CD4+ cells treated with DNA methylation inhibitors induce autologous B cell differentiation

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

The isolation and characterization of the human suppressor inducer T cell subset.

1985 • 860 citations

Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).

1985 • 679 citations

Evidence for impaired t cell dna methylation in systemic lupus erythematosus and rheumatoid arthritis

1990 • 546 citations

Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity.

1988 • 413 citations

Spontaneous release of a factor with properties of T cell growth factor from a continuous line of primate tumor T cells.

1981 • 368 citations

Profiles of Antinuclear Antibodies in Systemic Rheumatic Diseases

1975 • 365 citations

A systemic lupus erythematosus (SLE)‐like disease in mice induced by abnormal T‐B cell cooperation. Preferential formation of autoantibodies characteristic of SLE

1982 • 267 citations

Failure of autologous mixed lymphocyte reactions between T and non-T cells in patients with systemic lupus erythematosus.

1978 • 236 citations

Cloning of cDNA for human T-cell replacing factor (interieukin-5) and comparison with the murine homologue

1986 • 205 citations

Increased spontaneous activity of antibody‐forming cells in the peripheral blood of patients with active sle

1977 • 197 citations

The Autologous Mixed-Lymphocyte Reaction

1981 • 181 citations

Correlation of T and B cell activities in vitro and serum IL-2 levels in systemic lupus erythematosus.

1988 • 162 citations

Effect of an inhibitor of DNA methylation on T cells. II. 5-azacytidine induces self-reactivity in antigen-specific T4+ cells

1986 • 149 citations

The cellular basis of the impaired autologous mixed lymphocyte reaction in patients with systemic lupus erythematosus.

1979 • 143 citations

Allosuppressor- and allohelper-T cells in acute and chronic graft-vs.-host (GVH) disease. III. Different Lyt subsets of donor T cells induce different pathological syndromes.

1983 • 135 citations

Induction of suppression following autologous mixed lymphocyte reaction; role of a novel 2H4 antigen

1987 • 111 citations

Polyclonally triggered B cells in the peripheral blood and bone marrow of normal individuals and in patients with systemic lupus erythematosus and primary sjögren's syndrome

1981 • 106 citations

Anti-histone antibodies in idiopathic and drug-induced lupus recognize distinct intrahistone regions.

1987 • 101 citations

Drug-induced Lupus: Clinical and Serological Studies

1982 • 95 citations

Immunoregulatory activities of autoreactive T cells: an I-A-specific T cell clone mediates both help and suppression of antibody responses.

1984 • 87 citations

Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells

1986 • 83 citations

Responder cells in the human autologous mixed lymphocyte reaction.

1981 • 74 citations

Two types of Ia-positive T cells. Synthesis and exchange of Ia antigens.

1980 • 73 citations

A monoclonal antibody that blocks class II histocompatibility-related immune interactions

1984 • 70 citations

Autoimmunization in murine graft-vs-host disease. I. Selective production of antibodies to histones and DNA.

1985 • 67 citations

Quantitative defect of CD4+2H4+ cells in systemic lupus erythematosus and sjögren'S syndrome

1987 • 65 citations

Studies of rheumatoid synovial fluid lymphocytes

1983 • 60 citations

IgG antibodies to the histone complex H2A-H2B characterize procainamide-induced lupus

1985 • 59 citations

Studies of immune functions of patients with systemic lupus erythematosus

1979 • 57 citations

Procainamide‐Induced Lupus Erythematosus‐like Syndrome in Relation to Acetylator Phenotype and Plasma Levels of Procainamide

1979 • 56 citations

Frequency of anti-DNA antibody producing cells from normals and patients with systemic lupus erythematosus

1983 • 56 citations

Surface molecules involved in self-recognition and T cell activation in the autologous mixed lymphocyte reaction.

1984 • 55 citations

Autoantigenic histone epitopes: a comparison between procainamide‐ and hydralazine‐induced lupus

1987 • 47 citations

Effect of an inhibitor of DNA methylation on T cells. I. 5-Azacytidine induces T4 expression on T8+ T cells.

1986 • 46 citations

Generation of antigen receptor-specific suppressor T cell clones in man.

1986 • 46 citations

Increased immunoglobulin response to γ-interferon by lymphocytes from patients with systemic lupus erythematosus

1988 • 38 citations

Procainamide‐lymphocyte reactions. a possible explanation for drug‐induced autoimmunity

1981 • 35 citations

A self‐Ia reactive T cell clone directly stimulates every hundredth B cell and helps antigen‐specific B cell responses

1985 • 33 citations

Class II major histocompatibility antigens and the etiology of systemic lupus erythematosus

1983 • 31 citations

N‐acetylprocainamide is a less potent inducer of t cell autoreactivity than procainamide

1988 • 30 citations

Studies of autologous mixed lymphocyte reactions in patients with systemic lupus erythematosus

1983 • 18 citations

The autologous mixed lymphocyte reaction

1982 • 13 citations

Spontaneous in vitro production of anti‐DNA and anti‐RNA by systemic lupus erythematosus and normal peripheral blood mononuclear cells

1985 • 11 citations

B cell activation in patients with active procainamide induced lupus.

1988 • 9 citations