Synergistic effects of stem cell factor and interleukin 6 or interleukin 11 on the expansion of murine hematopoietic progenitors in liquid suspension culture

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors.

1987 • 847 citations

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium

1990 • 837 citations

Primary structure and functional expression of rat and human stem cell factor DNAs

1990 • 779 citations

Expression and function of c-kit in hemopoietic progenitor cells.

1991 • 756 citations

Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3 and epo to stimulate human progenitor cells of the myeloid and erythroid lineages.

1991 • 454 citations

Ex vivo expansion of enriched peripheral blood CD34+ progenitor cells by stem cell factor, interleukin-1 beta (IL-1 beta), IL-6, IL-3, interferon-gamma, and erythropoietin

1993 • 334 citations

Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule

1991 • 331 citations

Identification in culture of a class of hemopoietic colony-forming units with extensive capability to self-renew and generate multipotential hemopoietic colonies.

1982 • 317 citations

Regulation of very primitive, multipotent, hemopoietic cells by hemopoietin-1

1986 • 283 citations

Role of c-kit ligand in the expansion of human hematopoietic progenitor cells

1992 • 218 citations

Purification and characterization of heterogeneous pluripotent hematopoietic stem cell populations expressing high levels of c-kit receptor

1993 • 185 citations

Synergism of BSF-2/interleukin 6 and interleukin 3 on development of multipotential hemopoietic progenitors in serum-free culture.

1988 • 165 citations

The effect of recombinant mast cell growth factor on purified murine hematopoietic stem cells.

1991 • 157 citations

Mast cell growth factor (c-kit ligand) supports the growth of human multipotential progenitor cells with a high replating potential

1991 • 144 citations

Interleukin 1 plus interleukin 3 plus colony-stimulating factor 1 are essential for clonal proliferation of primitive myeloid bone marrow cells.

1989 • 137 citations

Long-term generation and expansion of human primitive hematopoietic progenitor cells in vitro

1993 • 135 citations

Detection of a human CFC with a high proliferative potential

1989 • 135 citations

Clonal origin of murine hemopoietic colonies with apparent restriction to granuclocyte‐macrophage‐megakaryocyte (GMM) differentiation

1982 • 128 citations

Stage-specific expression of c-kit protein by murine hematopoietic progenitors

1993 • 121 citations

Influence of murine mast cell growth factor (c-kit ligand) on colony formation by mouse marrow hematopoietic progenitor cells.

1991 • 106 citations

Interactions among colony-stimulating factors, IL-1 beta, IL-6, and kit-ligand in the regulation of primitive murine hematopoietic cells.

1992 • 104 citations

Stimulation of murine colony-forming cells with high proliferative potential by the combination of GM-CSF and CSF-1

1988 • 72 citations

Actions of human interleukin-4/B-cell stimulatory factor-1 on proliferation and differentiation of enriched hematopoietic progenitor cells in culture

1990 • 61 citations

Synergistic effects of interleukin-11 with other growth factors on the expansion of murine hematopoietic progenitors and maintenance of stem cells in liquid culture.

1994 • 60 citations

Antigenic analysis of human haemopoietic progenitor cells expressing the growth factor receptor c‐kit

1992 • 59 citations

Synergistic effect of recombinant interferon-gamma and interleukin-3 on the growth of immature human hematopoietic progenitors

1991 • 58 citations

IN VITRO EXPANSION OF THE MURINE PLURIPOTENT HEMOPOIETIC STEM CELL POPULATION IN RESPONSE TO INTERLEUKIN 3 AND INTERLEUKIN 6

1989 • 52 citations

Characterization of hemopoietic cell populations from human cord blood expressing c-kit.

1993 • 47 citations

Human interleukin-4 inhibits proliferation of megakaryocyte progenitor cells in culture

1993 • 38 citations

Synergism of interferon-gamma and stem cell factor on the development of murine hematopoietic progenitors in serum-free culture

1993 • 36 citations

Expression of c-kit mRNA and protein during the differentiation of human hematopoietic progenitor cells.

1993 • 30 citations

Synergistic effects of interleukin-1 beta and interleukin-3 on the expansion of human hematopoietic progenitor cells in liquid cultures

1991 • 27 citations