Intraventricular self-administration of heroin in the rat: reward seems dissociated from analgesia and physical dependence

Nonparametric Statistics for the Behavioral Sciences

1958 • 36,277 citations

Nonparametric statistics for the behavioral sciences

1957 • 6,138 citations

Synthetic analgesics. II. Dithienylbutenyl- and dithienylbutylamines.

1953 • 1,702 citations

Self-administration of psychoactive substances by the monkey

1969 • 807 citations

Experimental Morphine Addiction: Method for Automatic Intravenous Injections in Unrestrained Rats

1962 • 638 citations

Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats

1973 • 523 citations

Enkephalin may mediate euphoria and drive-reduction reward

1977 • 450 citations

Anatomically Distinct Opiate Receptor Fields Mediate Reward and Physical Dependence

1984 • 265 citations

Reinforcing effects of brain microinjections of morphine revealed by conditioned place preference

1982 • 238 citations

Physical Dependence of Opiate-Like Peptides

1976 • 219 citations

Intravenous self-administration of drugs in rats.

1978 • 165 citations

Morphine addiction in chimpanzees.

1940 • 151 citations

Reinforcement Properties of Morphine, Cocaine, and SPA as a Function of Unit Dose

1968 • 150 citations

The transport of urea, creatinine and certain monosaccharides between blood and fluid perfusing the cerebral ventricular system of rabbits

1964 • 124 citations

Dependence creating properties of lipotropin C-fragment (β-endorphin): Evidence for its internal control of behavior

1979 • 102 citations

Oxytocin reduces intravenous heroin self-administration in heroin-tolerant rats

1985 • 83 citations

An examination of heroin conditioning in preferred and nonpreferred environments and in differentially housed mature and immature rats

1985 • 76 citations

How Opiates Change Behavior

1965 • 73 citations

Behavioral profile of ψ-MSH: Relationship with acta and β-endorphin action

1981 • 69 citations

Intraventricular self-administration of morphine in naive laboratory rats

1976 • 54 citations

Behaviorally active oxytocin fragments simultaneously attenuate heroin self-administration and tolerance in rats

1985 • 40 citations

Comparison of opioid agonists in maintaining responding and in suppressing morphine withdrawal in rhesus monkeys

1981 • 36 citations

Dose and physical dependence as factors in the self-administration of morphine by rats

1979 • 35 citations

Effect of unit dose and route of administration on self-administration of morphine

1976 • 27 citations