Generation and functional characterization of human dendritic cells derived from CD34⁺ cells mobilized into peripheral blood: comparison with bone marrow CD34⁺ cells

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

1996 • 1,854 citations

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

1992 • 1,608 citations

Differentiation and proliferation of hematopoietic stem cells

1993 • 1,417 citations

Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens

1994 • 1,185 citations

Generation of mature dendritic cells from human blood An improved method with special regard to clinical applicability

1996 • 1,138 citations

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

1995 • 1,097 citations

Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo.

1996 • 922 citations

Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity.

1996 • 746 citations

Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood

1996 • 696 citations

Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ.

1990 • 670 citations

Randomised trial of filgrastim-mobilised peripheral blood progenitor cell transplantation versus autologous bone-marrow transplantation in lymphoma patients

1996 • 633 citations

Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo.

1996 • 561 citations

Interactions of tumor necrosis factor with granulocyte-macrophage colony-stimulating factor and other cytokines in the regulation of dendritic cell growth in vitro from early bipotent CD34+ progenitors in human bone marrow.

1992 • 452 citations

Expansion of immunostimulatory dendritic cells among the myeloid progeny of human CD34+ bone marrow precursors cultured with c-kit ligand, granulocyte-macrophage colony-stimulating factor, and TNF-alpha.

1995 • 350 citations

Induction of antitumor immunity using bone marrow-generated dendritic cells.

1996 • 323 citations

Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo

1994 • 300 citations

Identification of dendritic cell colony-forming units among normal human CD34+ bone marrow progenitors that are expanded by c-kit-ligand and yield pure dendritic cell colonies in the presence of granulocyte/macrophage colony-stimulating factor and tumor necrosis factor alpha.

1995 • 296 citations

Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells.

1994 • 276 citations

Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donor

1995 • 269 citations

Generation of human dendritic cells/Langerhans cells from circulating CD34+ hematopoietic progenitor cells

1996 • 259 citations

Massive ex vivo generation of functional dendritic cells from mobilized CD34+ blood progenitors for anticancer therapy.

1995 • 237 citations

Retroviral transduction of human dendritic cells with a tumor-associated antigen gene.

1996 • 218 citations

Dendritic cells stimulate primary human cytolytic lymphocyte responses in the absence of CD4+ helper T cells.

1990 • 210 citations

Concomitant mobilization of plasma cells and hematopoietic progenitors into peripheral blood of multiple myeloma patients: positive selection and transplantation of enriched CD34+ cells to remove circulating tumor cells

1996 • 184 citations

Dendritic cells and immune-based therapies.

1996 • 180 citations

Human dendritic cell differentiation pathway from CD34+ hematopoietic precursor cells

1996 • 175 citations

Generation of antigen-specific CD8+ CTLs from naive precursors.

1994 • 143 citations

Dendritic cells are the most efficient in presenting endogenous naturally processed self-epitopes to class II-restricted T cells.

1995 • 125 citations

Cycling Status of CD34+ Cells Mobilized Into Peripheral Blood of Healthy Donors by Recombinant Human Granulocyte Colony-Stimulating Factor

1997 • 115 citations

THE DENDRITIC CELL LINEAGE IN HAEMOPOIESIS

1997 • 54 citations

Generation of antigen‐presenting cells for soluble protein antigens ex vivo from peripheral blood CD34⁺ hematopoietic progenitor cells in cancer patients

1996 • 43 citations

Alloantigen presenting function of normal human CD34+ hematopoietic cells

1996 • 40 citations

In vitro expansion and characterization of dendritic cells derived from human bone marrow CD34+ cells.

1996 • 20 citations