How T Cells Count

Tolerance, Danger, and the Extended Family

1994 • 4,654 citations

Serial triggering of many T-cell receptors by a few peptide–MHC complexes

1995 • 1,143 citations

T Cell Activation Determined by T Cell Receptor Number and Tunable Thresholds

1996 • 1,038 citations

Kinetic proofreading in T-cell receptor signal transduction.

1995 • 931 citations

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

1990 • 468 citations

The Repertoire of T Cells Shaped by a Single MHC/Peptide Ligand

1996 • 417 citations

The Minimal Number of Class II MHC-Antigen Complexes Needed for T Cell Activation

1990 • 410 citations

Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis

1991 • 336 citations

Kinetic discrimination in T-cell activation.

1996 • 286 citations

Specificity and flexibility in thymic selection

1994 • 221 citations

Ligand-receptor interactions required for commitment to the activation of the interleukin 2 gene.

1987 • 182 citations

Coexpression of B7-1 and viral (“self”) transgenes in pancreatic β cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes

1995 • 177 citations

Requirements for the simultaneous presence of phorbol esters and calcium ionophores in the expression of human T lymphocyte proliferation-related genes.

1987 • 122 citations

T-cell tolerance and autoimmunity in transgenic models of central and peripheral tolerance

1994 • 64 citations