Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats

Control of vascular permeability by polymorphonuclear leukocytes in inflammation

1981 • 850 citations

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.

1987 • 836 citations

THE ROLE OF ENDOTHELIAL CELLS IN INFLAMMATION

1990 • 808 citations

Septic Shock, Multiple Organ Failure, and Disseminated Intravascular Coagulation

1992 • 708 citations

The inhibition of blood coagulation by activated protein C through the selective inactivation of activated factor V

1979 • 480 citations

Neutrophil-dependent acute lung injury. Requirement for P-selectin (GMP-140).

1992 • 385 citations

The protein C anticoagulant pathway.

1992 • 293 citations

Inflammation and Coagulation: Linked Processes Potentially Regulated Through a Common Pathway Mediated by Protein C

1991 • 261 citations

Intravascular coagulation associated with the adult respiratory distress syndrome

1976 • 254 citations

Human Protein C inhibits selectin-mediated cell adhesion: role of unique fucosylated oligosaccharide

1994 • 233 citations

Tumor necrosis factor participates in the pathogenesis of acute immune complex alveolitis in the rat.

1989 • 207 citations

Disseminated intravascular coagulation in rabbits induced by administration of endotoxin or tissue factor: effect of anti-tissue factor antibodies and measurement of plasma extrinsic pathway inhibitor activity

1990 • 199 citations

Reperfusion-induced leukocyte infiltration: role of elastase

1990 • 137 citations

Immunologic Therapy for ARDS, Septic Shock, and Multiple-Organ Failure

1993 • 103 citations

Role of the Coagulation System in ARDS

1994 • 73 citations

Attenuation of Tumor Necrosis Factor-induced Endothelial Cell Cytotoxicity and Neutrophil Chemiluminescence

1990 • 69 citations

Treatment of patients with disseminated intravascular coagulation by protein C

1990 • 54 citations

Membrane-bound enzyme complexes in blood coagulation.

1984 • 49 citations

Role of leukocytes in the activation of intravascular coagulation in patients with septicemia

1991 • 43 citations

Inhibitory effects of activated protein C and heparin on thrombotic arterial occlusion in rat mesenteric arteries

1991 • 33 citations

Heparin oligosaccharides bind L- and P-selectin and inhibit acute inflammation

1993 • 32 citations

Characteristic effects of activated human protein C on tissue thromboplastin-induced disseminated intravascular coagulation in rabbits

1994 • 29 citations

Thrombin-Induced Intravascular Coagulation: Role in Vascular Injury

1987 • 27 citations

Inhibition of Microarterial Thrombosis by Activated Protein C in a Rabbit Model

1994 • 25 citations

Tumor necrosis factor-induced lung injury is not mediated by platelet-activating factor

1989 • 14 citations

DEGR-factor Xa blocks disseminated intravascular coagulation initiated by Escherichia coli without preventing shock or organ damage

1991 • 8 citations

Adult Respiratory Distress Syndrome

1993 • 3 citations