A monoclonal antibody that blocks class II histocompatibility-related immune interactions

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

HISTOCOMPATIBILITY TESTING, 1972

1974 • 1,267 citations

Two populations of Ia-like molecules on a human B cell line.

1980 • 1,112 citations

Separation of functional subsets of human T cells by a monoclonal antibody.

1979 • 1,062 citations

A monoclonal antibody to human acute lymphoblastic leukaemia antigen

1980 • 748 citations

Monoclonal Antibodies for Analysis of the HLA System

1979 • 745 citations

Clonal analysis of human cytotoxic T lymphocytes: T4+ and T8+ effector T cells recognize products of different major histocompatibility complex regions.

1982 • 600 citations

Ia determinants on human T-cell subsets defined by monoclonal antibody. Activation stimuli required for expression.

1979 • 592 citations

Antigens on human monocytes identified by monoclonal antibodies.

1981 • 583 citations

Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor

1983 • 464 citations

Peripheral human T cells sensitized in mixed leukocyte culture synthesize and express Ia-like antigens.

1978 • 374 citations

Immunological dissection of human Ia molecules.

1978 • 263 citations

Monoclonal antibodies defining serologically distinct HLA-D/DR related Ia-like antigens in man

1981 • 247 citations

Analysis of HLA-D region-associated molecules with monoclonal antibody.

1979 • 246 citations

Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+.

1982 • 237 citations

Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen

1981 • 203 citations

Biochemical characterization of a second family of human Ia molecules, HLA-DS, equivalent to murine I-A subregion molecules.

1982 • 197 citations

Differential expression and serologically distinct subpopulations of human Ia antigens detected with monoclonal antibodies to Ia alpha and beta chains

1982 • 183 citations

Analysis of Antigenic Determinants on Human Monocytes and Macrophages

1982 • 179 citations

Human Ia molecules carrying DC1 determinants differ in both α- and β-subunits from Ia molecules carrying DR determinants

1981 • 169 citations

Family studies define a new histocompatibility locus, SB, between HLA-DR and GLO

1981 • 153 citations

Serologic and immunochemical characterization of the specificity of four monoclonal antibodies to distinct antigenic determinants expressed on subpopulations of human Ia-like antigens.

1981 • 152 citations

HLA‐D Restriction of the Macrophage‐Dependent Response of Immune Human T Lymphocytes to PPD in Vitro: Inhibition by Anti‐HLA‐DR Antisera

1978 • 151 citations

Subsets of human Ia-like molecules defined by monoclonal antibodies

1981 • 147 citations

HLA-A2 as a target for cell-mediated lympholysis: Evidence from immunoselected HLA-A2 negative mutant cell lines

1980 • 131 citations

The role of T cell differentiation markers in antigen-specific and lectin-dependent cellular cytotoxicity mediated by T8+ and T4+ human cytotoxic T cell clones directed at class I and class II MHC antigens.

1982 • 121 citations

Purification of immunologically functional subsets of human Ia-like antigens on a monoclonal antibody (Q5/13) immunoadsorbent.

1980 • 120 citations

Studies with B-Cell Allo- and Hetero-Antisera: Parallel Reactivity and Special Properties

1976 • 120 citations

Structural Analysis of Differentiation Antigens Mol and Mo2 On Human Monocytes

1982 • 118 citations

Alpha and beta chains of SB and DR antigens are structurally distinct

1982 • 112 citations

Murine Monoclonal Antibodies against HLA Structures

1979 • 93 citations

Human T4+ and T8+ cytotoxic T lymphocyte clones directed at products of different class II major histocompatibility complex loci.

1983 • 87 citations

HLA-DR antigens render resting T cells sensitive to Interleukin-2 and induce production of the growth factor in the autologous mixed lymphocyte reaction

1981 • 85 citations

Human cytotoxic T cell clones directed at autologous virus-transformed targets: further evidence for linkage of genetic restriction to T4 and T8 surface glycoproteins.

1983 • 76 citations

HLA-D region-associated determinants serve as targets for human cell-mediated lysis.

1979 • 76 citations

A monoclonal antibody defining a lymphoma-associated antigen in man.

1980 • 69 citations

IL-2-mediated T cell proliferation in humans is blocked by a monoclonal antibody directed against monomorphic determinants of HLA-DR antigens.

1982 • 69 citations

In Vitro Primary Immunization of Human Peripheral Blood Lymphocytes to KLH: Evidence for HLA-D Region Restriction

1979 • 61 citations

Human DR (Ia-Like) Antigens: Biological and Molecular Profile

1978 • 59 citations

A monoclonal anti-DC1 antibody selectivity inhibits the generation of effector T cells mediating specific cytolytic activity.

1982 • 59 citations

Effect of anti-HLA antisera on macrophage-T-cell interactions.

1979 • 49 citations

Specific human B lymphocyte alloantigens linked to HL-A.

1975 • 46 citations

Distribution of antigenic determinants recognized by three monoclonal antibodies (Q2/70, Q5/6 and Q5/13) on human Ia-like alloantigens and on their subunits

1981 • 41 citations

CELL-MEDIATED LYMPHOCYTOTOXICITY DIRECTED AGAINST HLA-D GENE PRODUCTS

1979 • 41 citations

Participation of suppressor T cells in the immunosuppressive activity of a heteroantiserum to human Ia-like antigens (p23,30).

1980 • 40 citations

Allogeneic mixed lymphocyte reactions in humans: pretreatment of either the stimulator or the responder cell population with monoclonal anti-Ia antibodies leads to an inhibition of cell proliferation.

1981 • 39 citations

Robbit antisera to human B cell alloantigens: Effects on the mixed lymphocyte response

1977 • 36 citations

In Vitro Sensitization of Human T Lymphocytes to Hapten (TNP)-Conjugated and Non-treated Autologous Cells is Restricted by Self-HLA-D

1979 • 31 citations

Human macrophage-lymphocyte interaction in proliferation to soluble antigen

1980 • 28 citations

The role of p23,30-bearing human macrophages in antigen-induced T lymphocyte responses

1979 • 27 citations

Evidence that antisera that react with products of the human HLA-DR locus may block in vitro antigen-induced proliferation by inducing suppression.

1982 • 24 citations

Ia antigen on peripheral blood mononuclear leukocytes in man. I. Expression, biosynthesis, and function of HLA-DR antigen non-T cells.

1980 • 24 citations

A hybridoma antibody which reacts with human cells carrying the DRw4 tissue type. Evidence for heterogeneity of DRw4.

1980 • 22 citations

Role of Class I and Class II antigens in the allogenic stimulation: Class I and Class II recognition in allogenic stimulation; blocking of MLR by monoclonal antibodies and F(ab′)2 fragments

1983 • 22 citations

Inhibitory activity of antibodies to human Ia-like determinants: comparison of intact and pepsin-digested antibodies.

1983 • 21 citations

A rapid method for isolation of antigenically active human cell surface antigens associated with β2-microglobulin using a monoclonal antibody

1981 • 20 citations

A HYBRIDOMA ANTIBODY WHICH REACTS WITH HUMAN CELLS CARRYING THE DRw4 TISSUE TYPE EVIDENCE FOR HETEROGENEITY OF DRw4

1980 • 20 citations

Role of individual chains of HLA-DR antigens in activation of T cells induced by alloantigens

1981 • 20 citations

HLA-DR bouillabaisse

1983 • 20 citations

Serological, functional, and immunochemical characterization of a monoclonal antibody (MoAb Q2/70) to human Ia-like antigens

1980 • 17 citations

Antigen-specific human T lymphocyte clones: mechanisms of inhibition of proliferative responses by xenoantiserum to human nonpolymorphic HLA-DR antigens.

1982 • 16 citations

The role of HLA-DR determinants in monocyte-macrophage presentation of herpes simplex virus antigen to human T cells

1981 • 15 citations

Genetic Control of B‐Cell Alloantigens: Evidence for Gene(s) Linked to the HLA—A Locus

1978 • 14 citations

HLA-DR products are a subset of human Ia antigens

1983 • 14 citations

Effect of polyclonal and monoclonal HLA-DR xenoantibodies on xenogeneic mixed lymphocyte reactions

1980 • 14 citations

Monocyte function in mixed lymphocyte reactions

1980 • 13 citations

Human macrophage-lymphocyte interaction in proliferation to soluble antigen

1980 • 11 citations

In vitro primary immunization of human peripheral blood lymphocytes to KLH: evidence for HLA-D-region restriction.

1979 • 10 citations

Affinity and Inhibitory Capacity of T‐Cell Proliferation of Monoclonal Anti‐Ia Antibodies

1982 • 8 citations

Inhibition by Fab and Fab'2 monoclonal anti-Ia antibody fragments of T-lymphocyte proliferative responses.

1982 • 7 citations

Membrane expression and synthesis of p23,30 (HLA-DR antigen) by human peripheral blood monocytes.

1980 • 5 citations

The role of products of the human HLA-DR locus (Ia molecules) in in vitro M. leprae driven lymphoproliferation.

1983 • 2 citations