Characterization of Phospholipase C Activity of the Plasma Membrane and Cytosol of an Osteoblast-like Cell Line

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

AN ELECTRON-TRANSPORT SYSTEM ASSOCIATED WITH THE OUTER MEMBRANE OF LIVER MITOCHONDRIA

1967 • 2,311 citations

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

1983 • 1,937 citations

[45] Cytochrome oxidase from beef heart mitochondria

1967 • 1,268 citations

Preparation and properties of plasma membrane and endoplasmic reticulum fragments from isolated rat fat cells

1971 • 838 citations

Diglyceride lipase: a pathway for arachidonate release from human platelets.

1979 • 696 citations

Rapid formation of inositol 1,3,4,5-tetrakisphosphate following muscarinic receptor stimulation of rat cerebral cortical slices

1985 • 641 citations

Hormone-stimulated polyphosphoinositide breakdown in rat liver plasma membranes. Roles of guanine nucleotides and calcium.

1986 • 378 citations

Lipid composition of subcellular particles of human blood platelets

1969 • 337 citations

Receptor-Coupled Activation of Phosphoinositide-Specific Phospholipase C by an N Protein

1986 • 324 citations

Parathyroid hormone-activated calcium channels in an osteoblast-like clonal osteosarcoma cell line. cAMP-dependent and cAMP-independent calcium channels.

1987 • 283 citations

A high affinity calcium-stimulated magnesium-dependent adenosine triphosphatase in rat adipocyte plasma membranes.

1980 • 269 citations

Identification and properties of two distinct phosphatidylinositol-specific phospholipase C enzymes from sheep seminal vesicular glands.

1982 • 248 citations

Stimulation of inositol trisphosphate and diacylglycerol production in renal tubular cells by parathyroid hormone.

1987 • 232 citations

Hydrolysis of polyphosphoinositides by purified sheep seminal vesicle phospholipase C enzymes.

1984 • 225 citations

Nucleotide regulatory protein-mediated activation of phospholipase C in human polymorphonuclear leukocytes is disrupted by phorbol esters.

1987 • 184 citations

Purification of phosphatidylinositol-specific phospholipase C from rat liver.

1981 • 180 citations

A two-receptor model for the action of parathyroid hormone on osteoblasts: A role for intracellular free calcium and cAMP

1985 • 177 citations

The metabolism of tris- and tetraphosphates of inositol by 5-phosphomonoesterase and 3-kinase enzymes.

1987 • 164 citations

Guanosine 5'-O-thiotriphosphate stimulates phospholipase C activity in plasma membranes of rat hepatocytes.

1985 • 154 citations

Parathyroid hormone acutely elevates intracellular calcium in osteoblastlike cells

1987 • 148 citations

Aminoglycoside inhibition of a renal phosphatidylinositol phospholipase C.

1982 • 132 citations

Characterization and properties of a phosphatidylinositol phosphodiesterase (phospholipase C) from platelet cytosol

1979 • 129 citations

Human platelets contain phospholipase C that hydrolyzes polyphosphoinositides.

1983 • 129 citations

Role of calcium and phosphoinositides in the actions of certain hormones and neurotransmitters.

1985 • 122 citations

Alpha 1-adrenergic receptor-mediated phosphoinositide hydrolysis and prostaglandin E2 formation in Madin-Darby canine kidney cells. Possible parallel activation of phospholipase C and phospholipase A2.

1987 • 120 citations

Guanine nucleotides stimulate soluble phosphoinositide-specific phospholipase C in the absence of membranes.

1986 • 116 citations

Thrombin- and nucleotide-activated phosphatidylinositol 4,5-bisphosphate phospholipase C in human platelet membranes.

1987 • 86 citations

Coupling of the thyrotropin-releasing hormone receptor to phospholipase C by a GTP-binding protein distinct from the inhibitory or stimulatory GTP-binding protein.

1986 • 85 citations

Two forms of phosphatidylinositol-specific phospholipase C from bovine brain

1986 • 77 citations

Properties and distribution of phosphatidylinositol-specific phospholipase c in human and horse platelets

1983 • 70 citations

Phosphatidylinositol cleavage catalysed by the soluble fraction from lymphocytes. Activity at pH5.5 and pH7.0

1974 • 70 citations

Phosphatidylinositol-specific Phospholipase C in Fetal Membranes and Uterine Decidua

1981 • 66 citations

Activation of membrane phospholipase C by vasopressin

1986 • 65 citations

The Inhibition and Activation of Ca²⁺‐Dependent Phosphatidylinositol Phosphodiesterase by Phospholipids and Blood Plasma

1980 • 51 citations

Phosphatidylinositol-specific phospholipase C activity of chromaffin granule-binding proteins.

1985 • 39 citations

Possible regulation of phospholipase C activity in human platelets by phosphatidylinositol 4′,5′-bisphosphate

1984 • 35 citations

Phosphatidylinositol hydrolysis and phosphatidylinositol 4′,5′-diphosphate hydrolysis are separable responses during secretagogue action in the rat pancreas

1985 • 20 citations