Tryptophan depletion in obsessive-compulsive patients

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Tryptophan depletion causes a rapid lowering of mood in normal males

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Mood-Lowering Effect of Tryptophan Depletion

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THE AMINO ACID REQUIREMENTS OF MAN

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Controlled Comparisons of Clomipramine and Fluoxetine in the Treatment of Obsessive-Compulsive Disorder

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Biochemical aspects of tryptophan depletion in primates

1989 • 190 citations

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Dose-response decrease in plasma tryptophan and in brain tryptophan and serotonin after tryptophan-free amino acid mixtures in rats

1989 • 161 citations

The serotonin hypothesis of obsessive compulsive disorder: implications of pharmacologic challenge studies.

1992 • 145 citations

Tryptophan Depletion in Patients With Obsessive-Compulsive Disorder Who Respond to Serotonin Reuptake Inhibitors

1994 • 133 citations

Acute tryptophan depletion blocks morphine analgesia in the cold-pressor test in humans

1992 • 104 citations

Decrease in plasma tryptophan after tryptophan-free amino acid mixtures in man

1988 • 89 citations

Cycloheximide blocks the fall of plasma and tissue tryptohan levels after tryptohan-free amino acid mixtures

1991 • 55 citations

Plasma tryptophan levels and plasma tryptophan/ neutral amino acids ratio in patients with mood disorder, patients with obsessive-compulsive disorder, and normal subjects

1992 • 39 citations

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Data Entry and Verification

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