Discovery of 4-{4-[3-(Pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}-N-(tetrahydro-2H- pyran-4-yl)benzamide (GW788388): A Potent, Selective, and Orally Active Transforming Growth Factor-β Type I Receptor Inhibitor

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1997 • 6,184 citations

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2000 • 2,405 citations

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2000 • 2,354 citations

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1998 • 1,763 citations

Transcriptional Activators of TGF-β Responses: Smads

1998 • 1,024 citations

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

1990 • 1,002 citations

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2000 • 907 citations

Neutralization of TGF-β by Anti-TGF-β Antibody Attenuates Kidney Hypertrophy and the Enhanced Extracellular Matrix Gene Expression in STZ-Induced Diabetic Mice

1996 • 658 citations

Crystal Structure of the Cytoplasmic Domain of the Type I TGF β Receptor in Complex with FKBP12

1999 • 433 citations

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2000 • 243 citations

Synthesis and Activity of New Aryl- and Heteroaryl-Substituted Pyrazole Inhibitors of the Transforming Growth Factor-β Type I Receptor Kinase Domain

2003 • 231 citations

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2004 • 198 citations

Voltage-dependent InsP3- insensitive calcium channels in membranes of pancreatic endoplasmic reticulum vesicles

1990 • 80 citations

Experimental and genetic rat models of chronic renal failure

1993 • 62 citations

Podocytic degeneration and regeneration in puromycin aminonucleoside nephropathy in the rat

1995 • 15 citations

Experimental Focal Segmental Glomerulosclerosis: Correlation with Protein Excretion, Glomerular Filtration Rate, and Renal Plasma Flow

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Multiple regions of chromosome 16Q demonstrating LOH in hepatocellular carcinomas

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