Potential signalling pathways underlying corticotrophin‐releasing hormone‐mediated neuroprotection from excitotoxicity in rat hippocampus

Localization of novel corticotropin-releasing factor receptor (CRF2) mRNA expression to specific subcortical nuclei in rat brain: comparison with CRF1 receptor mRNA expression

1995 • 917 citations

Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain.

1995 • 836 citations

Neuroprotection by Brain-derived Neurotrophic Factor Is Mediated by Extracellular Signal-regulated Kinase and Phosphatidylinositol 3-Kinase

1999 • 561 citations

BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway.

2000 • 517 citations

Corticotropin-releasing factor receptors are widely distributed within the rat central nervous system: an autoradiographic study

1985 • 474 citations

BDNF Protects the Neonatal Brain from Hypoxic-Ischemic InjuryIn Vivovia the ERK Pathway

2000 • 432 citations

Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor.

1993 • 414 citations

Clinical trials with neuroprotective drugs in acute ischaemic stroke: are we doing the right thing?

1999 • 375 citations

Corticotropin Releasing Factor Decreases Postburst Hyperpolarizations and Excites Hippocampal Neurons

1983 • 310 citations

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP-38) Protects Cerebellar Granule Neurons from Apoptosis by Activating the Mitogen-Activated Protein Kinase (MAP Kinase) Pathway

1997 • 288 citations

Urocortin Protects against Ischemic and Reperfusion Injury via a MAPK-dependent Pathway

2000 • 236 citations

Phosphorylation and Inhibition of Olfactory Adenylyl Cyclase by CaM Kinase II in Neurons

1998 • 184 citations

Arsenite-Induced Apoptosis in Cortical Neurons Is Mediated by c-Jun N-Terminal Protein Kinase 3 and p38 Mitogen-Activated Protein Kinase

2000 • 182 citations

Rat cerebral cortex corticotropin‐releasing hormone receptors: evidence for receptor coupling to multiple G‐proteins

2001 • 139 citations

Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning

1999 • 137 citations

The pro-convulsant actions of corticotropin-releasing hormone in the hippocampus of infant rats

1998 • 119 citations

Corticotropin-Releasing Hormone-Mediated Neuroprotection against Oxidative Stress Is Associated with the Increased Release of Non-amyloidogenic Amyloid β Precursor Protein and with the Suppression of Nuclear Factor-κB

2000 • 116 citations

Characterization of corticotropin‐releasing factor receptor‐mediated adenylate cyclase activity in the rat central nervous system

1987 • 110 citations

Pituitary adenylate cyclase-activating polypeptide protects rat-cultured cortical neurons from glutamate-induced cytotoxicity

1996 • 110 citations

Differential actions of corticotropin releasing factor on basolateral and central amygdaloid neurones, in vitro.

1992 • 108 citations

Developmental profile of messenger RNA for the corticotropin-releasing hormone receptor in the rat limbic system

1996 • 106 citations

Delayed protection by MK-801 and tetrodotoxin in a rat organotypic hippocampal culture model of ischemia.

1994 • 105 citations

Methods to induce primary and secondary traumatic damage in organotypic hippocampal slice cultures

2000 • 102 citations

Protective effect of N-methyl-D-aspartate antagonists after focal cerebral ischemia in rabbits.

1989 • 92 citations

Corticotrophin-releasing factor antagonist inhibits neuronal damage induced by focal cerebral ischaemia or activation of NMDA receptors in the rat brain

1994 • 89 citations

Corticotropin releasing factor antagonist reduces ischemic hippocampal neuronal injury

1991 • 73 citations

Differential regulation of corticotropin-releasing factor1 receptor expression by stress and agonist treatments in brain and cultured cells.

1996 • 68 citations

Evidence for the involvement of corticotrophin‐releasing hormone in the pathogenesis of traumatic brain injury

1998 • 67 citations

Caspase inhibitors are functionally neuroprotective against oxygen glucose deprivation induced CA1 death in rat organotypic hippocampal slices

2000 • 66 citations

Corticotropin-Releasing Hormone-Mediated Neuroprotection against Oxidative Stress Is Associated with the Increased Release of Non-amyloidogenic Amyloid Precursor Protein and with the Suppression of Nuclear Factor- B

2000 • 66 citations

Astressin, a novel and potent CRF antagonist, is neuroprotective in the hippocampus when administered after a seizure

1997 • 59 citations

Neuroprotection by corticotropin releasing factor during hypoxia in rat brain.

1993 • 52 citations

Influence of corticotrophin releasing factor on neuronal cell death in vitro and in vivo

2000 • 28 citations

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