Structural Topology of Transmembrane Helix 10 in the Lactose Permease of Escherichia coli

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Experiments in molecular genetics

1972 • 28,260 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

[32] Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

1983 • 1,093 citations

A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport

1993 • 939 citations

Intestinal Absorption of Sugars

1960 • 662 citations

Using mini-prep plasmid DNA for sequencing double stranded templates with Sequenase.

1988 • 552 citations

Sequence of the lactose permease gene

1980 • 501 citations

Mammalian and bacterial sugar transport proteins are homologous

1987 • 400 citations

Membrane transport proteins: implications of sequence comparisons

1992 • 330 citations

The gradient hypothesis and other models of carrier-mediated active transport

2005 • 327 citations

Structure of the lac carrier protein of Escherichia coli.

1983 • 299 citations

Lactose Carrier Protein of Escherichia coli Structure and Expression of Plasmids Carrying the Y Gene of the lac Operon

1980 • 262 citations

Lactose transport coupled to proton movements in escherichia coli

1970 • 251 citations

lac permease of Escherichia coli: topology and sequence elements promoting membrane insertion.

1990 • 248 citations

Depolarization of the Plasma Membrane of Neurospora During Active Transport of Glucose: Evidence for a Proton-Dependent Cotransport System

1974 • 226 citations

Amplification of the lactose carrier protein in Escherichia coli using a plasmid vector

1978 • 161 citations

Proton-linked sugar transport systems in bacteria

1990 • 154 citations

Proton‐coupled hexose transport in Chlorella vulgaris

1973 • 141 citations

The interaction between aspartic acid 237 and lysine 358 in the lactose carrier of Escherichia coli

1991 • 117 citations

Stoicheiometrical proton and potassium ion movements accompanying the absorption of amino acids by the yeast Saccharomyces carlsbergensis

1971 • 111 citations

Evidence for a proton/sugar symport in the yeast Rhodotorula gracilis (glutinis)

1978 • 107 citations

Frameshift Mutations in the Lactose Operon of E. coli

1966 • 97 citations

Structural features of the uniporter/symporter/antiporter superfamily

1995 • 97 citations

Cysteine scanning mutagenesis of putative transmembrane helices IX and X in the lactose permease of Escherichia coli

1993 • 87 citations

Functional roles of Glu-269 and Glu-325 within the lactose permease of Escherichia coli.

1994 • 84 citations

Isolation and nucleotide sequencing of lactose carrier mutants that transport maltose.

1985 • 76 citations

β-galactoside transport in E. coli: a functional dissection of lac permease

1990 • 70 citations

The lactose permease of Escherichia coli

1990 • 67 citations

Isolation and Characterization of Lactose Permease Mutants with an Enhanced Recognition of Maltose and Diminished Recognition of Cellobiose

1989 • 65 citations

Engineering a Metal Binding Site within a Polytopic Membrane Protein, the Lactose Permease of Escherichia coli

1995 • 61 citations

Information content of amino acid residues in putative helix VIII of the lac permease from Escherichia coli

1990 • 41 citations

The lac permease of Escherichia coli: site-directed mutagenesis studies on the mechanism of β-galactoside/H+ symport

1990 • 40 citations

Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 2. Proximity of helix IX (Arg302) with helix X (His322 and Glu325)

1995 • 38 citations

Isolation and Characterization of Thiodigalactoside-resistant Mutants of the Lactose Permease Which Possess an Enhanced Recognition for Maltose

1989 • 33 citations

Cell membranes: Methods and reviews

1984 • 20 citations