Superoxide Radical: An Endogenous Toxicant

Superoxide Dismutase

1969 • 12,578 citations

SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES

1995 • 3,305 citations

How super is superoxide?

1981 • 1,294 citations

Superoxide radicals in feline intestinal ischemia

1981 • 1,213 citations

The Generation of Superoxide Radical during the Autoxidation of Hemoglobin

1972 • 1,162 citations

Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytes. An in vitro model of immune vascular damage.

1978 • 1,117 citations

Free Radicals and Inflammation: Protection of Synovial Fluid by Superoxide Dismutase

1974 • 1,109 citations

Quantitative Aspects of the Production of Superoxide Anion Radical by Milk Xanthine Oxidase

1970 • 1,037 citations

Superoxide‐dependent production of hydroxyl radical catalyzed by iron—EDTA complex

1978 • 876 citations

Ischemic injury in the cat small intestine: Role of superoxide radicals

1982 • 771 citations

A Mechanism for the Production of Ethylene from Methional

1970 • 668 citations

Superoxide radicals as precursors of mitochondrial hydrogen peroxide

1974 • 627 citations

Mechanism of the disproportionation of superoxide radicals

1977 • 466 citations

Superoxide dismutase and pulmonary oxygen toxicity

1974 • 462 citations

The scavenging of superoxide radical by manganous complexes: In vitro

1982 • 416 citations

Mechanism of the antibiotic action pyocyanine

1980 • 350 citations

Lactoferrin enhances hydroxyl radical production by human neutrophils, neutrophil particulate fractions, and an enzymatic generating system.

1981 • 338 citations

Induction of Superoxide Dismutase by Molecular Oxygen

1973 • 321 citations

Manganese, superoxide dismutase, and oxygen tolerance in some lactic acid bacteria

1981 • 319 citations

Oxygen Toxicity and the Superoxide Dismutase

1973 • 273 citations

Mutagenicity of oxygen free radicals.

1982 • 270 citations

Alloxan-induced diabetes—evidence for hydroxyl radical as a cytotoxic intermediate

1976 • 249 citations

The oxidation of phenylhydrazine: superoxide and mechanism

1976 • 221 citations

Superoxide‐dependent formation of hydroxyl radicals in the presence of thiol compounds

1982 • 214 citations

Electrostatic interactions in the reaction mechanism of bovine erythrocyte superoxide dismutase.

1982 • 213 citations

Biological defense mechanisms. Evidence for the participation of superoxide in bacterial killing by xanthine oxidase.

1975 • 202 citations

A study of the superoxide radical chemistry by stopped-flow radiolysis and radiation induced oxygen consumption

1977 • 200 citations

Initiation of Aerobic Oxidation of Sulfite by Illuminated Spinach Chloroplasts

1973 • 193 citations

Biological protection by superoxide dismutase

1973 • 179 citations

Comparison of the capacities of the perhydroxyl and the superoxide radicals to initiate chain oxidation of linoleic acid

1981 • 168 citations

Does superoxide ion oxidize catechol, .alpha.-tocopherol, and ascorbic acid by direct electron transfer?

1980 • 167 citations

Superoxide dismutase is a prophylactic against alloxan diabetes

1981 • 166 citations

Generation of superoxide anion as a source of hydrogen peroxide in a reconstituted monooxygenase system

1978 • 155 citations

Generation of a chemotactic lipid from arachidonic acid by exposure to a superoxide-generating system

1980 • 134 citations

The reaction of reduced xanthine oxidase with oxygen. Kinetics of peroxide and superoxide formation.

1981 • 134 citations

Generation of the Superoxide Radical during Autoxidation of Oxymyoglobin

1976 • 108 citations

Chemical modification of arginine at the active site of the bovine erythrocyte superoxide dismutase

1979 • 107 citations

Hypoxia and oxygen toxicity.

1979 • 103 citations

Effects of superoxide radicals on myoblast growth and differentiation

1974 • 102 citations

Molecular mechanisms of binding and single-strand scission of DNA by the antitumor antibiotics saframycins A and C

1982 • 100 citations

Inhibition by superoxide dismutase of methemoglobin formation from oxyhemoglobin.

1976 • 94 citations

Superoxide lon as the cause of the oxygen effect.

1976 • 91 citations

A new method for the detection of hydroxyl radical production by phagocytic cells

1980 • 89 citations

Oxidation by superoxide of tocopherols dispersed in aqueous media with deoxycholate

1980 • 88 citations

Effect of hydroxyl radical scavengers on microsomal oxidation of alcohols and on associated microsomal reactions

1978 • 82 citations

Relationship between superoxide dismutase and pathogenic mechanisms of Listeria monocytogenes

1979 • 82 citations

Protection of Post-irradiated Mice by Superoxide Dismutase

1976 • 80 citations

Physiological function of superoxide dismutase in glucose-limited chemostat cultures of Escherichia coli

1977 • 74 citations

Enhanced anti-inflammatory effect and reduced immunogenicity of bovine liver superoxide dismutase by conjugation with homologous albumin

1980 • 64 citations

The Role of Oxygen-Derived Free Radicals in Radiation-Induced Damage and Death of Nondividing Eucaryotic Cells

1980 • 59 citations

A reaction between the superoxide free radical and lipid hydroperoxide in sodium linoleate micelles

1982 • 50 citations

Light‐dependent ethylene production by isolated chloroplasts

1974 • 49 citations

A reaction of the superoxide radical with tetrapyrroles

1982 • 48 citations

Chromosome instability in human and murine autoimmune disease: anticlastogenic effect of superoxide dismutase.

1980 • 44 citations

Mycoplasma pneumoniae: A prokaryote which consumes oxygen and generates superoxide but which lacks superoxide dismutase

1980 • 43 citations

Superoxide production by purified hamster hepatic nuclei.

1980 • 43 citations

Production of superoxide ions in rat liver microsomes

1973 • 35 citations

Antimycin‐ and cyanide‐resistant respiration and superoxide anion production in fresh and aged potato tuber mitochondria

1978 • 35 citations

Enzymic formation of glycolate in Chromatium. Role of superoxide radical in a transketolase-type mechanism

1977 • 34 citations

Identification of ARG-143 as the essential arginyl residue in yeast Cu,Zn superoxide dismutase by use of a chromophoric arginine reagent

1980 • 32 citations

Inhibitors of superoxide dismutases: A cautionary tale

1980 • 30 citations

An inducible iron-containing superoxide dismutase in Rhizobium japonicum

1981 • 26 citations

Enzyme response of cultured endothelial cells to hyperoxia.

1981 • 19 citations

Effect of superoxide dismutase on the chromosomal instability of New Zealand black mice

1981 • 18 citations

Production of Superoxide Radicals during Bacterial Respiration

1979 • 16 citations

Electron Spin Resonance Studies on the Oxidation of Rifamycin SV Catalyzed by Metal Ions

1982 • 11 citations

The effects of interactions between sodium ascorbate and superoxide radicals generated by hypoxanthine and xanthine oxidase on 3T3 cells

1980 • 6 citations