Accelerating on a Treadmill: ADF/Cofilin Promotes Rapid Actin Filament Turnover in the Dynamic Cytoskeleton

Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes.

1989 • 1,268 citations

Actin Depolymerizing Factor (ADF/Cofilin) Enhances the Rate of Filament Turnover: Implication in Actin-based Motility

1997 • 1,028 citations

Cellular motions and thermal fluctuations: the Brownian ratchet

1993 • 874 citations

Actin polymerization is induced by Arp 2/3 protein complex at the surface of Listeria monocytogenes

1997 • 598 citations

Thermodynamics of the polymerization of protein

1975 • 596 citations

The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization

1992 • 533 citations

Mutations in twinstar, a Drosophila gene encoding a cofilin/ADF homologue, result in defects in centrosome migration and cytokinesis.

1995 • 317 citations

Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts

1994 • 282 citations

Human actin depolymerizing factor mediates a pH-sensitive destruction of actin filaments

1993 • 279 citations

The ADF/Cofilin Proteins: Stimulus-responsive Modulators of Actin Dynamics

1995 • 255 citations

Cofilin is an essential component of the yeast cortical cytoskeleton.

1993 • 254 citations

Characterization of actin filament severing by actophorin from Acanthamoeba castellanii.

1991 • 247 citations

Xenopus Actin Depolymerizing Factor/Cofilin (XAC) Is Responsible for the Turnover of Actin Filaments in Listeria monocytogenes Tails

1997 • 219 citations

New horizons for cytokinesis

1995 • 196 citations

Xenopus laevis actin-depolymerizing factor/cofilin: a phosphorylation-regulated protein essential for development.

1996 • 187 citations

Elongation of actin filaments is a diffusion-limited reaction at the barbed end and is accelerated by inert macromolecules.

1986 • 167 citations

Host cell actin assembly is necessary and likely to provide the propulsive force for intracellular movement of Listeria monocytogenes

1992 • 164 citations

Overexpression of cofilin stimulates bundling of actin filaments, membrane ruffling, and cell movement in Dictyostelium.

1996 • 147 citations

Tertiary Structure of Destrin and Structural Similarity between Two Actin-Regulating Protein Families

1996 • 137 citations

Pollen specific expression of maize genes encoding actin depolymerizing factor-like proteins.

1996 • 135 citations

Recent quantitative studies of actin filament turnover during cell locomotion

1993 • 119 citations

Small actin-binding proteins: the β-thymosin family

1993 • 119 citations

Actophorin preferentially binds monomeric ADP‐Actin over ATP‐bound actin: consequences for cell locomotion

1994 • 117 citations

Focusing on unpolymerized actin.

1993 • 94 citations

Molecular cloning and characterization of anther-preferential cDNA encoding a putative actin-depolymerizing factor

1993 • 90 citations

The actin filament severing protein actophorin promotes the formation of rigid bundles of actin filaments crosslinked with alpha-actinin.

1991 • 88 citations

Concentration of cofilin, a small actin‐binding protein, at the cleavage furrow during cytokinesis

1995 • 71 citations

Actin.

1995 • 41 citations