Reciprocal cross-desensitization of locus coeruleus electrophysiological responsivity to corticotropin-releasing factor and stress

Characterization of a 41-Residue Ovine Hypothalamic Peptide that Stimulates Secretion of Corticotropin and β-Endorphin

1982 • 3,896 citations

The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis

1992 • 3,026 citations

The Concepts of Stress and Stress System Disorders

1992 • 2,419 citations

Organization of Ovine Corticotropin-Releasing Factor Immunoreactive Cells and Fibers in the Rat Brain: An Immunohistochemical Study

1983 • 1,954 citations

Nucleus locus ceruleus: new evidence of anatomical and physiological specificity

1983 • 1,877 citations

Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

1984 • 1,490 citations

Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

1990 • 1,362 citations

Localization of novel corticotropin-releasing factor receptor (CRF2) mRNA expression to specific subcortical nuclei in rat brain: comparison with CRF1 receptor mRNA expression

1995 • 917 citations

Mechanisms of stress: A dynamic overview of hormonal and behavioral homeostasis

1992 • 867 citations

Impulse activity of locus coeruleus neurons in awake rats and monkeys is a function of sensory stimulation and arousal.

1980 • 836 citations

Corticotropin releasing factor produces behavioural activation in rats

1982 • 752 citations

Corticotropin-releasing factor activates noradrenergic neurons of the locus coeruleus

1983 • 595 citations

Reduced Corticotropin Releasing Factor Binding Sites in the Frontal Cortex of Suicide Victims

1988 • 547 citations

Modulation of stress-induced ACTH release by corticotropin-releasing factor, catecholamines and vasopressin

1983 • 535 citations

Corticotropin-releasing factor receptors are widely distributed within the rat central nervous system: an autoradiographic study

1985 • 474 citations

Corticotropin-releasing factor immunoreactivity is widely distributed within the central nervous system of the rat: an immunohistochemical study

1983 • 419 citations

Single-unit response of noradrenergic neurons in the locus coeruleus of freely moving cats. I. Acutely presented stressful and nonstressful stimuli

1987 • 374 citations

Induction and habituation of immediate early gene expression in rat brain by acute and repeated restraint stress

1994 • 357 citations

Characterization of hippocampal norepinephrine release as measured by microdialysis perfusion: Pharmacological and behavioral studies

1988 • 345 citations

Stress and the hypothalamo-pituitary-adrenal axis: acute, chronic and immunological activation

1992 • 336 citations

CRF antagonist partially reverses CRF- and stress-induced effects on feeding

1986 • 302 citations

Activation of noradrenergic locus coeruleus neurons by hemodynamic stress is due to local release of corticotropin-releasing factor

1991 • 247 citations

Corticotropin releasing factor (CRF)-like immunoreactivity in the rat central nervous system. Extrahypothalamic distribution

1984 • 243 citations

Prior exposure to chronic stress results in enhanced synthesis and release of hippocampal norepinephrine in response to a novel stressor

1991 • 237 citations

Corticotropin-releasing hormone increases tonic but not sensory-evoked activity of noradrenergic locus coeruleus neurons in unanesthetized rats

1988 • 221 citations

Corticotropin-releasing factor innervation of the locus coeruleus region: Distribution of fibers and sources of input

1992 • 219 citations

Corticotropin-releasing factor: long-lasting facilitation of the acoustic startle reflex

1992 • 205 citations

Corticotropin-Releasing Factor Receptors and Pituitary Adrenal Responses during Immobilization Stress

1988 • 200 citations

Brain and pituitary receptors for corticotropin releasing factor: Localization and differential regulation after adrenalectomy

1984 • 196 citations

CRF receptor regulation and sensitization of ACTH responses to acute ether stress during chronic intermittent immobilization stress

1990 • 191 citations

Corticotropin-releasing factor modulates defensive-withdrawal and exploratory behavior in rats.

1989 • 190 citations

Increased tyrosine hydroxylase activity in the locus coeruleus of rat brain stem after reserpine treatment and cold stress

1974 • 186 citations

Regulation of locus coeruleus neurons and splanchnic, sympathetic nerves by cardiovascular afferents

1984 • 176 citations

Corticotropin-releasing factor modulates defensive-withdrawal and exploratory behavior in rats.

1989 • 171 citations

Involvement of corticotropin-releasing factor in chronic stress regulation of the brain noradrenergic system.

1991 • 171 citations

Single-unit response of noradrenergic neurons in the locus coeruleus of freely moving cats. II. Adaptation to chronically presented stressful stimuli

1987 • 166 citations

Potentiation of acoustic startle by corticotropin-releasing factor (CRF) and by fear are both reversed by ?-helical CRF (9?41)

1989 • 159 citations

Corticotropin-releasing factor antagonist blocks stress-induced fighting in rats

1987 • 148 citations

CRF-induced seizures and behavior: Interaction with amygdala kindling

1986 • 148 citations

Water-avoidance stress-inducedc-fos expression in the rat brain and stimulation of fecal output: role of corticotropin-releasing factor

1994 • 147 citations

Activating and ‘anxiogenic’ effects of corticotropin releasing factor are not inhibited by blockade of the pituitary-adrenal system with dexamethasone

1986 • 145 citations

Effects of corticotropin releasing factor on locomotor activity in hypophysectomized rats

1985 • 145 citations

Stress-Induced Secretion of Adrenocorticotropin in Rats Is Inhibited by Administration of Antisera to Ovine Corticotropin-Releasing Factor and Vasopressin*

1985 • 126 citations

Antagonism of endogenous CRH systems attenuates stress-induced freezing behavior in rats

1988 • 126 citations

Effects of stress and adrenalectomy on tyrosine hydroxylase mRNA levels in the locus ceruleus by in situ hybridization

1991 • 125 citations

Direct Evidence for Chronic Stress-Induced Facilitation of the Adrenocorticotropin Response to a Novel Acute Stressor

1994 • 120 citations

A corticotropin-releasing factor antagonist reverses the stress-induced changes of exploratory behavior in mice

1987 • 118 citations

Corticotropin-releasing hormone and pituitary-adrenocortical responses in chronically stressed rats

1988 • 110 citations

Induction and habituation of c-fos and zif/268 by acute and repeated stressors

1994 • 102 citations

Previous stress alters corticotropin-releasing factor neurotransmission in the locus coeruleus

1995 • 100 citations

Effects of physiological manipulations on locus coeruleus neuronal activity in freely moving cats. II. Cardiovascular challenge

1987 • 97 citations

Stimulation of the locus coeruleus decreases arterial pressure

1987 • 96 citations

Chronic stress-induced changes in locus coeruleus neuronal activity

1990 • 95 citations

Stress, antidepressant drugs, and the locus coeruleus

1994 • 85 citations

CRF initiates biological actions within the brain that are observed in response to stress

1987 • 85 citations

Dissociation between in vivo hippocampal norepinephrine response and behavioral/neuroendocrine responses to noise stress in rats

1992 • 84 citations

ICV-CRH alters stress-induced freezing behavior without affecting pain sensitivity

1988 • 83 citations

Antagonism of corticotropin-releasing factor receptors in the locus coeruleus attenuates shock-induced freezing in rats

1992 • 75 citations

Repeated stress reduces the subsequent stress-induced expression of Fos in rat brain

1994 • 73 citations

Chemical stimulation of the locus coeruleus: inhibitory effects on hemodynamics and renal sympathetic nerve activity

1991 • 68 citations

The effects of corticotrophin releasing factor (CRF) and handling stress on behavior in the elevated plus-maze test of anxiety

1991 • 66 citations

The effect of repeated mild stress on cerebral cortical adrenoceptors and noradrenaline synthesis in the rat

1984 • 66 citations

Effects of Single or Repeated Immobilization on Release of Norepinephrine and Its Metabolites in the Central Nucleus of the Amygdala in Conscious Rats

1993 • 63 citations

Corticotropin-releasing factor and angiotensin II: Comparison of CNS actions to influence neuroendocrine and cardiovascular function

1984 • 62 citations

Effects of chronic stress on anterior pituitary and brain corticotropin-releasing factor receptors

1993 • 59 citations

High intracerebral levels of CRH result in CRH receptor downregulation in the amygdala and neuroimmune desensitization

1993 • 56 citations

Corticotropin-releasing factor in olivocerebellar climbing-fiber system of monkey (Saimiri sciureus and Macaca fascicularis): parasagittal and regional organization visualized by immunohistochemistry

1988 • 50 citations

Chronic stress attenuation of α2-adrenoceptor reactivity is reversed by naltrexone

1988 • 47 citations

A CRF antagonist attenuates stress-induced increases in NA turnover in extended brain regions in rats

1993 • 44 citations

Corticotropin-releasing factor: putative neurotransmitter in the noradrenergic nucleus locus ceruleus.

1989 • 44 citations

CRF receptor antagonist attenuates stress-induced noradrenaline release in the medial prefrontal cortex of rats

1994 • 42 citations

Effects of pretreatment with corticotropin-releasing factor on the electrophysiological responsivity of the locus coeruleus to subsequent corticotropin-releasing factor challenge

1995 • 34 citations

Chemical stimulation of the nucleus locus coeruleus: cardiovascular responses and baroreflex modification

1993 • 33 citations

Dissociation of locus coeruleus activity and blood pressure

1986 • 33 citations

Time course effects of uncontrollable stress in locus coeruleus neuronal activity

1991 • 32 citations

Effects of blood pressure changes on the catecholamine release in the locus coeruleus of cats anaesthetized with pentobarbital or chloralose

1993 • 25 citations

Central corticotropin releasing factor reduces natural cytotoxicity Time course of action

1989 • 24 citations

The effect of two different types of stress on locus coeruleus alpha-2 receptor binding

1994 • 24 citations

EEG stability following corticotropin releasing factor in rats

1986 • 22 citations

Effects of repeated administration of corticotropin-releasing factor on schedule-controlled behavior in rats

1993 • 8 citations