Quantitation of the Cell Surface Level of Ld Resulting in Positive Versus Negative Selection of the 2C Transgenic T Cell Receptor In Vivo

Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide

1963 • 7,266 citations

T cell receptor antagonist peptides induce positive selection

1994 • 2,818 citations

β2-Microglobulin deficient mice lack CD4−8+ cytolytic T cells

1990 • 997 citations

Normal Development of Mice Deficient in β ₂ M, MCClass I Proteins, and CD8 ⁺ T Cells

1990 • 885 citations

Positive and negative selection of an antigen receptor on T cells in transgenic mice

1988 • 758 citations

Evidence for a differential avidity model of T cell selection in the thymus

1994 • 679 citations

Positive Selection of Thymocytes

1995 • 604 citations

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

1988 • 505 citations

Positive and Negative Thymocyte Selection Induced by Different Concentrations of a Single Peptide

1994 • 497 citations

A naturally occurring peptide recognized by alloreactive CD8+ cytotoxic T lymphocytes in association with a class I MHC protein

1992 • 286 citations

Thymic selection: a matter of life and death

1992 • 184 citations

Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding.

1990 • 170 citations

Strong agonist ligands for the T cell receptor do not mediate positive selection of functional CD8+ T cells

1995 • 161 citations

Peptides in positive and negative selection: A delicate balance

1994 • 153 citations

Mature T cell reactivity altered by peptide agonist that induces positive selection.

1996 • 148 citations

The CD8+ T cell repertoire in beta 2-microglobulin-deficient mice is biased towards reactivity against self-major histocompatibility class I.

1994 • 97 citations

Evidence for a single-niche model of positive selection.

1994 • 76 citations

Highly lytic CD8+, alpha beta T-cell receptor cytotoxic T cells with major histocompatibility complex (MHC) class I antigen-directed cytotoxicity in beta 2-microglobulin, MHC class I-deficient mice.

1993 • 67 citations

Development and antigen specificity of CD8+ cytotoxic T lymphocytes in beta 2-microglobulin-negative, MHC class I-deficient mice in response to immunization with tumor cells.

1994 • 41 citations

Induction of peptide-specific CD8+ CTL clones in beta 2-microglobulin-deficient mice.

1995 • 30 citations

Automated synthesis of a C-terminal photoprobe using combined Fmoc and t-Boc synthesis strategies on a single automated peptide synthesizer.

1989 • 27 citations

CD4+ and CD8+ alpha beta, and gamma delta T cells are cytotoxic effector cells of beta 2-microglobulin-deficient mice against cells having normal MHC class I expression.

1994 • 15 citations