High‐Density Lipoprotein Aggregated by Oxidation Induces Degeneration of Neuronal Cells

Principles of Fluorescence Spectroscopy

1999 • 27,045 citations

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

1990 • 1,975 citations

The distribution of tau in the mammalian central nervous system.

1985 • 1,518 citations

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1994 • 1,313 citations

Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence

1991 • 839 citations

Apolipoprotein E: A pathological chaperone protein in patients with cerebral and systemic amyloid

1992 • 802 citations

Differential Effects of Apolipoproteins E3 and E4 on Neuronal Growth in Vitro

1994 • 797 citations

Phase fluctuation in phospholipid membranes revealed by Laurdan fluorescence

1990 • 745 citations

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro

1995 • 741 citations

β-Amyloid-mediated vasoactivity and vascular endothelial damage

1996 • 686 citations

Presence of hypochlorite-modified proteins in human atherosclerotic lesions.

1996 • 587 citations

β-Amyloid fibrils induce tau phosphorylation and loss of microtubule binding

1995 • 580 citations

Autopsy Samples of Alzheimer's Cortex Show Increased Peroxidation In Vitro

1990 • 456 citations

[8] Single vertical spin density gradient ultracentrifugation

1986 • 449 citations

Lipoprotein structure and metabolism.

1976 • 429 citations

The detection of oxidation in liposome preparations

1970 • 408 citations

Calcium-destabilizing and neurodegenerative effects of aggregated β-amyloid peptide are attenuated by basic FGF

1993 • 383 citations

Bioenergetic and oxidative stress in neurodegenerative diseases

1995 • 365 citations

Membrane lipid domains and dynamics as detected by Laurdan fluorescence

1995 • 337 citations

Morphological and biochemical maturation of neurones cultured in the absence of glial cells

1979 • 325 citations

Apolipoproteins in human cerebrospinal fluid.

1979 • 282 citations

Aggregation-related toxicity of synthetic β-amyloid protein in hippocampal cultures

1991 • 280 citations

Apolipoproteins, membrane cholesterol domains, and the regulation of cholesterol efflux.

1992 • 269 citations

Suppression of MAP2 in cultured cerebeller macroneurons inhibits minor neurite formation

1992 • 255 citations

Biophysical consequences of lipid peroxidation in membranes

1987 • 250 citations

Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit.

1989 • 250 citations

Methodological variables in the assessment of beta amyloid neurotoxicity

1992 • 208 citations

Brain Expression of Apolipoproteins E, J, and A‐I in Alzheimer's Disease

1996 • 174 citations

Characterization of subpopulations of lipoprotein particles isolated from human cerebrospinal fluid

1995 • 156 citations

Microtubule-associated protein 1b (MAP1b) is concentrated in the distal region of growing axons

1994 • 152 citations

Binding of high density lipoprotein to cultured fibroblasts after chemical alteration of apoprotein amino acid residues.

1986 • 122 citations

Apolipoprotein A1-derived amyloid in human aortic atherosclerotic plaques.

1995 • 111 citations

A New Low Density Lipoprotein Receptor Homologue with 8 Ligand Binding Repeats in Brain of Chicken and Mouse

1996 • 106 citations

Alzheimer paired helical filaments: Immunochemical identification of polypeptides

1984 • 104 citations

Absence of lipid gel-phase domains in seven mammalian cell lines and in four primary cell types

1993 • 103 citations

Expression of transfected human CuZn superoxide dismutase gene in mouse L cells and NS20Y neuroblastoma cells induces enhancement of glutathione peroxidase activity

1988 • 96 citations

Down syndrome and Alzheimer disease.

1992 • 89 citations

Synthesis of apolipoprotein AI by peripheral tissues of the rooster. A possible mechanism of cellular cholesterol efflux.

1982 • 86 citations

X-ray diffraction evidence for myelin disorder in brain from humans with alzheimer's disease

1984 • 85 citations

Physicochemical changes in human high-density lipoproteins (HDL) oxidized by gamma radiolysis-generated oxyradicals. Effect on their cholesterol effluxing capacity

1995 • 75 citations

Expression of Apolipoprotein A‐I in Porcine Brain Endothelium In Vitro

1994 • 74 citations

Induction of rat E and chicken A-I apolipoproteins and mRNAs during optic nerve degeneration.

1986 • 69 citations

Membrane aging during cell growth ascertained by laurdan generalized polarization

1992 • 68 citations

Acetylated low density lipoprotein reduces its ligand activity for the scavenger receptor after interaction with reconstituted high density lipoprotein.

1994 • 67 citations

Evidence for an Increase in Water Concentration in Bilayers after Oxidative Damage of Phospholipids Induced by Ionizing Radiation

1994 • 66 citations

Hemoglobin Induced Apolipoprotein B Crosslinking in Low-Density Lipoprotein Peroxidation

1996 • 62 citations

Ischemia and hypoxia

1989 • 57 citations

Optic Nerve Regeneration in Adult Fish and Apolipoprotein A‐I

1989 • 56 citations

Expression of human apolipoprotein A-I epitopes in high density lipoproteins and in serum.

1987 • 56 citations

Reduced Cholesterol Efflux to Mildly Oxidized High Density Lipoprotein

1994 • 51 citations

In vitro oxidised HDL is recognised by the scavenger receptor of macrophages: implications for its protective role in vivo

1994 • 49 citations

Auto-oxidation-induced fusion of lipid vesicles

1982 • 43 citations

High-density lipoprotein and cerebral endothelial cells in vitro: Interactions and transport

1995 • 40 citations

Leakage and neuronal uptake of serum protein in aged and Alzheimer brains. A postmortem phenomenon with antemortem etiology.

1991 • 39 citations

Lipid Peroxidation Changes the Expression of Specific Epitopes of Apolipoprotein A-I

1989 • 39 citations

Characterization of dietary-induced hypercholesterolemia in the chicken

1992 • 38 citations

Synthesis and secretion of apolipoprotein A1 by chick breast muscle.

1983 • 37 citations

Properties of rooster serum high density lipoproteins

1975 • 36 citations

Chicken apolipoprotein A-I: cDNA sequence, tissue expression and evolution

1987 • 33 citations

The complete sequence of chick apolipoprotein AI mRNA and its expression in the developing chick

1987 • 32 citations

High-density lipoprotein 3 physicochemical modifications induced by interaction with human polymorphonuclear leucocytes affect their ability to remove cholesterol from cells

1996 • 27 citations

Apolipoprotein-lipid association in oxidatively modified HDL and LDL

1994 • 26 citations

Modified apolipoprotein pattern after irradiation of human high-density lipoproteins by ultraviolet B

1992 • 23 citations

Physical, chemical, and immunochemical studies of apolipoprotein A-I from pigeon plasma high density lipoproteins

1980 • 15 citations

High‐Density Lipoprotein Inhibits UDP‐N‐Acetylgalactosamine:GM3,N‐Acetylgalactosaminyltransferase and Differentiation of Cultured Cerebral Cells: Comparison with a Formerly Described Inhibitor of This Enzyme

1995 • 8 citations