Role of Selective Leptin Resistance in Diet-Induced Obesity Hypertension

Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans

1996 • 6,254 citations

Leptin and the regulation of body weight in mammals

1998 • 5,366 citations

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

1995 • 3,730 citations

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

1996 • 1,170 citations

Receptor-mediated regional sympathetic nerve activation by leptin.

1997 • 980 citations

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

2000 • 873 citations

The Kidney, Hypertension, and Obesity

2003 • 856 citations

Region-Specific Leptin Resistance within the Hypothalamus of Diet-Induced Obese Mice

2004 • 716 citations

Chronic Leptin Infusion Increases Arterial Pressure

1998 • 694 citations

Sympathetic Neural Activation in Visceral Obesity

2002 • 549 citations

Pathophysiological role of leptin in obesity-related hypertension

2000 • 479 citations

Intracerebroventricular Leptin Increases Lumbar and Renal Sympathetic Nerve Activity and Blood Pressure in Normal Rats

1997 • 418 citations

Regional Sympathetic Nervous Activity and Oxygen Consumption in Obese Normotensive Human Subjects

1997 • 403 citations

Renal Denervation Attenuates the Sodium Retention and Hypertension Associated With Obesity

1995 • 307 citations

Chronic Cardiovascular and Renal Actions of Leptin

2002 • 285 citations

Interactions Between Leptin and the Human Sympathetic Nervous System

2003 • 281 citations

Contrasting blood pressure effects of obesity in leptin-deficient ob/ob mice and agouti yellow obese mice

1999 • 245 citations

The Concept of Selective Leptin Resistance

2002 • 221 citations

Hypertension and Obesity

2004 • 219 citations

Role of sympathetic nervous system and neuropeptides in obesity hypertension

2000 • 151 citations

The Sympathetic Nervous System and Hypertension

2004 • 151 citations

Cardiovascular Responses Evoked by Leptin Acting on Neurons in the Ventromedial and Dorsomedial Hypothalamus

2003 • 136 citations

Attenuation of leptin-mediated effects by monosodium glutamate-induced arcuate nucleus damage

1997 • 134 citations

Selective Resistance to Central Neural Administration of Leptin in Agouti Obese Mice

2002 • 129 citations

Interaction between leptin and sympathetic nervous system in hypertension

2000 • 121 citations

High fat feeding is associated with increased blood pressure, sympathetic nerve activity and hypothalamic mu opioid receptors

2003 • 87 citations

Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats

1997 • 81 citations

The arcuate nucleus is pivotal in mediating the anorectic effects of centrally administered leptin

1999 • 68 citations

Leptin injection into white adipose tissue elevates renal sympathetic nerve activity dose-dependently through the afferent nerves pathway in rats

2000 • 63 citations

Obesity due to high fat diet decreases the sympathetic nervous and cardiovascular responses to intracerebroventricular leptin in rats

1998 • 57 citations

Direct measurement of renal sympathetic nervous activity in high-fat diet-related hypertensive rats

2002 • 50 citations