Interleukin 6 is an autocrine growth factor for mesangial cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

1987 • 1,667 citations

Production of hybridoma growth factor by human monocytes

1987 • 1,133 citations

Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors.

1987 • 847 citations

The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells.

1988 • 791 citations

Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas.

1986 • 701 citations

Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).

1985 • 679 citations

IgG1 plasmacytosis in interleukin 6 transgenic mice.

1989 • 597 citations

IL-1 stimulates IL-6 production in endothelial cells.

1989 • 541 citations

Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells.

1989 • 470 citations

A ROLE OF POLYMORPHONUCLEAR LEUKOCYTES AND COMPLEMENT IN NEPHROTOXIC NEPHRITIS

1965 • 421 citations

Involvement of IL-6 in mesangial proliferative glomerulonephritis.

1989 • 415 citations

B-cell-stimulatory factor 2 (beta 2 interferon) functions as a second signal for interleukin 2 production by mature murine T cells.

1987 • 357 citations

Two interferon mRNAs in human fibroblasts: in vitro translation and Escherichia coli cloning studies.

1980 • 341 citations

T cell growth and differentiation induced by interleukin-HP1/IL-6, the murine hybridoma/plasmacytoma growth factor.

1988 • 244 citations

Regulation of interleukin-6 expression in cultured human blood monocytes and monocyte-derived macrophages

1988 • 234 citations

Stimulation of rat mesangial cell proliferation by macrophage interleukin 1.

1983 • 219 citations

Accessory cell dependence of lectin‐induced proliferation of mouse T lymphocytes

1977 • 206 citations

IFN-beta 2, B cell differentiation factor 2, or hybridoma growth factor (IL-6) is expressed and released by human epidermal cells and epidermoid carcinoma cell lines.

1989 • 205 citations

Bacterial lipopolysaccharide (endotoxin) enhances expression and secretion of beta 2 interferon by human fibroblasts.

1987 • 199 citations

Improved methods for culturing rat glomerular cells

1984 • 199 citations

Structure of the Rat Interleukin 6 Gene and Its Expression in Macrophage-derived Cells

1989 • 199 citations

Mesangial cells express PDGF mRNAs and proliferate in response to PDGF

1988 • 191 citations

Transcriptional regulation of the interferon-beta 2/B cell differentiation factor BSF-2/hepatocyte-stimulating factor gene in human fibroblasts by other cytokines.

1988 • 183 citations

Growth inhibition of human breast carcinoma and leukemia/lymphoma cell lines by recombinant interferon-beta 2.

1988 • 182 citations

Intraglomerular T cells and monocytes in nephritis: Study with monoclonal antibodies

1987 • 181 citations

Synergism of BSF-2/interleukin 6 and interleukin 3 on development of multipotential hemopoietic progenitors in serum-free culture.

1988 • 165 citations

Interleukin 1 and the glomerular mesangium. I. Purification and characterization of a mesangial cell-derived autogrowth factor.

1986 • 164 citations

T-cells and macrophages in rapidly progressive glomerulonephritis: Clinicopathologic correlations

1987 • 159 citations

Synergistic activation of human t cells by interleukin 1 and interleukin 6

1988 • 153 citations

Purification and NH2-terminal sequence of a plasmacytoma growth factor derived from the murine macrophage cell line P388D1.

1987 • 145 citations

T lymphocyte participation in antibody-induced experimental glomerulonephritis

1985 • 138 citations

Activation of glomerular mesangial cells by the terminal membrane attack complex of complement.

1987 • 135 citations

Regulation of the acute phase and immune responses in viral disease. Enhanced expression of the beta 2-interferon/hepatocyte-stimulating factor/interleukin 6 gene in virus-infected human fibroblasts.

1988 • 131 citations

Interferon-beta 2/interleukin 6 is a co-stimulant for human T lymphocytes.

1988 • 125 citations

Secretory proteins induced in human fibroblasts under conditions used for the production of interferon beta.

1982 • 125 citations

Production of platelet-derived growth factorlike protein by rat mesangial cells in culture.

1987 • 110 citations

Cell culture approaches to the analysis of glomerular inflammation

1986 • 106 citations

IL-6 and IL-1 synergize to stimulate IL-2 production and proliferation of peripheral T cells.

1989 • 102 citations

Distinct roles of IL-1 and IL-6 in human T cell activation.

1989 • 95 citations

Mesangium and glomerular disease.

1985 • 80 citations

Immortalization of BGDF (BCGF II)- and BCDF-producing T cells by human T cell leukemia virus (HTLV) and characterization of human BGDF (BCGF II).

1985 • 73 citations

Production of platelet-activating factor in glomeruli and cultured glomerular mesangial cells

1986 • 68 citations

Identification of IL-6 as a T cell-derived factor that enhances the proliferative response of thymocytes to IL-4 and phorbol myristate acetate.

1988 • 64 citations

Transfer of experimental glomerulonephritis in chickens by mononuclear cells

1988 • 63 citations

Insulinlike growth factor-1 is a progression factor for human mesangial cells.

1989 • 62 citations

The temporal relationship between glomerular cell proliferation and monocyte infiltration in Experimental glomerulonephritis

1981 • 46 citations

Cyclosporin A inhibits acute serum sickness nephritis in rabbits.

1983 • 41 citations

Characterization of a keratinocyte-derived T cell growth factor distinct from interleukin 2 and B cell stimulatory factor 1.

1987 • 22 citations

Rat mesangial cells produce granulocyte-macrophage colony-stimulating factor

1989 • 20 citations