ANGIOTENSIN II TYPE 1 RECEPTOR ANTAGONIST (LOSARTAN) DOWN-REGULATES TRANSFORMING GROWTH FACTOR-β IN EXPERIMENTAL ACUTE PYELONEPHRITIS

Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells.

1994 • 1,063 citations

Angiotensin II receptors

2019 • 703 citations

Neutralization of TGF-β by Anti-TGF-β Antibody Attenuates Kidney Hypertrophy and the Enhanced Extracellular Matrix Gene Expression in STZ-Induced Diabetic Mice

1996 • 658 citations

Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function.

1993 • 409 citations

TGF-β in kidney fibrosis: A target for gene therapy

1997 • 382 citations

Angiotensin II receptor blockade limits glomerular injury in rats with reduced renal mass.

1992 • 352 citations

Angiotensin II receptor antagonist ameliorates renal tubulointerstitial fibrosis caused by unilateral ureteral obstruction

1995 • 332 citations

Renal Scarring Following Reflux and Nonreflux Pyelonephritis in Children: Evaluation with ^99m Technetium-Dimercaptosuccinic Acid Scintigraphy

1992 • 287 citations

Angiotensin II stimulates the autocrine production of transforming growth factor-β1 in adult rat cardiac fibroblasts

1995 • 256 citations

Targeting TGF-β overexpression in renal disease: Maximizing the antifibrotic action of angiotensin II blockade

1998 • 222 citations

Angiotensin II blockade decreases TGF-β1 and matrix proteins in cyclosporine nephropathy

1997 • 207 citations

Modulation of plasminogen activator inhibitor-1 in vivo: A new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition

1997 • 199 citations

Angiotensin II upregulates type-1 angiotensin II receptors in renal proximal tubule.

1995 • 145 citations

Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice

1996 • 137 citations

Binding characteristics of Escherichia coli adhesins in human urinary bladder

1988 • 132 citations

Analysis of IgA1 O-Glycans in IgA Nephropathy by Fluorophore-Assisted Carbohydrate Electrophoresis

1999 • 128 citations

Insulin and angiotensin II are additive in stimulating TGF-β1 and matrix mRNAs in mesangial cells

1996 • 116 citations

Binding of Escherichia coli S fimbriae to human kidney epithelium

1986 • 109 citations

Etiology of chronic renal failure in Turkish children

1995 • 101 citations

Local cytokine production in a murine model of Escherichia coli pyelonephritis.

1992 • 93 citations

Angiotensin II Receptors

1995 • 92 citations

Will angiotensin II receptor antagonists be renoprotective in humans?

1996 • 87 citations

lnterleukin-6 and lnterleukin-8 in Serum and Urine in Patients with Acute Pyelonephritis in Relation to Bacterial-Virulence-Associated Traits and Renal Function

1994 • 83 citations

Localization of angiotensin AT1 and AT2 receptors.

1999 • 82 citations

Enhancement of tissue plasminogen activator-catalyzed plasminogen activation by Escherichia coli S fimbriae associated with neonatal septicaemia and meningitis.

1991 • 61 citations

Transforming growth factor β1‐mediated inhibition of smooth muscle cell proliferation is associated with a late G1 cell cycle arrest

1993 • 61 citations

Interleukin-6 and interleukin-8 in the urine of children with acute pyelonephritis

1994 • 49 citations

Enhancement of Tissue Plasminogen Activator-Catalyzed Plasminogen Activation by Escherichia coii S Fimbriae Associated with Neonatal Septicaemia and Meningitis

1991 • 46 citations

CYTOKINE GENE EXPRESSION DURING EXPERIMENTAL ESCHERICHIA COLI PYELONEPHRITIS IN MICE

1997 • 46 citations

Penetration of fimbriate enteric bacteria through basement membranes: A hypothesis

1992 • 45 citations

Dissociation between cytokine mRNA expression and protein production in shigellosis

1996 • 30 citations

Pyelonephritis provokes growth retardation and apoptosis in infant rat renal cortex

1997 • 24 citations

Interleukin-1&; and interleukin-6 in the urine, kidney, and bladder of mice inoculated with Escherichia coli

1996 • 19 citations

Localization of angiotensin AT(1) and AT(2) receptors

1999 • 5 citations

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