Long Term Correction of Bilirubin-UDP-glucuronosyltransferase Deficiency in Gunn Rats by Administration of a Recombinant Adenovirus during the Neonatal Period

Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression.

1995 • 599 citations

A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

1992 • 473 citations

Packaging capacity and stability of human adenovirus type 5 vectors

1993 • 457 citations

Adenovirus–mediated in vivo gene transfer and expression in normal rat liver

1992 • 451 citations

Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man.

1994 • 427 citations

The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer.

1994 • 217 citations

Drug-Responsive and Tissue-Specific Alternative Expression of Multiple First Exons in Rat UDP-Glucuronosyltransferase Family 1 (UGT1) Gene Complex

1995 • 137 citations

Use of Human Adenovirus-based Vectors for Antigen Expression in Animals

1989 • 122 citations

Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells.

1990 • 117 citations

A novel mechanism for achieving transgene persistence in vivo after somatic gene transfer into hepatocytes.

1992 • 92 citations

Bilirubin Mono- and diglucuronide formation by human liverIn vitro: Assay by high-pressure liquid chromatography

1981 • 63 citations

LONG-TERM SMALL-BOWEL GRAFT SURVIVAL INDUCED BY A SPONTANEOUSLY TOLERATED LIVER ALLOGRAFT IN INBRED RAT STRAINS

1992 • 49 citations

Mechanism of the lack of induction of UDP-glucuronosyltransferase activity in Gunn rats by 3-methylcholanthrene. Identification of a truncated enzyme.

1990 • 43 citations

Characterization of cytotoxic cells in mice rendered neonatally tolerant of MHC alloantigens: evidence for repertoire modification.

1987 • 18 citations

DIFFERENTIAL EXPRESSION OF HELPER VERSUS EFFECTOR ACTIVITY IN MICE RENDERED NEONATALLY TOLERANT OF CLASS II MHC ANTIGENS

1989 • 13 citations

Cellular mechanisms that maintain neonatally-induced tolerance of class II alloantigens. Evidence that factor-mediated suppression silences cytotoxic T cell activity.

1994 • 13 citations

Cellular mechanisms that maintain neonatally-induced tolerance of class II alloantigens. Evidence that precursor cytotoxic T cells are present but silenced.

1994 • 8 citations

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