Refolding and reassembly of separate alpha and beta chains of class II molecules of the major histocompatibility complex leads to increased peptide-binding capacity.

Binding of immunogenic peptides to Ia histocompatibility molecules

1985 • 1,209 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

[17] Isolation of microgram quantities of proteins from polyacrylamide gels for amino acid sequence analysis

1983 • 1,115 citations

Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells

1989 • 884 citations

Structural characterization of folding intermediates in cytochrome c by H-exchange labelling and proton NMR

1988 • 823 citations

Mapping the transition state and pathway of protein folding by protein engineering

1989 • 699 citations

Folding and association of proteins

1987 • 697 citations

The Relation Between Major Histocompatibility Complex (MHC) Restriction and the Capacity of Ia to Bind Immunogenic Peptides

1987 • 696 citations

NMR evidence for an early framework intermediate on the folding pathway of ribonuclease A

1988 • 583 citations

Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression.

1981 • 581 citations

Substantial increase of protein stability by multiple disulphide bonds

1989 • 415 citations

Interaction between a "processed" ovalbumin peptide and Ia molecules.

1986 • 247 citations

In vivo competition between self peptides and foreign antigens in T-cell activation

1988 • 216 citations

Is there a single pathway for the folding of a polypeptide chain?

1985 • 200 citations

Identification of classical minor histocompatibility antigen as cell-derived peptide

1990 • 196 citations

Formation of intermolecular disulfide bonds on nascent immunoglobulin polypeptides.

1979 • 147 citations

Toward a better understanding of protein folding pathways.

1988 • 127 citations

A kinetic intermediate in the reaction of an antigenic peptide and I–Ek

1989 • 122 citations

Characterization of a naturally processed MHC class II-restricted T-cell determinant of hen egg lysozyme

1989 • 111 citations

Mutational analysis of a protein-folding pathway

1989 • 111 citations

High-affinity fluorescent peptide binding to I-Ad in lipid membranes.

1986 • 73 citations

Recovery of native conformation of rabbit immunoglobulin G upon recombination of separately renatured heavy and light chains at near-neutral pH

1971 • 67 citations

Disulfide bonds and the translocation of proteins across membranes.

1986 • 53 citations

Role of disulfide bond formation in the folding of human chorionic gonadotropin beta subunit into an alpha beta dimer assembly-competent form.

1990 • 38 citations

Specific binding of antigenic peptides to separate alpha and beta chains of class II molecules of the major histocompatibility complex.

1990 • 32 citations