844 — Charge transfer mechanism for carcinogenesis by alkylating and other agents

Aging: A Theory Based on Free Radical and Radiation Chemistry

1956 • 8,252 citations

Dietary Carcinogens and Anticarcinogens

1983 • 3,028 citations

Prooxidant States and Tumor Promotion

1985 • 2,541 citations

Superoxide Radical: An Endogenous Toxicant

1983 • 1,176 citations

Some current perspectives on chemical carcinogenesis in humans and experimental animals: Presidential Address.

1978 • 938 citations

DNA Modification and Cancer

1981 • 688 citations

The Chemical Effects ofNucleic Acid Alkylation and Their Relation to Mutagenesis and Carcinogen esis

1975 • 446 citations

Phagocytes as Carcinogens: Malignant Transformation Produced by Human Neutrophils

1985 • 443 citations

Ascorbic acid and cancer: a review.

1979 • 425 citations

The Prophylactic Portacaval Shunt

1972 • 373 citations

Spontaneous cancer and its possible relationship to oxygen metabolism.

1980 • 298 citations

N-nitroso alkylating agents: formation and persistence of alkyl derivatives in mammalian nucleic acids as contributing factors in carcinogenesis.

1979 • 276 citations

Stimulated Human Phagocytes Produce Cytogenetic Changes in Cultured Mammalian Cells

1983 • 262 citations

Iminium salts in organic chemistry

1976 • 236 citations

Role of Free Radicals in Mutation, Cancer, Aging, and the Maintenance of Life

1962 • 204 citations

The metabolic activation and nucleic acid adducts of naturally-occurring carcinogens: Recent results with ethyl carbamate and the spice flavors safrole and estragole

1983 • 166 citations

Electrochemical Reduction of Pyrimidine, Cytosine and Related Compounds: Polarography and Macroscale Electrolysis

1962 • 154 citations

Nuclear catalyzed antibiotic free radical formation.

1982 • 149 citations

A National Institutes of Health Workshop report. Free radicals in promotion--a chemical pathology study section workshop.

1983 • 117 citations

The mechanism of action of quinone antibiotics

1983 • 116 citations

Chemistry of Guanine and Its Biologically Significant Derivatives

1968 • 112 citations

Electrochemical Reduction of Purine, Adenine and Related Compounds: Polarography and Macroscale Electrolysis

1962 • 105 citations

Synthesis of Potential Anticancer Agents. XXV. Preparation of 6-Alkoxy-2-aminopurines²

1960 • 99 citations

Adducts from in vivo action of the carcinogen 4-hydroxyaminoquinoline 1-oxide in rats and from in vitro reaction of 4-acetoxyaminoquinoline 1-oxide with DNA and polynucleotides.

1985 • 69 citations

Two-stage carcinogenesis studies with asbestos in Fischer 344 rats.

1980 • 68 citations

Newer approaches to the study of the mechanisms of action of antitumor antibiotics

1982 • 61 citations

Interaction with Nucleic Acids of Carcinogenic and Mutagenic N-Nitroso Compounds

1976 • 58 citations

Species specificity of long-range electron transfer within the complex between zinc-substituted cytochrome c peroxidase and cytochrome c

1985 • 57 citations

Long range photoinduced electron transfer in a rigid polymer

1985 • 45 citations

Lipid peroxidation in microsomes induced by crocidolite fibres

1983 • 42 citations

Electrochemical Reduction of 6-Substituted Purines Correlation with Structural and Energetic Characteristics

1969 • 42 citations

Morbidity and mortality reduction by supplemental vitamin A or beta-carotene in CBA mice given total-body gamma-radiation.

1984 • 38 citations

Dose response for DNA alkylation, [3H]thymidine uptake into DNA, and O6-methylguanine-DNA methyltransferase activity in hepatocytes of rats and mice continuously exposed to dimethylnitrosamine.

1984 • 35 citations

The generation of potentially toxic, reactive iminium ions from the oxidative metabolism of xenobiotic N-alkyl compounds

1985 • 35 citations

Charge Transfer in the Mechanism of Drug Action Involving Quinoxaline Di-N-oxides

1985 • 31 citations

620. The polarographic reduction of some natural and artificial hydrogen-carriers in bacterial enzyme systems

1952 • 27 citations

MUTATION, CANCER, AND AGEING

1961 • 24 citations

Biochemistry of Cancer

1951 • 19 citations

The chemistry of 1,5-diblocked flavin. 1. Interconversion of the reduced, radical, and oxidized forms of 1,10-ethano-5-ethyllumiflavin

1983 • 17 citations

Syntheses of agelasin B and its analogues

1985 • 16 citations

Charge-transfer complexes of purines and pyrimidines

1968 • 16 citations

Identification of ascorbic acid as the heat-stable factor from brain which inactivates the phorbol ester receptor.

1982 • 15 citations

El Chichón Climate Effect Estimated

1983 • 14 citations

DNA alkylation and tumor induction in regenerating rat liver after cell cycle-related continuous N-nitrosodimethylamine infusion.

1983 • 13 citations

PRODUCTION OF ABNORMAL BACTERIA SOME POSSIBLE ANALOGIES WITH FORMATION OF TUMOURS

1956 • 10 citations

A novel oxidation of the carcinogen N-hydroxy-N-2-fluorenylacetamide catalyzed by peroxidase/H2O2/Br−

1985 • 10 citations

Mutagenicity of derivatives of the oncogenic purine N-oxides.

1974 • 9 citations

Oncogenicity of purine 3-oxide and unsubstituted purine in rats.

1978 • 7 citations

Comparative reactivities of esters of oncogenic and nononcogenic purine N-oxides and evidence of the oxidation-reduction reactivity of aromatic nitrenium ions.

1980 • 5 citations