Purification and Characterization of a Naturally Occurring Vascular Endothelial Growth Factor · Placenta Growth Factor Heterodimer

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

1989 • 4,988 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

Angiogenic Factors

1987 • 3,702 citations

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

1989 • 2,267 citations

Vascular Permeability Factor, an Endothelial Cell Mitogen Related to PDGF

1989 • 2,090 citations

The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing

1991 • 1,991 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor.

1993 • 1,391 citations

Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis.

1989 • 1,282 citations

Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR.

1994 • 1,104 citations

Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor.

1991 • 999 citations

The vascular endothelial growth factor family of polypeptides

1991 • 652 citations

Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.

1994 • 584 citations

Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculo stellate cells.

1989 • 568 citations

Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis.

1993 • 534 citations

Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor.

1990 • 368 citations

Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14.

1993 • 317 citations

A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain.

1988 • 317 citations

Hypoxia Is a Strong Inducer of Vascular Endothelial Growth Factor mRNA Expression in the Heart

1993 • 308 citations

Vascular endothelial growth factor: A new member of the platelet-derived growth factor gene family

1989 • 308 citations

Pure brain-derived acidic fibroblast growth factor is a potent angiogenic vascular endothelial cell mitogen with sequence homology to interleukin 1.

1985 • 294 citations

Human Vascular Permeability Factor

1989 • 282 citations

Fibroblast growth factors

1987 • 273 citations

Purification and characterization of acidic fibroblast growth factor from bovine brain.

1984 • 267 citations

Developmental expression of binding sites and messenger ribonucleic acid for vascular endothelial growth factor suggests a role for this protein in vasculogenesis and angiogenesis.

1993 • 262 citations

Purification and properties of porcine platelet-derived growth factor.

1984 • 260 citations

A Heparin-Binding Form of Placenta Growth Factor (PlGF-2) is Expressed in Human Umbilical Vein Endothelial Cells and in Placenta

1993 • 245 citations

Purification of a glycoprotein vascular endothelial cell mitogen from a rat glioma-derived cell line.

1990 • 230 citations

Conditioned Medium from Mouse Sarcoma 180 Cells Contains Vascular Endothelial Growth Factor

1990 • 101 citations

Specificity of Vascular Endothelial Cell Growth Factor Receptor Ligand Binding Domains

1994 • 83 citations

Mechanism of platelet-derived growth factor (PDGF) AA, AB, and BB binding to alpha and beta PDGF receptor.

1993 • 83 citations

An Endothelial Cell Growth Factor from the Mouse Neuroblastoma Cell Line NB41

1989 • 71 citations

Localization of Acidic Fibroblast Growth Factor within the Mouse Brain Using Biochemical and Immunocytochemical Techniques

1992 • 31 citations