Impaired cytosolic free calcium response in splenic T-cells from mice fed with ethanol-containing diet

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

T cell growth factor receptors. Quantitation, specificity, and biological relevance

1981 • 1,087 citations

T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

1982 • 1,026 citations

The Interleukin-2 T-Cell System: A New Cell Growth Model

1984 • 935 citations

Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen.

1984 • 742 citations

The Role of the T3/Antigen Receptor Complex in T-Cell Activation

1986 • 627 citations

N‐Methyl‐D‐Aspartate Receptors and Ethanol: Inhibition of Calcium Flux and Cyclic GMP Production

1989 • 566 citations

Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway.

1984 • 506 citations

Free cytoplasmic calcium concentration and the mitogenic stimulation of lymphocytes.

1983 • 466 citations

Interleukin-2 stimulates association of protein kinase C with plasma membrane

1985 • 384 citations

Ethanol and the Nervous System

1989 • 362 citations

The role of calcium ions in initiating transformation of lymphocytes

1974 • 271 citations

Mitogenic Properties of a Calcium Ionophore, A23187

1974 • 203 citations

Increase in cytosolic free calcium concentration is an intracellular messenger for the production of interleukin 2 but not for expression of the interleukin 2 receptor.

1985 • 164 citations

Role of T cells and adherent cells in age-related decline in murine interleukin 2 production.

1982 • 153 citations

Relationship of cAMP and calcium messenger systems in prostaglandin-stimulated UMR-106 cells.

1988 • 150 citations

Role of membrane potential in the regulation of lectin‐induced calcium uptake

1984 • 121 citations

Inhibition of PHA-stimulated lymphocyte transformation by plasma from patients with advanced alcoholic cirrhosis.

1971 • 120 citations

Interleukin 2-induced lymphocyte proliferation is independent of increases in cytosolic-free calcium concentrations.

1985 • 113 citations

Application of Transformations to Normalize the Distribution of Plaque-Forming Cells

1974 • 103 citations

Calcium and lymphocyte activation

1976 • 100 citations

Antigen-dependent increase in cytosolic free calcium in specific human T-lymphocyte clones

1985 • 92 citations

Mechanisms of Suppression of Cellular Immunity Induced by Ethanol

1989 • 88 citations

Characterization of the role for calcium influx in mitogen‐induced triggering of human T cells. Identification of calcium‐dependent and calcium‐independent signals

1986 • 86 citations

Cultured lymphocytes from alcoholic subjects have altered cAMP signal transduction.

1988 • 84 citations

Functional analysis of T-cell subsets in chronic experimental alcoholism.

1987 • 83 citations

Transmembrane signals in the activation of T lymphocytes by mitogenic antigens

1988 • 83 citations

Alcohols stimulate γ-aminobutyric acid receptor-mediated chloride uptake in brain vesicles: correlation with intoxication potency

1988 • 80 citations

A novel mechanism of immunosuppression mediated by ethanol

1986 • 78 citations

Effects of ethyl alcohol on human peripheral lymphocytes.

1985 • 75 citations

Uptake of extracellular Ca²⁺ and not recruitment from internal stores is essential for T lymphocyte proliferation

1988 • 72 citations

Impaired Lymphocyte Proliferative Response to Mitogen in Alcoholic Patients. Absence of a Relation to Liver Disease Activity

1988 • 69 citations

Signals involved in T cell activation. II. Distinct roles of intact accessory cells, phorbol esters, and interleukin 1 in activation and cell cycle progression of resting T lymphocytes.

1986 • 67 citations

Immune Responses in Alcoholic Liver Disease

1986 • 53 citations

Cyclic nucleotides in mitogen-induced lymphocyte proliferation

1982 • 53 citations

Association of Tuberculosis With Alcoholism

1976 • 40 citations

ROLE OF CYCLIC NUCLEOTIDES IN REGULATING LYMPHOCYTES

1979 • 38 citations

Alterations in Interleukin‐2 Utilization by T‐Cells from Rats Treated with an Ethanol‐Containing Diet

1990 • 37 citations

Alcohol and immune regulation I. in vivo effects of ethanol on concanavalin a sensitive thymic lymphocyte function

1988 • 34 citations

CYCLIC NUCLEOTIDES AND CALCIUM IN LYMPHOCYTE REGULATION AND ACTIVATION*

1979 • 34 citations

Immunotoxicity of Alcohol in Young and Old Mice. I. In vitro Suppressive Effects of Ethanol on the Activities of T and B Immune Cells of Aging Mice

1990 • 31 citations

Direct mitogenic effect of ionophore A23187 on isolated human T helper lymphocytes

1984 • 30 citations

Ligands, receptors and signal transduction in regulation of lymphocyte function

1991 • 27 citations

Mechanism of ethanol-mediated immunosuppression in mice: Ethanol suppresses T-cell proliferation without affecting IL2 production and IL2 receptor expression

1992 • 20 citations

Immunotoxicity of alcohol in young and old mice. II. Impaired T cell proliferation and T cell-dependent antibody responses of young and old mice fed ethanol-containing liquid diet

1991 • 18 citations

The Effect of Alcohol Ingestion on the Susceptibility of Mice to Viral Infections

1982 • 16 citations

Bacterial endocarditis and cirrhosis of the liver

1968 • 15 citations

The Role of Calcium in Stimulation of Activated T Lymphocytes with Interleukin 2

1986 • 10 citations

Ethanol inhibits mitogen-induced calcium mobilization in mouse splenocytes

1992 • 8 citations

Can increased beta-endorphins explain the etiology of premenstrual syndrome?

1982 • 7 citations

The immune response in alcoholics without liver disease: a review.

1982 • 6 citations

The immune response in alcoholics without liver disease: A review

1982 • 5 citations