Spinal administration of capsazepine inhibits noxious evoked responses of dorsal horn neurons in non-inflamed and carrageenan inflamed rats

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1997 • 8,634 citations

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

1988 • 4,963 citations

Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor

2000 • 3,436 citations

The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

1998 • 3,026 citations

Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

1999 • 2,128 citations

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

2000 • 1,715 citations

The Vanilloid Receptor: A Molecular Gateway to the Pain Pathway

2001 • 1,532 citations

Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances

2000 • 1,048 citations

Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X₃ purinoceptor and IB4 binding sites

1999 • 835 citations

Induction of vanilloid receptor channel activity by protein kinase C

2000 • 814 citations

The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1)

2000 • 766 citations

Glass-coated platinum-plated tungsten microelectrodes

1972 • 610 citations

Prostaglandins and cycloxygenases in the spinal cord

2001 • 413 citations

Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurones in the rat

1990 • 310 citations

Cyclooxygenase inhibition and the spinal release of prostaglandin E2 and amino acids evoked by paw formalin injection: a microdialysis study in unanesthetized rats

1995 • 305 citations

The cAMP Transduction Cascade Mediates the Prostaglandin E₂Enhancement of the Capsaicin-Elicited Current in Rat Sensory Neurons: Whole-Cell and Single-Channel Studies

1998 • 295 citations

Antihyperalgesic effects of spinal cannabinoids

1998 • 282 citations

Cannabinoid CB1 Receptor Expression in Rat Spinal Cord

2000 • 257 citations

Capsazepine block of voltage‐activated calcium channels in adult rat dorsal root ganglion neurones in culture

1997 • 256 citations

The vanilloid receptor (VR1)‐mediated effects of anandamide are potently enhanced by the cAMP‐dependent protein kinase

2001 • 205 citations

Anandamide Excites Central Terminals of Dorsal Root Ganglion Neurons via Vanilloid Receptor-1 Activation

2001 • 194 citations

Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in capsaicin‐induced antinociception

1991 • 151 citations

Axonal transport of VR1 capsaicin receptor mRNA in primary afferents and its participation in inflammation‐induced increase in capsaicin sensitivity

2001 • 139 citations

Vanilloid receptor VR1 is both presynaptic and postsynaptic in the superficial laminae of the rat dorsal horn

2001 • 139 citations

Inflammatory Mediators at Acidic pH Activate Capsaicin Receptors in Cultured Sensory Neurons From Newborn Rats

1998 • 112 citations

Release of glutamate, nitric oxide and prostaglandin E2 and metabolic activity in the spinal cord of rats following peripheral nociceptive stimulation

2001 • 96 citations

Electrophysiologic Analysis of Preemptive Effects of Spinal Opioids on N-methyl-D-aspartate Receptor-mediated Events

1994 • 70 citations

Synaptic activation of dorsal horn neurons by selective C-fibre excitation with capsaicin in the mouse spinal cord in vitro

1992 • 47 citations

Spinal anandamide inhibits nociceptive transmission via cannabinoid receptor activation in vivo

2000 • 40 citations

The analgesia induced by intrathecal injection of ruthenium red

1993 • 10 citations