Enhancer competition between H19 and Igf 2 does not mediate their imprinting

Role for DNA methylation in genomic imprinting

1994 • 1,695 citations

The product of the H19 gene may function as an RNA.

1990 • 1,066 citations

Disruption of imprinting caused by deletion of the H19 gene region in mice

1995 • 765 citations

Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2

1998 • 641 citations

GENOMIC IMPRINTING IN MAMMALS

1997 • 641 citations

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal

1993 • 602 citations

Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region

1994 • 430 citations

An enhancer deletion affects both H19 and Igf2 expression.

1995 • 398 citations

The gene family encoding the mouse ribosomal protein L32 contains a uniquely expressed intron-containing gene and an unmutated processed gene

1984 • 381 citations

The Product of the H19 Gene May Function as an RNA

1990 • 370 citations

Zp3–cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line

1997 • 359 citations

The ontogeny of allele-specific methylation associated with imprinted genes in the mouse.

1993 • 345 citations

A 5′ 2-Kilobase-Pair Region of the Imprinted Mouse H19 Gene Exhibits Exclusive Paternal Methylation throughout Development

1997 • 341 citations

Intergenic transcription and transinduction of the human β-globin locus

1997 • 334 citations

The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo

1991 • 312 citations

Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes

1994 • 277 citations

Biallelic expression of imprinted genes in the mouse germ line: implications for erasure, establishment, and mechanisms of genomic imprinting.

1995 • 263 citations

Targeted insertion of exogenous DNA into the eukaryotic genome by the Cre recombinase.

1990 • 253 citations

Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element.

1997 • 243 citations

Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex.

1996 • 237 citations

Gene structure, DNA methylation, and imprinted expression of the human SNRPN gene.

1996 • 234 citations

Pattern of the insulin-like growth factor II gene expression during early mouse embryogenesis

1990 • 228 citations

The role of insulator elements in defining domains of gene expression

1997 • 217 citations

Ectopic expression of the H19 gene in mice causes prenatal lethality.

1991 • 178 citations

Imprinting mechanisms in mammals

1998 • 173 citations

Location of enhancers is essential for the imprinting of H19 and Igf2 genes

1998 • 126 citations

Loss of the maternal H19 gene induces changes in Igf 2 methylation in both cis and trans

1997 • 105 citations

Igf2 imprinting does not require its own DNA methylation or H19 RNA

1998 • 101 citations

Chromatin conformation of the H19 epigenetic mark

1998 • 76 citations

Characterization of Novel Parent-Specific Epigenetic Modifications Upstream of the Imprinted Mouse H19Gene

1998 • 45 citations

Chromatin boundaries: Punctuating the genome

1998 • 43 citations