Nimodipine enhances spontaneous activity of hippocampal pyramidal neurons in aging rabbits at a dose that facilitates associative learning

The Cholinergic Hypothesis of Geriatric Memory Dysfunction

1982 • 5,422 citations

Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats

1973 • 1,307 citations

The Neurobiology of Learning and Memory

1986 • 1,124 citations

Neurobiology of the hippocampus

1984 • 1,096 citations

Cerebellum: Essential Involvement in the Classically Conditioned Eyelid Response

1984 • 902 citations

Senile dementia of the Alzheimer type

1983 • 835 citations

Experimental methods and instrumentation in psychology

1966 • 789 citations

Control of the repetitive discharge of rat CA 1 pyramidal neurones in vitro.

1984 • 748 citations

Action potential repolarization and a fast after‐hyperpolarization in rat hippocampal pyramidal cells.

1987 • 694 citations

Hippocampectomy disrupts trace eye-blink conditioning in rabbits.

2015 • 673 citations

Hippocampus and trace conditioning of the rabbit's classically conditioned nictitating membrane response.

1986 • 671 citations

Hippocampectomy disrupts trace eye-blink conditioning in rabbits.

1990 • 581 citations

A calcium-activated hyperpolarization follows repetitive firing in hippocampal neurons

1980 • 576 citations

Calcium-dependent current generating the afterhyperpolarization of hippocampal neurons

1986 • 560 citations

Hippocampus and trace conditioning of the rabbit's classically conditioned nictitating membrane response.

1986 • 560 citations

Properties of two calcium‐activated hyperpolarizations in rat hippocampal neurones.

1987 • 554 citations

Prolonged Ca ²⁺ -Dependent Afterhyperpolarizations in Hippocampal Neurons of Aged Rats

1984 • 489 citations

Participation of calcium spikes during intrinsic burst firing in hippocampal neurons

1978 • 425 citations

Afterpotential generation in hippocampal pyramidal cells.

1981 • 401 citations

Electrophysiological characteristics of hippocampal complex-spike cells and theta cells

1981 • 392 citations

Local circuit interactions between oriens/alveus interneurons and CA1 pyramidal cells in hippocampal slices: electrophysiology and morphology

1987 • 391 citations

Single-unit analysis of different hippocampal cell types during classical conditioning of rabbit nictitating membrane response

1983 • 387 citations

Hippocampal granule cells are necessary for normal spatial learning but not for spatially-selective pyramidal cell discharge

1989 • 374 citations

Long-term stability of the place-field activity of single units recorded from the dorsal hippocampus of freely behaving rats

1990 • 364 citations

Place cells and silent cells in the hippocampus of freely-behaving rats

1989 • 333 citations

Physiological and morphological identification of a nonpyramidal hippocampal cell type

1978 • 332 citations

Initial localization of the memory trace for a basic form of learning.

1982 • 332 citations

An after‐hyperpolarization of medium duration in rat hippocampal pyramidal cells.

1989 • 322 citations

The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system

1987 • 318 citations

Conditioning-specific membrane changes of rabbit hippocampal neurons measured in vitro.

1986 • 318 citations

Nimodipine Facilitates Associative Learning in Aging Rabbits

1989 • 305 citations

Stratum lacunosum-moleculare interneurons of hippocampal CA1 region. I. Intracellular response characteristics, synaptic responses, and morphology

1988 • 274 citations

Lesions of the hippocampal formation but not lesions of the fornix or the mammillary nuclei produce long-lasting memory impairment in monkeys

1989 • 266 citations

Does the capacity of working memory change with age?

1988 • 252 citations

Pharmacological basis for the use of nimodipine in central nervous system disorders

1989 • 248 citations

Hippocampal pyramidal cells: significance of dendritic ionic conductances for neuronal function and epileptogenesis

1979 • 244 citations

Aminergic systems in Alzheimer's disease and Parkinson's disease

1987 • 241 citations

Loss of perforated synapses in the dentate gyrus: morphological substrate of memory deficit in aged rats.

1986 • 231 citations

New Drugs Annual—Cardiovascular Drugs

1984 • 222 citations

Aging and the physiology of spatial memory

1988 • 217 citations

Classical conditioning reduces amplitude and duration of calcium-dependent afterhyperpolarization in rabbit hippocampal pyramidal cells

1989 • 204 citations

A driveable bundle of microwires for collecting single-unit data from freely-moving rats

1984 • 198 citations

‘Increased calcium-current’ hypothesis of brain aging

1987 • 192 citations

Involvement of free radicals in dementia of the Alzheimer type: A hypothesis

1990 • 191 citations

Characteristics of a slow hyperpolarizing synaptic potential in rat hippocampal pyramidal cells in vitro

1984 • 182 citations

Senile Dementia of the Alzheimer Type

1985 • 178 citations

Parkinsonian Symptomatology An Anatomical and Physiological Analysisaa

1988 • 168 citations

Rat hippocampal neurons in culture: potassium conductances

1984 • 165 citations

Cellular Mechanisms of Conditioning and Behavioral Plasticity

1988 • 132 citations

The Calcium Channel: Structure, Function and Implications

1988 • 130 citations

Diagnosis and Treatment of Senile Dementia

1989 • 114 citations

Evidence for two types of afterhyperpolarization in CA1 pyramidal cells in the hippocampus

1981 • 110 citations

Pharmacology of Nimodipine

1988 • 106 citations

AHP reductions in rabbit hippocampal neurons during conditioning correlate with acquisition of the learned response

1988 • 100 citations

Age-related disruption of trace but not delay classical conditioning of the rabbit's nictitating membrane response.

1985 • 99 citations

Hippocampal pyramidal cells and aging in the human: A quantitative study of neuronal loss in sectors CA1 to CA4

1986 • 99 citations

Increased electrotonic coupling in aged rat hippocampus: A possible mechanism for cellular excitability changes

1987 • 98 citations

Quantitative autoradiographic mapping in rat brain of the receptor of apamin, a polypeptide toxin specific for one class of Ca2+-dependent K+ channels

1986 • 87 citations

Age-related disruption of trace but not delay classical conditioning of the rabbit's nictitating membrane response.

1985 • 80 citations

Aging and cognition: Facilitation of recent memory in aged nonhuman primates by nimodipine

1990 • 77 citations

Chronically elevating plasma Mg2+ improves hippocampal frequency potentiation and reversal learning in aged and young rats

1984 • 75 citations

Learning-induced afterhyperpolarization reductions in hippocampus are specific for cell type and potassium conductance

1990 • 74 citations

Medial septal modulation of hippocampal theta cell discharges

1986 • 73 citations

Age differences in the acquisition and extinction of the conditioned eyelid response.

1959 • 71 citations

Impaired up-regulation of type II corticosteroid receptors in hippocampus of aged rats

1989 • 61 citations

Age-related disruption of classical conditioning: A model systems approach to memory disorders

1988 • 57 citations

Is senile dementia of the Alzheimer type associated with hippocampal plasticity?

1988 • 56 citations

Dietary nimodipine improves associative learning in aging rabbits

1990 • 55 citations

Biogenic amines and their metabolites in Alzheimer's disease: noradrenaline, 5-hydroxytryptamine and 5-hydroxyindole-3-acetic acid depleted in hippocampus but not in substantia innominata

1989 • 54 citations

Chapter 20 Cell-specific pathology in neural systems of the temporal lobe in Alzheimer's disease

1986 • 53 citations

Cognitive and brain imaging measures of Alzheimer's disease

1988 • 48 citations

Effects of nimodipine on cerebral vasoconstrictor responses

1984 • 43 citations

Septo-hippocampal neurons in the aged rat: Relation between their electrophysiological and pharmacological properties and behavioral performances

1989 • 40 citations

Cognitive Function in Normal Aging and Early Dementia

1985 • 38 citations

Shape of frequency-current curves in CAI pyramidal cells in the hippocampus

1981 • 31 citations

Septo-hippocampal neurons: altered properties in the aged rat

1987 • 30 citations

Nimodipine ameliorates aging-related changes in open-field behaviors of the rabbit

1989 • 29 citations

Old Rats as an Animal Model for Senile Dementia: Behavioural Effects of Nimodipine

1989 • 27 citations

Aging of the Brain and Alzheimer's Disease

1986 • 27 citations

Regional distribution of calcium channel ligand (1,4-dihydropyridine) binding sites and 45Ca2+ uptake processes in rat brain

1987 • 25 citations

Age-related alterations in noradrenergic input to the hippocampal formation: structural and functional studies in intraocular transplants

1989 • 25 citations

Transfer of Nimodipine and Another Calcium Antagonist Across the Blood-Brain Barrier and Their Regional Distribution In Vivo

1989 • 19 citations

Cognitive Enhancing Agents: Current Status in the Treatment of Alzheimer's Disease

1988 • 17 citations

Local cerebral glucose utilization and local cerebral blood flow in conscious rats after administration of flunarizine

1987 • 17 citations

A model systems approach to age-related memory disorders.

1988 • 17 citations

Conditioning-Specific Biophysical Alterations in Rabbit Hippocampus

1988 • 15 citations

Increased Calcium Currents in Rat Hippocampal Neurons During Aging

1988 • 10 citations

Classical Conditioning of the Nictitating Membrane Response in Aged Rabbits

1985 • 9 citations

Vasoconstrictor effect of the Ca2+ agonist Bay K 8644 on human cerebral arteries

1989 • 8 citations

Strategies for Treating Alzheimer’s Disease and Age-Associated Memory Impairment

1989 • 3 citations