Bronchioloalveolar Adenocarcinoma of Lung

K-rasOncogene Activation as a Prognostic Marker in Adenocarcinoma of the Lung

1990 • 811 citations

Detection of p53 Gene Mutations in Human Brain Tumors by Single-strand Conformation Polymorphism Analysis of Polymerase Chain Reaction Products

1991 • 556 citations

Mutational Activation of the K-rasOncogene

1987 • 542 citations

Clonal Origin of Bladder Cancer

1992 • 538 citations

Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung.

1988 • 458 citations

Prognostic significance of p53 mutations and 3p deletions in primary, resected non-small cell lung cancer

1995 • 333 citations

A prognostic model of recurrence and death in stage I non-small cell lung cancer utilizing presentation, histopathology, and oncoprotein expression.

1995 • 300 citations

Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines

1992 • 298 citations

Rising incidence of bronchioloalveolar lung carcinoma and its unique clinicopathologic features

1994 • 268 citations

Mutations of the p53 Gene as a Predictor of Poor Prognosis in Patients With Non-Small-Cell Lung Cancer

1993 • 213 citations

Aberrations of the p53 tumor suppressor gene in human non-small cell carcinomas of the lung

1993 • 180 citations

Bronchioloalveolar carcinomas. Cell types, patterns of growth, and prognostic correlates

1986 • 163 citations

Genetic evidence for an independent origin of multiple preneoplastic and neoplastic lung lesions

1995 • 160 citations

Expression of p53 oncoprotein in non-small-cell lung cancer: a favorable prognostic factor.

1995 • 160 citations

Clonal Origin of Epithelial Ovarian Carcinoma: Analysis by Loss of Heterozygosity, p53 Mutation, and X-Chromosome Inactivation

1992 • 157 citations

Atypical Adenomatous Hyperplasia and Bronchoalveolar Lung Carcinoma

1996 • 133 citations

Fine structure of bronchiolo-alveolar cell carcinoma

1972 • 113 citations

Proliferative potential and p53 overexpression in precursor and early stage lesions of bronchioloalveolar lung carcinoma.

1995 • 96 citations

New Prognostic Factors in Lung Cancer

1995 • 95 citations

Ultrastructure of human bronchiolo-alveolar cell carcinoma

1975 • 89 citations

The multifocality of bronchioloalveolar lung carcinoma: evidence and implications of a multiclonal origin.

1994 • 84 citations

Comparative analysis of p53 gene mutations and protein accumulation in human non‐small‐cell lung cancer

1995 • 81 citations

Ovarian, peritoneal, and endometrial serous carcinoma: clonal origin of multifocal disease.

1996 • 81 citations

Prognostic significance of p53 andras p21 expression in nonsmall cell lung cancer

1995 • 81 citations

p53 and K-ras Mutational Genotyping in Pulmonary Carcinosarcoma, Spindle Cell Carcinoma, and Pulmonary Blastoma: Implications for Histogenesis

1997 • 80 citations

Detection of p53 in primary lung tumors and nonsmall cell lung carcinoma cell lines.

1991 • 78 citations

Detection of c-Ki-ras gene mutation in paraffin sections of adenocarcinoma and atypical bronchioloalveolar cell hyperplasia of human lung

1994 • 77 citations

Mutations of the p53 tumor suppressor gene as clonal marker for multiple primary lung cancers

1997 • 64 citations

K-ras-2 and p53 genotyping of intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses.

1996 • 60 citations

Distribution of p53 and K-ras mutations in human lung cancer tissues

1997 • 57 citations

Assessment of sensitivity and specificity of immunohistochemical staining of p53 in lung and head and neck cancers.

1995 • 56 citations

Alterations of K-ras, p53, and erbB-2/neu in human lung adenocarcinomas

1994 • 53 citations

Application of the p53 Gene Mutation Pattern for Differential Diagnosis of Primary Versus Metastatic Lung Carcinomas

1993 • 42 citations

Application of the p53 Gene Mutation Pattern for Differential Diagnosis of Primary Versus Metastatic Lung Carcinomas

1993 • 42 citations

Polymorphism of the pentanucleotide repeat d(AAAAT) within intron 1 of the human tumor suppressor gene p53 (17p13.1)

1995 • 26 citations

Molecular genetic tumor markers in the early diagnosis and screening of non-small-cell lung cancer

1995 • 23 citations

Simultaneous Use of the PCR-SSCP Method and Immunohistochemistry for Increasing the Detection Efficacy of p53 Abnormalities in Human Lung Cancer

1995 • 13 citations

Potential utility of p53 immunopositivity in differentiation of adenocarcinomas from reactive epithelial atypias of the lung

1996 • 9 citations

Immunohistochemical analysis of p53 mutations in bronchioloalveolar carcinoma and conventional pulmonary adenocarcinoma.

1995 • 9 citations