Inhibition of the hyperpolarization‐activated current (if) induced by acetylcholine in rabbit sino‐atrial node myocytes.

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

GTP-binding proteins couple cardiac muscarinic receptors to a K channel

1985 • 868 citations

How does adrenaline accelerate the heart?

1979 • 563 citations

Uncoupling of cardiac muscarinic and β-adrenergic receptors from ion channels by a guanine nucleotide analogue

1985 • 527 citations

Acetylcholine activation of single muscarinic K+ channels in isolated pacemaker cells of the mammalian heart

1983 • 471 citations

Properties of the hyperpolarizing‐activated current (if) in cells isolated from the rabbit sino‐atrial node.

1986 • 468 citations

Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells

1984 • 436 citations

Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.

1979 • 382 citations

VAGAL AND SYMPATHETIC EFFECTS ON THE PACEMAKER FIBERS IN THE SINUS VENOSUS OF THE HEART

1956 • 359 citations

A study of the ionic nature of the pace‐maker current in calf Purkinje fibres.

1981 • 346 citations

Opposite effects of cyclic GMP and cyclic AMP on Ca2+ current in single heart cells

1986 • 338 citations

Activation and attenuation of adenylate cyclase. The role of GTP-binding proteins as macromolecular messengers in receptor–cyclase coupling

1981 • 322 citations

On the mechanism of muscarinic inhibition of the cardiac Ca current

1986 • 283 citations

Characterization of single pacemaker channels in cardiac sino-atrial node cells

1986 • 262 citations

Changes in membrane currents in bullfrog atrium produced by acetylcholine.

1976 • 259 citations

Zum Mechanismus der Membranwirkung des Acetylcholin an der Herzmuskelfaser

1958 • 247 citations

Mechanism of action of acetylcholine on calcium current in single cells from frog ventricle.

1986 • 214 citations

Adrenaline: Mechanism of Action on the Pacemaker Potential in Cardiac Purkinje Fibers

1968 • 213 citations

Effects of Epinephrine on the Pacemaker Potassium Current of Cardiac Purkinje Fibers

1974 • 213 citations

Relaxation of the ACh-induced potassium current in the rabbit sinoatrial node cell

1978 • 200 citations

Muscarinic control of the hyperpolarization‐activated current (if) in rabbit sino‐atrial node myocytes.

1988 • 178 citations

Two Components of the Cardiac Action Potential

1969 • 154 citations

Attenuation of muscarinic cholinergic inhibition by islet-activating protein in the heart

1985 • 95 citations

The action of acetylcholine on background conductance in frog atrial trabeculae.

1978 • 91 citations

Acetylcholine inhibits activation of the cardiac hyperpolarizing-activated current,i f

1987 • 89 citations

The ionic currents underlying pacemaker activity in rabbit sino-atrial node: experimental results and computer simulations

1984 • 83 citations

On the kinetics of the potassium channel activated by acetylcholine in the S-A node of the rabbit heart

1980 • 79 citations

Effect of acetylcholine on membrane currents in guinea‐pig papillary muscle.

1980 • 77 citations

Pertussis toxin treatment blocks hyperpolarization by muscarinic agonists in chick atrium.

1985 • 71 citations

Effect of Vagal Stimulation on the Sinus Venosus of the Frog's Heart

1955 • 69 citations

Acetylcholine-induced potassium current fluctuations in the rabbit sino-atrial node

1979 • 64 citations

Barium-induced blockade of the inward rectifier in calf Purkinje fibres

1984 • 62 citations

Characterization of the acetylcholine‐induced potassium current in rabbit cardiac Purkinje fibres.

1986 • 61 citations

Changes by acetylcholine of membrane currents in rabbit cardiac Purkinje fibres.

1986 • 54 citations

Effect of acetylcholine on time-independent currents in sheep cardiac Purkinje fibers

1980 • 43 citations

Threshold effects of acetylcholine on primary pacemaker cells of the rabbit sino-atrial node

1985 • 37 citations

Cardiac calcium channels and their control by neurotransmitters and drugs

1985 • 36 citations

Acetylcholine and the mammalian 'slow inward' current : a computer investigation

1987 • 19 citations

Separation of current induced by potassium accumulation from acetylcholine-induced relaxation current in the rabbit S-A node

1980 • 19 citations