Effects of MK801 and neuroleptics on prepulse inhibition: re-examination in two strains of rats

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The rat brain in stereotaxic coordinates

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Sensorimotor Gating and Schizophrenia

1990 • 1,307 citations

The neurobiology of startle

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Gating and Habituation of the Startle Reflex in Schizophrenic Patients

1992 • 1,030 citations

Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

1994 • 860 citations

Assessing the Validity of an Animal Model of Deficient Sensorimotor Gating in Schizophrenic Patients

1994 • 702 citations

Dopaminergic stimulation disrupts sensorimotor gating in the rat

1988 • 609 citations

Startle response models of sensorimotor gating and habituation deficits in schizophrenia

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Animal models of deficient sensorimotor gating: what we know, what we think we know, and what we hope to know soon

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The neural substrates of sensorimotor gating of the startle reflex: a review of recent findings and their implications

1992 • 394 citations

Effects of phencyclidine and phencyclidine biologs on sensorimotor gating in the rat*1

1989 • 375 citations

A selective imaging of tinnitus

1999 • 342 citations

Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response.

1994 • 334 citations

Examination of drug-induced and isolation-induced disruptions of prepulse inhibition as models to screen antipsychotic drugs

1995 • 231 citations

Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine

1995 • 194 citations

Failure of haloperidol to block the effects of phencyclidine and dizocilpine on prepulse inhibition of startle

1991 • 189 citations

Clozapine and haloperidol in an animal model of sensorimotor gating deficits in schizophrenia

1993 • 189 citations

Multiple limbic regions mediate the disruption of prepulse inhibition produced in rats by the noncompetitive NMDA antagonist dizocilpine.

1998 • 165 citations

Toward Understanding the Biology of a Complex Phenotype: Rat Strain and Substrain Differences in the Sensorimotor Gating-Disruptive Effects of Dopamine Agonists

2000 • 162 citations

Seroquel restores sensorimotor gating in phencyclidine-treated rats.

1996 • 156 citations

Multiple Limbic Regions Mediate the Disruption of Prepulse Inhibition Produced in Rats by the Noncompetitive NMDA Antagonist Dizocilpine

1998 • 148 citations

Prepulse inhibition of acoustic startle, a measure of sensorimotor gating: Effects of antipsychotics and other agents in rats

1995 • 145 citations

Seroquel, clozapine and chlorpromazine restore sensorimotor gating in ketamine-treated rats

1998 • 131 citations

Role of dopamine in prepulse inhibition of acoustic startle

2000 • 126 citations

Strain differences in the isolation-induced effects on prepulse inhibition of the acoustic startle response and on locomotor activity.

2000 • 104 citations

The effects of haloperidol and clozapine on the disruption of sensorimotor gating induced by the noncompetitive glutamate antagonist MK-801

1993 • 99 citations

Discrepant Findings of Clozapine Effects on Prepulse Inhibition of Startle: Is It the Route or the Rat?

1998 • 88 citations

Prepulse inhibition as a screening test for potential antipsychotics

1991 • 83 citations

Rat Strain Differences in the Ability to Disrupt Sensorimotor Gating Are Limited to the Dopaminergic System, Specific to Prepulse Inhibition, and Unrelated to Changes in Startle Amplitude or Nucleus Accumbens Dopamine Receptor Sensitivity

1999 • 82 citations

The atypical antipsychotic, remoxipride, blocks phencyclidine-induced disruption of prepulse inhibition in the rat

1994 • 79 citations

Differences between three rat strains in sensitivity to prepulse inhibition of an acoustic startle response: influence of apomorphine and phencyclidine pretreatment

1994 • 78 citations

The ventral subiculum modulation of prepulse inhibition is not mediated via dopamine D2 or nucleus accumbens non-NMDA glutamate receptor activity

1996 • 61 citations

Amygdaloid N-methyl-d-aspartate and γ-aminobutyric acidA receptors regulate sensorimotor gating in a dopamine-dependent way in rats

2000 • 57 citations

Alpha-1-adrenergic receptors mediate sensorimotor gating deficits produced by intracerebral dizocilpine administration in rats

1999 • 52 citations

Induction of Fos-protein in the forebrain and disruption of sensorimotor gating following N-methyl-d-aspartate infusion into the ventral hippocampus of the rat

1998 • 50 citations

Microinfusion of the non-competitive N-methyl-d-aspartate receptor antagonist MK-801 (dizocilpine) into the dorsal hippocampus of Wistar rats does not affect latent inhibition and prepulse inhibition, but increases startle reaction and locomotor activity

2000 • 37 citations

Disruption of prepulse inhibition following N-methyl-D-aspartate infusion into the ventral hippocampus is antagonized by clozapine but not by haloperidol

1999 • 37 citations

The effects of subchronic haloperidol on intact and dizocilpine-disrupted sensorimotor gating

1999 • 32 citations

A topographic event-related potential follow-up study on `prepulse inhibition' in first and second episode patients with schizophrenia

1999 • 30 citations

Clozapine's effects on phencyclidine-induced disruption of prepulse inhibition of the acoustic startle response

1994 • 30 citations

Quantitative autoradiographic localization of [3H]3-OH-PCP (1-(1(3-Hydroxyphenyl)cyclohexyl)piperidine) binding sites in rat brain

1995 • 12 citations