Ethanol and the Nervous System

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Neurogenetic Adaptive Mechanisms in Alcoholism

1987 • 2,300 citations

Ethanol Inhibits NMDA-Activated Ion Current in Hippocampal Neurons

1989 • 1,456 citations

Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's disease

1983 • 811 citations

Osmotic Demyelination Syndrome Following Correction of Hyponatremia

1986 • 757 citations

Central pontine myelinolysis: a hitherto undescribed disease occurring in alcoholic and malnourished patients.

1959 • 735 citations

Event-Related Brain Potentials in Boys at Risk for Alcoholism

1984 • 717 citations

The Effects of Alcoholism on Skeletal and Cardiac Muscle

1989 • 669 citations

Teratogenic Effects of Alcohol in Humans and Laboratory Animals

1980 • 664 citations

Clinical signs in the Wernicke-Korsakoff complex: a retrospective analysis of 131 cases diagnosed at necropsy.

1986 • 631 citations

Treatment of Symptomatic Hyponatremia and Its Relation to Brain Damage

1987 • 601 citations

Central Pontine Myelinolysis

1959 • 576 citations

Hyponatremia, Convulsions, Respiratory Arrest, and Permanent Brain Damage after Elective Surgery in Healthy Women

1986 • 573 citations

N‐Methyl‐D‐Aspartate Receptors and Ethanol: Inhibition of Calcium Flux and Cyclic GMP Production

1989 • 566 citations

A Selective Imidazobenzodiazepine Antagonist of Ethanol in the Rat

1986 • 545 citations

Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes.

1986 • 543 citations

Brain Lesions in Alcoholics

1993 • 530 citations

An Experimental Study of the Etiology of “Rum Fits” and Delirium Tremens

1955 • 518 citations

Presence of Nonoxidative Ethanol Metabolism in Human Organs Commonly Damaged by Ethanol Abuse

1986 • 487 citations

Severe Symptomatic Hyponatremia: Treatment and Outcome

1987 • 485 citations

Incidence of fetal alcohol syndrome and economic impact of FAS-related anomalies

1987 • 477 citations

Status epilepticus

1980 • 468 citations

Biochemical and Molecular Basis of Alcohol-Induced Injury to Liver and Other Tissues

1988 • 452 citations

Wernicke's Encephalopathy

1985 • 428 citations

Reversible Cerebral Atrophy in Recently Abstinent Chronic Alcoholics Measured by Computed Tomography Scans

1978 • 405 citations

PONTINE AND EXTRAPONTINE MYELINOLYSIS

1979 • 398 citations

Abnormality of a Thiamine-Requiring Enzyme in Patients with Wernicke-Korsakoff Syndrome

1977 • 397 citations

The Wernicke-Korsakoff Syndrome and Related Neurologic Disorders Due to Alcoholism and Malnutrition

1990 • 393 citations

The incidence of Wernicke's encephalopathy in Australia--a neuropathological study of 131 cases.

1983 • 343 citations

A Restricted Form of Cerebellar Cortical Degeneration Occurring in Alcoholic Patients

1959 • 328 citations

Ethanol Specifically Potentiates GABA-Mediated Neurotransmission in Feline Cerebral Cortex

1980 • 322 citations

Rapid Correction of Hyponatremia Causes Demyelination: Relation to Central Pontine Myelinolysis

1981 • 320 citations

Association between rise in serum sodium and central pontine myelinolysis

1982 • 302 citations

Gamma-aminobutyric acid and alcohol actions: Neurochemical studies of long sleep and short sleep mice

1986 • 280 citations

Ethanol potentiation of GABAergic transmission in cultured spinal cord neurons involves gamma-aminobutyric acidA-gated chloride channels.

1988 • 278 citations

The Role of Abstinence in the Genesis of Alcoholic Epilepsy

1967 • 275 citations

Blood ethanol levels in sober alcohol users seen in an emergency room

1981 • 262 citations

Differences in Platelet Enzyme Activity between Alcoholics and Nonalcoholics

1988 • 253 citations

Central pontine myelinolysis following rapid correction of hyponatremia

1983 • 244 citations

Are we drinking our neurones away?

1987 • 233 citations

Cholinergic-rich brain transplants reverse alcohol-induced memory deficits

1988 • 221 citations

Chronic ethanol causes heterologous desensitization of receptors by reducing αsmessenger RNA

1988 • 220 citations

Calcium channel antagonists decrease the ethanol withdrawal syndrome

1986 • 217 citations

CEREBRAL DISORDER IN ALCOHOLISM SYNDROMES OF IMPAIRMENT

1981 • 216 citations

Intrauterine alcohol and nicotine exposure: Attention and reaction time in 4-year-old children.

1984 • 214 citations

Brain shrinkage in chronic alcoholics: a pathological study.

1985 • 213 citations

Central pontine and extrapontine myelinolysis: a report of 58 cases.

1987 • 212 citations

Alcoholic Myopathy in Heart and Skeletal Muscle

1979 • 208 citations

Central pontine myelinolysis and its imitators: MR findings.

1988 • 205 citations

Inhibition of synaptosomal calcium uptake by ethanol.

1980 • 203 citations

Increased dihydropyridine-sensitive calcium channels in rat brain may underlie ethanol physical dependence

1987 • 203 citations

Central pontine myelinolysis Considerations on etiology, diagnosis, and treatment

1979 • 202 citations

Ethanol regulates calcium channels in clonal neural cells.

1986 • 197 citations

Alcoholic neuropathy: Clinical, electrophysiological, and biopsy findings

1977 • 195 citations

Ethanol Produces Muscle Damage in Human Volunteers

1972 • 195 citations

IQ at age 4 in relation to maternal alcohol use and smoking during pregnancy.

1989 • 191 citations

Ethanol regulation of adenosine receptor-stimulated cAMP levels in a clonal neural cell line: an in vitro model of cellular tolerance to ethanol.

1986 • 190 citations

Alcohol Consumption and Withdrawal in New-Onset Seizures

1988 • 188 citations

Brain atrophy in chronic alcoholic patients: a quantitative pathological study.

1985 • 185 citations

Alcohol teratogenicity in the human: A detailed assessment of specificity, critical period, and threshold

1987 • 185 citations

Brain Atrophy and Intellectual Impairment in Heavy Drinkers—A Clinical, Psychometric and Computerized Tomography Study

1978 • 185 citations

Chronic ethanol administration alters gamma-aminobutyric acid, pentobarbital and ethanol-mediated 36Cl- uptake in cerebral cortical synaptoneurosomes.

1988 • 184 citations

Alcohol Withdrawal and Noradrenergic Function

1987 • 182 citations

Changing concep in treatment of severe symptomatic hyponatremia. Rapid correction and possible relation to central pontine myelinolysis

1985 • 175 citations

Loss of neurons in the rat basal forebrain cholinergic projection system after prolonged intake of ethanol

1988 • 173 citations

Rapid correction of severe hyponatremia with intravenous hypertonic saline solution

1982 • 170 citations

Basal and adenosine receptor-stimulated levels of cAMP are reduced in lymphocytes from alcoholic patients.

1987 • 170 citations

Ethanol enhances GABA-induced 36Cl-influx in primary spinal cord cultured neurons

1986 • 168 citations

CEREBRAL BERIBERI (WERNICKE'S ENCEPHALOPATHY)

1947 • 164 citations

Morphological alterations in rat CA1 hippocampal pyramidal cell dendrites resulting from chronic ethanol consumption and withdrawal

1984 • 163 citations

Alcoholic Skeletal Myopathy, A Clinical and Pathological Study

1985 • 159 citations

Inhibition of fast- and slow-phase depolarization-dependent synaptosomal calcium uptake by ethanol.

1983 • 158 citations

Maternal Alcohol Use and Neonatal Habituation Assessed with the Brazelton Scale

1983 • 155 citations

Central pontine myelinolysis in severely burned patients

1988 • 153 citations

Randomized Clinical Trial of Atenolol in Patients with Alcohol Withdrawal

1985 • 152 citations

The Relationship between Cognitive Dysfunction and Brain Damage in Alcoholics: Causal, Interactive, or Epiphenomenal?

1981 • 147 citations

Korsakoff's syndrome: radiological (CT) findings and neuropsychological correlates

1988 • 146 citations

Biologic Concomitants of Alcoholism

1970 • 143 citations

Molecular interactions of ethanol with GABAergic system and potential of RO15–4513 as an ethanol antagonist

1988 • 138 citations

A Golgi study of mouse hippocampal CA1 pyramidal neurons following perinatal ethanol exposure

1981 • 137 citations

Central Pontine Myelinolysis<subtitle>TWO CASES WITH ASSOCIATED ELECTROLYTE DISTURBANCE</subtitle>

1976 • 136 citations

Pharmacology of Alcohol

1983 • 131 citations

ALCOHOL-INDUCED BRAIN DAMAGE AND LIVER DAMAGE IN YOUNG MALES

1979 • 131 citations

Mamillary body atrophy in Wernicke's encephalopathy: Antemortem identification using magnetic resonance imaging

1987 • 130 citations

Hyponatremia and central pontine myeIinolysis

1977 • 126 citations

Mortality in alcoholics with autonomic neuropathy.

1988 • 124 citations

Clinical Assessment of Cognition in Alcoholism

1986 • 123 citations

Diazepam and Paraldehyde for Treatment of Severe Delirium Tremens

1975 • 121 citations

Ethanol differentially regulates G proteins in neural cells

1988 • 119 citations

Reversible brain shrinkage in abstinent alcoholics, measured by MRI

1988 • 116 citations

ALCOHOLIC DEMENTIA: A HYPOTHESIS

1986 • 116 citations

PONTINE AND EXTRAPONTINE MYELINOLYSIS FOLLOWING RAPID CORRECTION OF HYPONATRAEMIA

1988 • 115 citations

Sequence of metabolic, clinical, and histological events in experimental thiamine deficiency

1983 • 114 citations

Ethanol withdrawal in mice bred to be genetically prone or resistant to ethanol withdrawal seizures.

1986 • 110 citations

ENCEPHALOPATHY AND MYELINOLYSIS AFTER RAPID CORRECTION OF HYPONATRAEMIA

1987 • 106 citations

Activation of adenylate cyclase by alcohols requires the nucleotide-binding protein.

1984 • 106 citations

Serum prolactin levels in sons of alcoholics and control subjects

1987 • 105 citations

Alterations and recovery of dendritic spine density in rat hippocampus following long-term ethanol ingestion

1988 • 103 citations

Ethanol Modulation of Opiate Receptors in Cultured Neural Cells

1983 • 101 citations

THE CLINICAL SPECTRUM OF ALCOHOLIC PELLAGRA ENCEPHALOPATHY: A RETROSPECTIVE ANALYSIS OF 22 CASES STUDIED PATHOLOGICALLY

1988 • 100 citations

The induction and reversibility of cerebral acidosis in thiamine deficiency

1984 • 99 citations

Improvement of ataxia in alcoholic cerebellar atrophy through alcohol abstinence

1984 • 96 citations

Chronicity of hyponatremia as a factor in experimental myelinolysis

1984 • 93 citations

Skeletal Muscle Disease in Alcoholism

1984 • 92 citations

Central pontine myelinolysis

1984 • 92 citations

The benzodiazepine receptor inverse agonists FG 7142 and RO 15-4513 both reverse some of the behavioral effects of ethanol in a holeboard test

1987 • 90 citations

Effects of Chronic Ethanol Treatment on the β‐Adrenergic Receptor‐Coupled Adenylate Cyclase System of Mouse Cerebral Cortex

1987 • 90 citations

Intracranial lesions shown by CT scans in 259 cases of first alcohol‐related seizures

1988 • 89 citations

Prevention of the Wernicke-Korsakoff Syndrome

1978 • 88 citations

Effects of Ro15-4513 and other benzodiazepine receptor inverse agonists on alcohol-induced intoxication in the rat.

1988 • 87 citations

Cultured lymphocytes from alcoholic subjects have altered cAMP signal transduction.

1988 • 84 citations

COMA IN THE WERNICKE-KORSAKOFF SYNDROME

1978 • 84 citations

Transketolase abnormality in cultured fibroblasts from familial chronic alcoholic men and their male offspring.

1987 • 84 citations

Follow-Up Studies of Children with Fetal Alcohol Syndrome

1987 • 80 citations

Decreased Neuronal Inhibition in Vitro After Long-Tterm Administration of Ethanol

1984 • 79 citations

Calcium-Channel-Blocking Agent in the Treatment of Acute Alcohol Withdrawal – Caroverine versus Meprobamate in a Randomized Double-Blind Study

1987 • 78 citations

Ethanol and the γ‐Aminobutyric Acid‐Benzodiazepine Receptor Complex

1984 • 75 citations

Acute and chronic effects of ethanol on receptor-mediated phosphatidylinositol 4,5-bisphosphate breakdown in mouse brain.

1986 • 75 citations

Partially Reversible Cerebral Atrophy and Functional Improvement in Recently Abstinent Alcoholics

1984 • 73 citations

Muscarinic Cholinergic Receptor Subtypes in Hippocampus in Human Cognitive Disorders

1988 • 71 citations

Intermittent thiamine deficiency in the rhesus monkey. I. Progression of neurological signs and neuroanatomical lesions

1983 • 67 citations

Ethanol-induced component of 45Ca2+ uptake in PC12 cells is sensitive to Ca2+ channel modulating drugs

1987 • 67 citations

Ethanol increases the expression of functional delta-opioid receptors in neuroblastoma x glioma NG108-15 hybrid cells.

1986 • 65 citations

Synthesis of phosphatidylethanol--a potential marker for adult males at risk for alcoholism.

1988 • 65 citations

Prevalence of Low Monoamine Oxidase Function in Alcoholism

1987 • 64 citations

Effects of ethanol on stimulated inositol phospholipid hydrolysis in rat brain.

1986 • 63 citations

Effects of ethanol on 45Ca2+ uptake in synaptosomes and in PC12 cells

1987 • 58 citations

TWO TYPES OF BRAIN LESIONS IN WERNICKE'S ENCEPHALOPATHY

1985 • 57 citations

Vestibular paresis: a clinical feature of Wernicke's disease.

1969 • 55 citations

Chronic Alcohol Consumption Reduces the Cortical Layer Volumes and the Number of Neurons of the Rat Cerebellar Cortex

1987 • 55 citations

Brain shrinkage in alcoholics is not caused by changes in hydration: a pathological study.

1988 • 55 citations

Delirium tremens

1987 • 55 citations

Does a "moderate" alcohol intake damage the brain?

1988 • 53 citations

Prognosis of alcoholic peripheral neuropathy.

1984 • 52 citations

Interactions of the imidazodiazepine Ro 15–4513 with chemical convulsants

1988 • 51 citations

Epilepsy and Alcohol: The Influence of Social Alcohol Intake on Seizures and Treatment in Epilepsy

1983 • 50 citations

Decreased axonal transport in rat nerve following acute and chronic ethanol exposure

1987 • 49 citations

Computed Tomographic Findings in Wernicke-Korsakoff Syndrome

1984 • 49 citations

Alcohol and the Fetus: A Clinical Perspective

1984 • 48 citations

ETHANOL, THIAMINE AND BRAIN DAMAGE

1983 • 48 citations

PERIPHERAL NEUROPATHY AND MYOPATHY IN CHRONIC ALCOHOLISM

1986 • 48 citations

Computed Tomography Brain Scanning in Alcohol Withdrawal Seizures

1981 • 48 citations

Double-blind comparison of lorazepam and chlordiazepoxide in the treatment of the acute alcohol abstinence syndrome.

1983 • 47 citations

Alcoholic Rhabdomyolysis: An Experimental Model in the Rat

1980 • 46 citations

P300 and the Risk for Alcoholism: Family History, Task Difficulty, and Gender

1988 • 46 citations

Phosphatidylinositol from ethanol-fed rats confers membrane tolerance to ethanol.

1986 • 45 citations

The clinical versus radiological diagnosis of alcoholic cerebellar degeneration

1986 • 45 citations

Brain amino acids decrease in chronic hyponatremia and rapid correction causes brain dehydration: Possible clinical significance

1987 • 45 citations

Computed tomography in the diagnosis of Wernicke's encephalopathy: A radiological‐neuropathological correlation

1984 • 40 citations

Alcoholic Cerebellar Degeneration Is Not a Dose‐Dependent Phenomenon

1987 • 39 citations

Effects of chronic exposure to ethanol on the prostaglandin E1 receptor-mediated response and binding in a murine neuroblastoma clone (N1E-115).

1986 • 38 citations

Electrophysiologic effects of acute ethanol exposure. II. Alterations in the calcium component of action potentials from sensory neurons in dissociated culture

1982 • 38 citations

Antagonism of ethanol and pentobarbital actions by benzodiazepine inverse agonists: neurochemical studies.

1988 • 38 citations

Parameters affecting the course and results of delirium tremens treatment

1986 • 37 citations

Central nervous system catecholamine metabolism in Korsakoff's psychosis

1984 • 37 citations

Drinking habits and peripheral alcoholic neuropathy

1982 • 34 citations

Protective Effect of Steroids in Electrolyte-induced Demyelination

1987 • 34 citations

Comparative Effects of Chronic Exposure to Ethanol and Calcium Channel Antagonists on Calcium Channel Antagonist Receptors in Cultured Neural (PC12) Cells

1989 • 30 citations

Alcohol Withdrawal Seizures

1987 • 30 citations

Marchiafava-Bignami Syndrome

1989 • 28 citations

The activation of red blood cell transketolase in groups of patients especially at risk from thiamin deficiency

1987 • 28 citations

Possible role of thiamine in the nervous system

1982 • 26 citations

Variables Associated with Alcoholic Blackouts in Men

1985 • 26 citations

Genetics and the risk for alcoholism

1985 • 25 citations

Decreased 6‐hydroxymelatonin excretion in Korsakoff's psychosis

1984 • 24 citations

Zimelidine effects on memory impairments produced by ethanol

1983 • 24 citations

Association between Low Plasma Tryptophan and Blackouts in Male Alcoholic Patients

1985 • 22 citations

Accidents, Alcohol and Single-Cause Explanations; Lessons from the Grand Rapids Study

1968 • 21 citations

Effects of Ethanol on Nerve Impulse Activity

1979 • 20 citations

Calcium channel antagonist receptors in cerebral cortex from alcoholic patients

1989 • 20 citations

Effect of intravenously-administered putative and potential antagonists of ethanol on sleep time in ethanol-narcotized mice

1988 • 19 citations

Clonidine vs chlordiazepoxide in the management of acute alcohol withdrawal syndrome

1987 • 18 citations

Cerebellar degeneration in the rat following rapid correction of hyponatremia

1981 • 16 citations

Serum and muscle potassium in experimental alcoholic myopathy

1984 • 15 citations

Central Pontine Myelinolysis: A Complication of Hyponatremia or of Therapeutic Intervention?

1987 • 14 citations

Increased sensitivity of transmitter release to calcium in ethanol tolerance

1986 • 11 citations