Effects of nitric oxide synthase inhibitors, <scp>l</scp>‐N^G‐nitroarginine and <scp>l</scp>‐N^G‐nitroarginine methyl ester, on responses to vasodilators of the guinea‐pig coronary vasculature

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Role of endothelium in responses of vascular smooth muscle.

1983 • 1,975 citations

Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo

1990 • 1,869 citations

Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin.

1978 • 1,559 citations

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

1988 • 1,379 citations

Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.

1987 • 1,182 citations

The Role of Endothelium in the Responses of Vascular Smooth Muscle to Drugs

1984 • 937 citations

Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase

1987 • 896 citations

A specific inhibitor of nitric oxide formation from <scp>l</scp>‐arginine attenuates endothelium‐dependent relaxation

1989 • 862 citations

<scp>l</scp>‐N^G‐nitro arginine (<scp>l</scp>‐NOARG), a novel, <scp>l</scp>‐arginine‐reversible inhibitor of endothelium‐dependent vasodilatation in vitro

1990 • 769 citations

Stimulation of Endothelial Cell Prostacyclin Production by Thrombin, Trypsin, and the Ionophore A 23187

1978 • 715 citations

Control of coronary vascular tone by nitric oxide.

1990 • 713 citations

A novel citrulline-forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells

1989 • 612 citations

Role of endothelial cells in relaxation of isolated arteries by bradykinin.

1982 • 420 citations

Arginine is a physiological precursor of endothelium-derived nitric oxide

1988 • 392 citations

Biosynthesis of endothelium-derived relaxing factor: A cytosolic enzyme in porcine aortic endothelial cells Ca2+-dependently converts L-arginine into an activator of soluble guanylyl cyclase

1989 • 271 citations

Stimulation of Prostaglandin Biosynthesis by Adenine Nucleotides

1974 • 211 citations

5-Hydroxytryptamine can mediate endothelium-dependent relaxation of coronary arteries

1983 • 194 citations

Stimulation of prostaglandin production through purinoceptors on cultured porcine endothelial cells

1983 • 170 citations

Nitric oxide release from the isolated guinea pig heart

1988 • 153 citations

Different activation of L-arginine pathway by bradykinin, serotonin, and clonidine in coronary arteries

1990 • 109 citations

ATP mediates coronary vasoconstriction via P2x-purinoceptors and coronary vasodilatation via P2y-purinoceptors in the isolated perfused rat heart

1987 • 97 citations

L‐N^G‐nitro‐arginine and its methyl ester are potent inhibitors of non‐adrenergic, non‐cholinergic transmission in the rat anococcygeus

1990 • 97 citations

Stimulation of vascular prostacyclin synthesis by extracellular ADP and ATP

1983 • 83 citations

Release of different relaxing factors by cultured porcine endothelial cells.

1989 • 78 citations

Effects of bradykinin in the rat isolated perfused heart: role of kinin receptors and endothelium‐derived relaxing factor

1991 • 63 citations

Serotonin is localized in endothelial cells of coronary arteries and released during hypoxia: A possible new mechanism for hypoxia-induced vasodilatation of the rat heart

1988 • 56 citations

Adenosine 5′-triphosphate, adenosine and endothelium-derived relaxing factor in hypoxic vasodilatation of the heart

1989 • 52 citations

N G-nitro-l-arginine antagonizes endothelium-dependent dilator responses by inhibiting endothelium-derived relaxing factor release in the isolated rabbit heart

1991 • 51 citations

Vasodilator response of coronary smooth muscle to the sympathetic co‐transmitters noradrenaline and adenosine 5′‐triphosphate

1991 • 39 citations

The influence of atherosclerosis on the mechanical responses of human isolated coronary arteries to substance P, isoprenaline and noradrenaline

1987 • 34 citations

Effects of substance P on rate and perfusion pressure in the isolated guinea pig heart.

1990 • 34 citations

Purinoceptor mediated stimulation of prostacyclin release in the porcine pulmonary vasculature

1984 • 30 citations

Kinetics of adenine nucleotide catabolism in coronary circulation of rats

1989 • 28 citations

Effects of neurokinins on the isolated pig coronary artery

1987 • 28 citations

Evidence supporting the proposal that endothelium-derived relaxing factor is nitric oxide

1987 • 24 citations

Perfused Rabbit Heart: Endothelium-Derived Relaxing Factor in Coronary Arteries

1986 • 17 citations