Identification of slow correlated motions in proteins using residual dipolar and hydrogen-bond scalar couplings

The Energy Landscapes and Motions of Proteins

1991 • 3,100 citations

Direct Measurement of Distances and Angles in Biomolecules by NMR in a Dilute Liquid Crystalline Medium

1997 • 1,695 citations

Protein Structure Prediction and Structural Genomics

2001 • 1,582 citations

A Perspective on Enzyme Catalysis

2003 • 1,191 citations

Enzyme Dynamics During Catalysis

2002 • 710 citations

Simultaneous determination of protein structure and dynamics

2005 • 709 citations

Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactions

1998 • 694 citations

The role of dynamics in allosteric regulation

2003 • 646 citations

NMR structures of biomolecules using field oriented media and residual dipolar couplings

2000 • 441 citations

Collective protein dynamics in relation to function

2000 • 411 citations

Studying excited states of proteins by NMR spectroscopy.

2001 • 382 citations

The Third IgG-Binding Domain from Streptococcal Protein G

1994 • 340 citations

NMR Probes of Molecular Dynamics: Overview and Comparison with Other Techniques

2001 • 338 citations

Evaluation of Backbone Proton Positions and Dynamics in a Small Protein by Liquid Crystal NMR Spectroscopy

2003 • 294 citations

Recent progress in the study of biomolecular structure and dynamics in solution from residual dipolar couplings

2005 • 291 citations

Model-Free Approach to the Dynamic Interpretation of Residual Dipolar Couplings in Globular Proteins

2001 • 280 citations

A novel interactive tool for rigid-body modeling of multi-domain macromolecules using residual dipolar couplings.

2001 • 223 citations

Model-Free Analysis of Protein Backbone Motion from Residual Dipolar Couplings

2002 • 209 citations

Anisotropic Intramolecular Backbone Dynamics of Ubiquitin Characterized by NMR Relaxation and MD Computer Simulation

1998 • 206 citations

Global Efforts in Structural Genomics

2001 • 196 citations

How Much Backbone Motion in Ubiquitin Is Required To Account for Dipolar Coupling Data Measured in Multiple Alignment Media as Assessed by Independent Cross-Validation?

2004 • 195 citations

Structural properties of protein β-sheets

1983 • 193 citations

Correlation between ^3hJ_NC‘ and Hydrogen Bond Length in Proteins

1999 • 153 citations

Amplitudes of Protein Backbone Dynamics and Correlated Motions in a Small α/β Protein: Correspondence of Dipolar Coupling and Heteronuclear Relaxation Measurements

2004 • 136 citations

New approaches to the dynamic interpretation and prediction of NMR relaxation data from proteins

2003 • 131 citations

Characterization of the overall and local dynamics of a protein with intermediate rotational anisotropy: Differentiating between conformational exchange and anisotropic diffusion in the B3 domain of protein G.

2003 • 127 citations

NMR Order Parameters of Biomolecules: A New Analytical Representation and Application to the Gaussian Axial Fluctuation Model

1994 • 123 citations

Structural Dependencies of Interresidue Scalar Coupling ^h3J_NC‘ and Donor ¹H Chemical Shifts in the Hydrogen Bonding Regions of Proteins

2002 • 121 citations

Protein Motions Promote Catalysis

2004 • 117 citations

Locally Anisotropic Internal Polypeptide Backbone Dynamics by NMR Relaxation

1997 • 112 citations

Conformational backbone dynamics of the cyclic decapeptide antamanide. Application of a new multiconformational search algorithm based on NMR data

1993 • 88 citations

Scalar Couplings Across Hydrogen Bonds

2002 • 79 citations

De Novo Determination of Bond Orientations and Order Parameters from Residual Dipolar Couplings with High Accuracy

2003 • 79 citations

Insights into Conformation and Dynamics of Protein GB1 During Folding and Unfolding by NMR

2003 • 78 citations

A systems biology perspective on protein structural dynamics and signal transduction

2005 • 56 citations

Anisotropic Small Amplitude Peptide Plane Dynamics in Proteins from Residual Dipolar Couplings

2004 • 55 citations

Local Dynamic Amplitudes on the Protein Backbone from Dipolar Couplings: Toward the Elucidation of Slower Motions in Biomolecules

2004 • 42 citations

Fluorescence in Situ Hybridization Analysis of Transcript Dynamics in Cells

2001 • 37 citations

Covariation of backbone motion throughout a small protein domain

2003 • 36 citations

High-Accuracy Residual ¹H^N−¹³C and ¹H^N−H^N Dipolar Couplings in Perdeuterated Proteins

2002 • 34 citations

Protein backbone dynamics from N–HN dipolar couplings in partially aligned systems: a comparison of motional models in the presence of structural noise

2005 • 27 citations