Interleukin-17 stimulates the expression of IκBα mRNA and the secretion of IL-6 and IL-8 in glioblastoma cell lines

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

1997 • 4,661 citations

NF-κB Controls Expression of Inhibitor IκBα: Evidence for an Inducible Autoregulatory Pathway

1993 • 1,141 citations

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation.

1993 • 1,047 citations

Human IL-17: a novel cytokine derived from T cells.

1995 • 1,014 citations

NF-kB: a crucial transcription factor for glial and neuronal cell function

1997 • 1,005 citations

Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor

1995 • 991 citations

IMF-κB and Rel: Participants in a Multiform Transcriptional Regulatory System

1993 • 967 citations

IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages.

1998 • 954 citations

IL-17 Stimulates the Production and Expression of Proinflammatory Cytokines, IL-β and TNF-α, by Human Macrophages

1998 • 810 citations

Neuroprotection by Aspirin and Sodium Salicylate Through Blockade of NF-κB Activation

1996 • 760 citations

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

1991 • 746 citations

Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha.

1993 • 639 citations

Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease

1997 • 611 citations

Interleukin-17 and Interferon-γ Synergize in the Enhancement of Proinflammatory Cytokine Production by Human Keratinocytes

1998 • 565 citations

Enhancing Effect of IL-17 on IL-1-Induced IL-6 and Leukemia Inhibitory Factor Production by Rheumatoid Arthritis Synoviocytes and Its Regulation by Th2 Cytokines

1998 • 451 citations

NF-κB and Rel Proteins in Innate Immunity

1995 • 435 citations

Interleukin-17-induced Gene Expression in Articular Chondrocytes Is Associated with Activation of Mitogen-activated Protein Kinases and NF-κB

1998 • 386 citations

Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family.

1993 • 331 citations

MOLECULAR CHARACTERIZATION OF THE HUMAN INTERLEUKIN (Il)-17 RECEPTOR

1997 • 282 citations

Mechanism of action of antiinflammatory drugs.

1998 • 266 citations

Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging

1998 • 246 citations

Interleukin-17

1998 • 201 citations

Induction of neuroprotective κB-dependent transcription by secreted forms of the Alzheimer's β-amyloid precursor

1996 • 192 citations

Strong nuclear factor-?B-DNA binding parallels cyclooxygenase-2 gene transcription in aging and in sporadic alzheimer's disease superior temporal lobe neocortex

1998 • 181 citations

Activation of nuclear factor-κB by β-amyloid peptides and interferon-γ in murine microglia

1997 • 113 citations

Alteration of transcription factors NF-κB and STAT1 in Alzheimer's disease brains

1997 • 112 citations

Interleukin-17 and its receptor.

1997 • 83 citations

Protein Kinase Inhibitors: Probes for the Functions of Protein Phosphorylation

1991 • 76 citations

Inflammatory Mediators in Alzheimer’s Disease

1997 • 21 citations