988 • 66 citations

General method for quantifying base adducts in specific mammalian genes.

1988 • 63 citations

DNA methylation and cell memory

1989 • 50 citations

Demethylation enhances removal of pyrimidine dimers from the overall genome and from specific DNA sequences in Chinese hamster ovary cells.

1989 • 47 citations

Ligation-mediated PCR improves the sensitivity of methylation analysis by restriction enzymes and detection of specific DNA strand breaks

1990 • 46 citations

A 2-deoxyribonolactone-containing nucleotide: isolation and characterization of the alkali-sensitive photoproduct of the trideoxyribonucleotide d(ApCpA)

1989 • 36 citations

Demethylation of Specific Sites in the 5′ Region of the Inactive X-Linked Human Phosphoglycerate Kinase Gene Correlates with the Appearance of Nuclease Sensitivity and Gene Expression

1988 • 33 citations

Respective roles of pyrimidine dimer and pyrimidine (6-4) pyrimidone photoproducts in UV mutagenesis of simian virus 40 DNA in mammalian cells

1989 • 26 citations

Demethylation Enhances Removal of Pyrimidine Dimers from the Overall Genome and from Specific DNA Sequences in Chinese Hamster Ovary Cells

1989 • 16 citations