DNA sequence determinants of CAP-induced bending and protein binding affinity

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

The locus of sequence-directed and protein-induced DNA bending

1984 • 1,453 citations

Structure of the nucleosome core particle at 7 Å resolution

1984 • 1,028 citations

Sequence periodicities in chicken nucleosome core DNA

1986 • 930 citations

DNA bending and its relation to nucleosome positioning

1985 • 702 citations

Structure of catabolite gene activator protein at 2.9 Å resolution suggests binding to left-handed B-DNA

1981 • 651 citations

Cyclic AMP Receptor Protein: Role in Transcription Activation

1984 • 645 citations

Structure of the cro repressor from bacteriophage λ and its interaction with DNA

1981 • 545 citations

The operator-binding domain of λ repressor: structure and DNA recognition

1982 • 528 citations

Structure of the DNA-Eco RI Endonuclease Recognition Complex at 3 Å Resolution

1986 • 492 citations

Why does the electrophoretic mobility of DNA in gels vary with the length of the molecule?

1982 • 366 citations

Structure of the represser–operator complex of bacteriophage 434

1987 • 365 citations

The DNA binding domain and bending angle of E. coli CAP protein

1986 • 322 citations

Cassette mutagenesis: an efficient method for generation of multiple mutations at defined sites

1985 • 270 citations

DNA bend direction by phase sensitive detection

1987 • 252 citations

Mutations that alter the DNA sequence specificity of the catabolite gene activator protein of E. coli

1984 • 241 citations

Curved DN

1985 • 236 citations

Direct Evidence for DNA Bending at the Lambda Replication Origin

1987 • 233 citations

Mechanism of CRP-cAMP activation of lac operon transcription initiation activation of the P1 promoter

1984 • 228 citations

Visualization of the bent helix in kinetoplast DNA by electron microscopy

1986 • 226 citations

Effect of non-contacted bases on the affinity of 434 operator for 434 repressor and Cro

1987 • 217 citations

Importance of DNA stiffness in protein–DNA binding specificity

1987 • 204 citations

An altered DNA conformation in origin region I is a determinant for the binding of SV40 large T antigen

1986 • 200 citations

Principles of sequence-dependent flexure of DNA

1986 • 164 citations

Quantitative analysis of the relationship between nucleotide sequence and functional activity

1986 • 161 citations

On the different binding affinities of CRP at thelac, galandmalT promoter regions

1983 • 160 citations

CAP and RNA polymerase interactions with thelacpromoter: binding stoichiometry and long range effects

1983 • 150 citations

Sequence-specific positioning of core histones on an 860 base-pair DNA

1987 • 134 citations

Model of specific complex between catabolite gene activator protein and B-DNA suggested by electrostatic complementarity.

1984 • 132 citations

Bending and flexibility of kinetoplast DNA

1986 • 125 citations

A new approach to the study of sequence‐dependent properties of polynucleotides

1970 • 116 citations

Conformational changes in a replication origin induced by an initiator protein

1985 • 115 citations

The γδ resolvase induces an unusual DNA structure at the recombinational crossover point

1987 • 107 citations

Role of glutamic acid-181 in DNA-sequence recognition by the catabolite gene activator protein (CAP) of Escherichia coli: altered DNA-sequence-recognition properties of [Val181]CAP and [Leu181]CAP.

1987 • 89 citations

DNA Bending Induced by the Catabolite Activator Protein Allows Ring Formation of a 144 bp DNA

1987 • 88 citations

Electrostatic calculations and model‐building suggest that DNA bound to CAP is sharply bent

1987 • 77 citations

Variations of intramolecular ligation rates allow the detection of protein-induced bends in DNA.

1986 • 74 citations

Echinomycin and distamycin induce rotation of nucleosome core DNA

1986 • 65 citations

DNA wrapping and writhing

1987 • 59 citations

Unusual properties of promoter-up mutations in the Escherichia coli galactose operon and evidence suggesting RNA polymerase-induced DNA bending.

1987 • 57 citations

The change of DNA structure by specific binding of the cAMP receptor protein from rotation diffusion and dichroism measurements.

1984 • 53 citations

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