Attenuation of autoimmune disease and lymphocyte accumulation in MRL/lpr mice by treatment with anti‐Vβ8 antibodies

Murine Models of Systemic Lupus Erythematosus

1985 • 1,572 citations

Lpr and gld: Single Gene Models of Systemic Autoimmunity and Lymphoproliferative Disease

1991 • 1,185 citations

Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

1988 • 940 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms

1989 • 645 citations

A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody

1979 • 506 citations

Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily.

1990 • 430 citations

Differences in Risk of Insulin-Dependent Diabetes in Offspring of Diabetic Mothers and Diabetic Fathers

1984 • 386 citations

Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice.

1980 • 331 citations

Prevention of vaccinia virus infection in imiminodeficient mice by vector-directed IL-2 expression

1987 • 216 citations

Identification of a B cell differentiation factor(s) spontaneously produced by proliferating T cells in murine lupus strains of the lpr/lpr genotype.

1983 • 188 citations

Prevention and treatment of murine experimental allergic encephalomyelitis with T cell receptor V beta-specific antibodies.

1990 • 164 citations

Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/vaccinia recombinant virus

1990 • 140 citations

Evidence for an immunoglobulin-dependent antigen-specific helper T cell.

1977 • 130 citations

Molecular Genetics of Murine Lupus Models

1989 • 129 citations

The fate of CD4-8- T cell receptor-alpha beta+ thymocytes.

1991 • 129 citations

Tolerance-related V beta clonal deletions in normal CD4-8-, TCR-alpha/beta + and abnormal lpr and gld cell populations.

1989 • 127 citations

Phenotype, ontogeny, and repertoire of CD4-CD8- T cell receptor alpha beta + thymocytes. Variable influence of self-antigens on T cell receptor V beta usage.

1991 • 107 citations

Therapy against murine collagen‐induced arthritis with T cell receptor V_β‐specific antibodies

1991 • 102 citations

Clonal diversity and T-cell receptor beta-chain variable gene expression in enlarged lymph nodes of MRL-lpr/lpr lupus mice.

1986 • 96 citations

Junctional region sequences of T-cell receptor beta-chain genes expressed by pathogenic anti-DNA autoantibody-inducing helper T cells from lupus mice: possible selection by cationic autoantigens.

1991 • 90 citations

Immunoregulatory role of maternal idiotypes. Ontogeny of immune networks.

1980 • 82 citations

Establishment of idiotypic helper T-cell repertoires early in life

1985 • 79 citations

Reduction of lupus nephritis in MRL/lpr mice by a bacterial superantigen treatment.

1991 • 75 citations

Internal complementarities in the immune system: regulation of the expression of helper T-cell idiotypes.

1984 • 70 citations

Determinants of IDDM and Perinatal Mortality in Children of Diabetic Mothers

1988 • 65 citations

Idiotype suppression by maternal influence

1977 • 58 citations

V-Region Connectivity in T Cell Repertoires

1989 • 54 citations

Stimulation of human monocytes via CD45, CD44, and LFA-3 triggers macrophage-colony-stimulating factor production. Synergism with lipopolysaccharide and IL-1 beta.

1992 • 53 citations

Suppression of a "recurrent" idiotype results in profound alterations of the whole B-cell compartment.

1981 • 53 citations

T‐Cell Receptor Vβ Repertoire Expression in Murine Models of SLE

1990 • 48 citations

Maternal transmission of idiotypic network interactions selecting available T cell repertoires

1986 • 40 citations

Role of the thymus in murine lupus and cellular transfer of the disease

1982 • 34 citations

Ipr T cells vaccinate against lupus in MRL/lpr mice

1992 • 30 citations

Immune networks. Frequencies of antibody- and idiotype-producing B cell clones in various steady states.

1981 • 29 citations

Turning (Ir gene) low responders into high responders by antibody manipulation of the developing immune system.

1987 • 25 citations

5‐Azacytidine inhibits the lpr gene‐induced lymphadenopathy and acceleration of lupus‐like syndrome in MRL/MpJ‐lpr/lpr mice

1990 • 22 citations

Treatment with IL2/Vaccinia Recombinant Virus Leads to Serologic, Histologic and Phenotypic Normalization of Autoimmune MRL/lpr-lpr Mice

1991 • 18 citations

Selective expansion of idiotype sharing T and B cells in cyclosporin A-mediated autoimmunity

1991 • 6 citations