Small GTP-Binding Protein Rac Is an Essential Mediator of Vascular Endothelial Growth Factor-Induced Endothelial Fenestrations and Vascular Permeability

Angiogenesis in cancer and other diseases

2000 • 8,734 citations

The Biology of Vascular Endothelial Growth Factor

1997 • 4,359 citations

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1996 • 4,143 citations

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

1983 • 3,942 citations

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1996 • 3,664 citations

Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor

1998 • 2,440 citations

In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse

1999 • 2,410 citations

Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

2001 • 1,874 citations

Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

2001 • 1,707 citations

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions

2001 • 1,640 citations

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation

1992 • 1,103 citations

Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor

1995 • 1,026 citations

Clinical applications of angiogenic growth factors and their inhibitors

1999 • 1,017 citations

Role of Akt Signaling in Vascular Homeostasis and Angiogenesis

2002 • 981 citations

Vascular permeability factor (VPF, VEGF) in tumor biology

1993 • 839 citations

Vascular Permeability Factor/Vascular Endothelial Growth Factor and the Significance of Microvascular Hyperpermeability in Angiogenesis

1999 • 752 citations

Vascular endothelial growth factor enhances atherosclerotic plaque progression

2001 • 711 citations

Matrix-dependent Tiam1/Rac Signaling in Epithelial Cells Promotes Either Cell–Cell Adhesion or Cell Migration and Is Regulated by Phosphatidylinositol 3-Kinase

1998 • 667 citations

Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

2001 • 666 citations

Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth.

1996 • 567 citations

Vascular endothelial growth factor C induces angiogenesis in vivo

1998 • 558 citations

VEGFs, receptors and angiogenesis

1999 • 523 citations

A PtdInsP3- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

2002 • 522 citations

Vascular Endothelial Cell Growth Factor Promotes Tyrosine Phosphorylation of Mediators of Signal Transduction That Contain SH2 Domains

1995 • 480 citations

Neovasculature induced by vascular endothelial growth factor is fenestrated.

1997 • 441 citations

Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF

2001 • 435 citations

Quantitative angiogenesis assays: Progress and problems

1997 • 386 citations

VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic β cell carcinogenesis

2002 • 372 citations

Neuropilin-1 Is a Placenta Growth Factor-2 Receptor

1998 • 344 citations

Heterodimers of Placenta Growth Factor/Vascular Endothelial Growth Factor

1996 • 295 citations

c- fos -induced growth factor/vascular endothelial growth factor D induces angiogenesis in vivo and in vitro

1999 • 271 citations

Angiogenesis Therapy

2001 • 233 citations

Placenta Growth Factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers

2002 • 195 citations

Angiogenesis in the Mouse Cornea

1979 • 188 citations

Rac Regulates Endothelial Morphogenesis and Capillary Assembly

2002 • 160 citations

VPF/VEGF and the angiogenic response

2000 • 150 citations

Lipid Products of Phosphoinositide 3-Kinase Interact with Rac1 GTPase and Stimulate GDP Dissociation

1998 • 103 citations

Divergence of Angiogenic and Vascular Permeability Signaling by VEGF

2002 • 64 citations

Morphological and cytochemical aspects of capillary permeability

2002 • 54 citations

Transmyocardial Laser Revascularization Remodels the Intrinsic Cardiac Nervous System in a Chronic Setting

2001 • 36 citations