GISTs with PDGFRA exon 14 mutations represent subset of clinically favorable gastric tumors with epithelioid morphology

Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors

1998 • 4,380 citations

Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal Tumors

2002 • 4,254 citations

PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors

2003 • 2,224 citations

Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor

2003 • 2,216 citations

Gastrointestinal stromal tumors: The incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era

2005 • 1,251 citations

Gastrointestinal Stromal Tumors of the Stomach

2004 • 1,212 citations

Biology of Gastrointestinal Stromal Tumors

2004 • 1,190 citations

KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.

2001 • 964 citations

PDGFRA Mutations in Gastrointestinal Stromal Tumors: Frequency, Spectrum and In Vitro Sensitivity to Imatinib

2005 • 809 citations

Consensus meeting for the management of gastrointestinal stromal tumors Report of the GIST Consensus Conference of 20–21 March 2004, under the auspices of ESMO

2005 • 725 citations

Gain-of-function mutations of platelet-derived growth factor receptor α gene in gastrointestinal stromal tumors

2003 • 665 citations

KIT Extracellular and Kinase Domain Mutations in Gastrointestinal Stromal Tumors

2000 • 648 citations

Mutations in Exon 11 of c-Kit Occur Preferentially in Malignant versus Benign Gastrointestinal Stromal Tumors and Do Not Occur in Leiomyomas or Leiomyosarcomas

1999 • 555 citations

KIT-Negative Gastrointestinal Stromal Tumors

2004 • 478 citations

Signal transduction via the stem cell factor receptor/c-Kit

2004 • 426 citations

Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors.

2003 • 355 citations

Gastrointestinal stromal tumors (GISTs): definition, occurrence, pathology, differential diagnosis and molecular genetics.

2003 • 321 citations

Mutations in Exons 9 and 13 of KIT Gene Are Rare Events in Gastrointestinal Stromal Tumors

2000 • 308 citations

A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential

2004 • 305 citations

Gastrointestinal Stromal Tumors of the Stomach in Children and Young Adults

2005 • 303 citations

Oncogenic protein tyrosine kinases

2004 • 260 citations

Regulation and targets of receptor tyrosine kinases

2002 • 260 citations

Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity

2004 • 215 citations

Gastrointestinal stromal tumors of the stomach.

2004 • 177 citations

Association of Platelet-Derived Growth Factor Receptor α Mutations with Gastric Primary Site and Epithelioid or Mixed Cell Morphology in Gastrointestinal Stromal Tumors

2004 • 164 citations

PDGFRα‐ and c‐kit‐mutated gastrointestinal stromal tumours (GISTs) are characterized by distinctive histological and immunohistochemical features

2005 • 117 citations

Differential expression of KIT/PDGFRA mutant isoforms in epithelioid and mixed variants of gastrointestinal stromal tumors depends predominantly on the tumor site

2004 • 105 citations

KIT 1530ins6 mutation defines a subset of predominantly malignant gastrointestinal stromal tumors of intestinal origin1 1The opinions and assertions contained herein are the expressed views of the authors and are not to be construed as official or reflecting the views of the Departments of the Army or Defense.

2003 • 88 citations

State-of-the Art Therapy for Gastrointestinal Stromal Tumors

2005 • 72 citations

PDGFR expression in differential diagnosis between KIT‐negative gastrointestinal stromal tumours and other primary soft‐tissue tumours of the gastrointestinal tract

2005 • 72 citations