Drotrecogin Alfa (activated) Prevents Smoke-Induced Increases in Pulmonary Microvascular Permeability and Proinflammatory Cytokine IL-1β in Rats

Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis

2001 • 5,900 citations

High-Dose Corticosteroids in Patients with the Adult Respiratory Distress Syndrome

1987 • 881 citations

The Effects of High-Dose Corticosteroids in Patients with Septic Shock

1984 • 761 citations

Ineffectiveness of High-dose Methylprednisolone in Preventing Parenchymal Lung Injury and Improving Mortality in Patients with Septic Shock

1988 • 511 citations

Tumor Necrosis Factor Suppresses Transcription of the Thrombomodulin Gene in Endothelial Cells

1988 • 367 citations

Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells.

1988 • 284 citations

Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats

1996 • 252 citations

The neuropeptide substance P activates transcription factor NF-kappa B and kappa B-dependent gene expression in human astrocytoma cells.

1997 • 192 citations

Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammation

2001 • 187 citations

Metalloproteolytic Release of Endothelial Cell Protein C Receptor

2000 • 184 citations

Toxic Gases from Fires

1978 • 145 citations

Intratracheal Administration of Activated Protein C Inhibits Bleomycin-induced Lung Fibrosis in the Mouse

2001 • 142 citations

Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice

2003 • 100 citations

SMOKE AND CARBON MONOXIDE POISONING IN FIRE VICTIMS

1972 • 99 citations

Regulation and functions of the protein C anticoagulant pathway.

1999 • 92 citations

Transient increase of serum Clara cell protein (CC16) after exposure to smoke.

1997 • 90 citations

Impact of haze from forest fire to respiratory health: Indonesian experience

2000 • 82 citations

Effect of substance P on superoxide anion and IL-8 production by human PMNL.

1994 • 74 citations

Protein C Anticoagulant System in Patients with Interstitial Lung Disease

1998 • 71 citations

Activation of Protein C Pathway in the Airways

2002 • 69 citations

A Correlation of Experimental and Clinical Data

1977 • 60 citations

Participation of fast-activating, voltage-dependent K currents in electrical slow waves of colonic circular muscle

1992 • 58 citations

Substance P induces secretion of immunomodulatory cytokines by human astrocytoma cells

1998 • 49 citations

A murine model of smoke inhalation

2001 • 40 citations

Acute Lung Injury, Acute Respiratory Distress Syndrome and Inhalation Injury: An Overview

1999 • 38 citations

Decreased Protein C Activation Is Associated With Abnormal Collagen Turnover in the Intraalveolar Space of Patients With Interstitial Lung Disease

2000 • 36 citations

Detection of acute inhalation injury in fire victims by means of technetium-99m DTPA radioaerosol inhalation lung scintigraphy

1997 • 34 citations

Bronchial epithelial cells release neutrophil chemotactic activity in response to tachykinins

1992 • 30 citations

Smoke inhalation injury

1987 • 28 citations

Bronchoalveolar lavage findings in firefighters

1997 • 24 citations

Pulmonary toxicity in hamsters of smoke particles from Kuwaiti oil fires.

1998 • 21 citations

Severe Obstructive Lung Disease after Smoke Inhalation

1979 • 19 citations

Immunomodulatory effects of high-dose α-tocopherol acetate on mice subjected to sidestream cigarette smoke

2002 • 19 citations

Role of Activated Protein C inHelicobacter pylori-Associated Gastritis

2000 • 18 citations

Pulmonary complications in burn patients.

1983 • 17 citations

Age-related differences in pulmonary inflammatory responses to JP-8 jet fuel aerosol inhalation

2001 • 16 citations

Early Alterations of Lung Injury Following Acute Smoke Exposure and 21-Aminosteroid Treatment

1999 • 14 citations

The Prophylactic Effects of U75412E Pretreatment in a Smoke‐Induced Lung Injury Rabbit Model

1996 • 9 citations

Pre-hospital strategy for therapeutic intervention of fire victims

1992 • 8 citations