Role of dopamine in prepulse inhibition of acoustic startle

Gating and Habituation of the Startle Reflex in Schizophrenic Patients

1992 • 1,030 citations

Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system processes sensory input.

1980 • 783 citations

Dopaminergic stimulation disrupts sensorimotor gating in the rat

1988 • 609 citations

Startle response models of sensorimotor gating and habituation deficits in schizophrenia

1990 • 457 citations

Central dopamine hyperactivity in rats mimics abnormal acoustic startle response in schizophrenics

1986 • 341 citations

A self-rating to measure subjective effects of neuroleptic drugs, relationships to objective psychopathology, quality of life, compliance and other clinical variables

1995 • 308 citations

Amphetamine‐Induced Dopamine Release in the Rat Striatum: An In Vivo Microdialysis Study

1988 • 291 citations

Amphetamine, cocaine, and fencamfamine: relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics

1991 • 289 citations

Schizophrenic-like sensorimotor gating abnormalities in rats following dopamine infusion into the nucleus accumbens

1990 • 248 citations

Effects of spiperone, raclopride, SCH 23390 and clozapine on apomorphine inhibition of sensorimotor gating of the startle response in the rat.

1991 • 247 citations

Amphetamine disruption of prepulse inhibition of acoustic startle is reversed by depletion of mesolimbic dopamine

1990 • 233 citations

Cocaine: An in vivo microdialysis evaluation of its acute action on dopamine transmission in rat striatum

1989 • 218 citations

Management of the Adverse Effects of Clozapine

1998 • 207 citations

Adverse effects of stimulant drugs in a community sample of drug users

1997 • 201 citations

Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine

1995 • 194 citations

Clozapine and haloperidol in an animal model of sensorimotor gating deficits in schizophrenia

1993 • 189 citations

Is stimulation of both D1 and D2 receptors necessary for the expression of dopamine-mediated behaviors?

1988 • 177 citations

Prepulse inhibition of acoustic startle, a measure of sensorimotor gating: Effects of antipsychotics and other agents in rats

1995 • 145 citations

Olanzapine versus haloperidol in the treatment of schizophrenia and other psychotic disorders: quality of life and clinical outcomes of a randomized clinical trial.

1999 • 139 citations

A D2 dopamine receptor agonist disrupts sensorimotor gating in rats. Implications for dopaminergic abnormalities in schizophrenia.

1990 • 138 citations

Permissive role of D-1 receptor stimulation for the expression of D-2 mediated behavioral responses: a quantitative phenomenological study in rats

1987 • 115 citations

The effects of haloperidol and clozapine on the disruption of sensorimotor gating induced by the noncompetitive glutamate antagonist MK-801

1993 • 99 citations

Ca2+ dependence of the amphetamine, nomifensine, and Lu 19-005 effect on in vivo dopamine transmission

1989 • 96 citations

Neuroleptics and the neuroleptic‐induced deficit syndrome

1994 • 96 citations

Discrepant Findings of Clozapine Effects on Prepulse Inhibition of Startle: Is It the Route or the Rat?

1998 • 88 citations

Reserpine attenuates d-amphetamine and MDMA-induced transmitter release in vivo: a consideration of dose, core temperature and dopamine synthesis

1998 • 83 citations

Do ? Interactions Regulate Prepulse Inhibition in Rats?

1996 • 78 citations

Potentiation of prepulse inhibition of the startle reflex in rats: pharmacological evaluation of the procedure as a model for detecting antipsychotic activity

1997 • 72 citations

Effects of D3/D2 Dopamine Receptor Agonists and Antagonists on Prepulse Inhibition of Acoustic Startle in the Rat

1995 • 70 citations

Amphetamine releases dopamine from synaptic vesicles by dual mechanisms

1996 • 52 citations

Long‐term clinical and Social outcome studies in schizophrenia in relation to the cognitive and emotional side effects of antipsychotic drugs

1994 • 51 citations

Dopamine agonist-induced hypothermia and disruption of prepulse inhibition: evidence for a role of D3 receptors?

1998 • 48 citations

Prepulses inhibit startle-induced reductions of extracellular dopamine in the nucleus accumbens of rat

1996 • 47 citations

Repeated administration of amphetamine induces sensitisation to its disruptive effect on prepulse inhibition in the rat

1998 • 38 citations

Some, but not all, antipsychotic drugs potentiate a low level of prepulse inhibition shown by rats of the Wistar strain

1997 • 37 citations

Effects of sustained cocaine exposure on sensorimotor gating of startle in rats

1999 • 35 citations

Local pharmacological manipulation of extracellular dopamine levels in the dorsolateral prefrontal cortex and caudate nucleus in the rhesus monkey: An in vivo microdialysis study

1994 • 33 citations

Haloperidol Dose and Blood Level Variability

1995 • 26 citations

Changes in the acoustic startle response and prepulse inhibition of acoustic startle in rats after local injection of pertussis toxin into the ventral tegmental area

1995 • 19 citations

New antipsychotics in schizophrenia: the French experience

1994 • 17 citations

Overcoming the neuroleptic‐induced deficit syndrome: clinical observations with remoxipride

1994 • 14 citations