Agouti Antagonism of Melanocortin-4 Receptor: Greater Effect with Desacetyl-α-Melanocyte-Stimulating Hormone (MSH) than withα -MSH

Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice

1997 • 2,992 citations

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

1997 • 1,891 citations

Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein

1997 • 1,835 citations

The Cloning of a Family of Genes That Encode the Melanocortin Receptors

1992 • 1,616 citations

Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.

1994 • 1,059 citations

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

1994 • 1,055 citations

Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function

1993 • 873 citations

Molecular cloning, expression, and gene localization of a fourth melanocortin receptor

1993 • 844 citations

Molecular characterization of the mouse agouti locus

1992 • 791 citations

Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system.

1993 • 719 citations

Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain

1994 • 703 citations

Molecular cloning of a novel melanocortin receptor.

1993 • 683 citations

The Coat Colors of Mice

1979 • 646 citations

Exocrine Gland Dysfunction in MC5-R-Deficient Mice: Evidence for Coordinated Regulation of Exocrine Gland Function by Melanocortin Peptides

1997 • 477 citations

MECHANISM OF THE DEVELOPMENT OF OBESITY IN ANIMALS WITH HYPOTHALAMIC LESIONS

1946 • 471 citations

Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation.

1993 • 428 citations

The coat colours of mice. A model for mammalian gene action and interaction.

1979 • 401 citations

ACTH-(1–24) and α-MSH antagonize feeding behavior stimulated by kappa opiate agonists

1986 • 240 citations

Molecular Cloning of a Mouse Melanocortin 5 Receptor Gene Widely Expressed in Peripheral Tissues

1994 • 212 citations

Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line.

1996 • 196 citations

Central and peripheral endorphins: Basic and clinical aspects

1983 • 185 citations

Acetylation alters the feeding response to MSH and beta-endorphin

1989 • 163 citations

Linkage and Association Studies between the Melanocortin Receptors 4 and 5 Genes and Obesity-Related Phenotypes in the Québec Family Study

1997 • 162 citations

Molecular structure and chromosomal mapping of the human homolog of the agouti gene.

1994 • 160 citations

[2] Cellular responsiveness to hormones and neutrotransmitters: Conversion of [3H]Adenine to [3H]cAMP in cell monolayers, cell suspensions, and tissue slices

1991 • 124 citations

Agouti structure and function: characterization of a potent .alpha.-melanocyte stimulating hormone receptor antagonist

1995 • 104 citations

N -Acetylation Regulates the Behavioral Activity of α-Melanotropin in a Multineurotransmitter Neuron

1982 • 93 citations

Agouti Antagonism of Melanocortin Binding and Action in the B16F10 Murine Melanoma Cell Line

1995 • 73 citations

Effects of MSH on food intake, body weight and coat color of the yellow obese mouse

1989 • 67 citations

1989 McCollum Award lecture. Genetic and hypothalamic mechanisms for obesity--finding the needle in the haystack

1989 • 39 citations

Effects of a potent melanocortin agonist on the diabetic/obese phenotype in yellow mice

1998 • 19 citations

Prenatal processing of pro-opiomelanocortin in the brain and pituitary of mouse embryos

1991 • 18 citations

N-Acetyltransferase mechanism for α-melanocyte stimulating hormone regulation in rat ageing

1995 • 12 citations

Melanocortins and opioids modulate early postnatal growth in rats

1995 • 10 citations

Changes in Dopaminergic Control of Circulating Melanocyte-Stimulating Hormone-Related Peptides at Puberty

1995 • 8 citations

Pituitary Changes of Desacetyl-α-Melanocyte-Stimulating Hormone throughout Development

1988 • 7 citations

Des-acetyl-α-MSH and not α-MSH is the major form of α-MSH in amniotic fluid

1988 • 6 citations