Exercise and Circadian Rhythm-Induced Variations in Plasma Cortisol Differentially Regulate Interleukin-1β (IL-1β), IL-6, and Tumor Necrosis Factor-α (TNFα) Production in Humans: High Sensitivity of TNFα and Resistance of IL-6

Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

1984 • 3,073 citations

Interleukin-6 and the acute phase response

1990 • 2,740 citations

Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α

1993 • 1,031 citations

Correlations and interactions in the production of interleukin-6 (IL- 6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF

1990 • 991 citations

The production of cytokines by polymorphonuclear neutrophils

1995 • 918 citations

Brain corticosteroid receptor balance and homeostatic control

1991 • 858 citations

Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55

1994 • 799 citations

Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats.

1989 • 723 citations

Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia.

1996 • 522 citations

The Stress Response and the Regulation of Inflammatory Disease

1992 • 469 citations

Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: clinical implications.

1996 • 420 citations

Interaction among hepatocyte-stimulating factors, interleukin 1, and glucocorticoids for regulation of acute phase plasma proteins in human hepatoma (HepG2) cells.

1987 • 358 citations

Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man.

1993 • 289 citations

Elimination of mouse splenic macrophages correlates with increased susceptibility to experimental disseminated candidiasis.

1994 • 251 citations

Circadian variation in disease activity in rheumatoid arthritis.

1982 • 174 citations

Glucocorticoid up-regulation of high-affinity interleukin 6 receptors on human epithelial cells.

1990 • 161 citations

The influence of neuroendocrine pathways on lymphocyte migration

1994 • 157 citations

Hormonal and metabolic responses of untrained, moderately trained, and highly trained men to three exercise intensities

1989 • 149 citations

Protection by alpha 1-acid glycoprotein against tumor necrosis factor-induced lethality.

1994 • 136 citations

Acute glucocorticoid deficiency is associated with plasma elevations of interleukin-6: does the latter participate in the symptomatology of the steroid withdrawal syndrome and adrenal insufficiency?

1996 • 122 citations

BLOOD LEVELS OF 17-HYDROXYCORTICOSTEROIDS FOLLOWING THE ADMINISTRATION OF ADRENAL STEROIDS AND THEIR RELATION TO LEVELS OF CIRCULATING LEUKOCYTES 1

1952 • 121 citations

Glucocorticoids and immune function: physiological relevance and pathogenic potential of hormonal dysfunction

1995 • 120 citations

Selective Depletion of Macrophages Prevents Pituitary-Adrenal Activation in Response to Subpyrogenic, but not to Pyrogenic, Doses of Bacterial Endotoxin in Rats*

1991 • 113 citations

Sequential switching from mu to epsilon via gamma 4 in human B cells stimulated with IL-4 and hydrocortisone.

1993 • 109 citations

Cortisol and immunity

1991 • 106 citations

Changes in corticosteroid sensitivity of peripheral blood lymphocytes after strenuous exercise in humans.

1996 • 99 citations

Acute stress affects cytokines and nitric oxide production by alveolar macrophages differently.

1995 • 81 citations

Evidence for anti-inflammatory effect of normal circulating plasma cortisol.

1986 • 62 citations

Variability of responses across training levels to maximal treadmill exercise

1989 • 51 citations

Exacerbation of Rheumatoid Arthritis after Removal of Adrenal Adenoma in Cushing's Syndrome.

1995 • 43 citations

Hormonal regulation of inflammatory cell cytokine transcript and bioactivity production in response to endotoxin

1992 • 26 citations

Corticotropin-Releasing Hormone (CRH) Stimulation in Nelson''s Syndrome: Response of Adrenocorticotropin Secretion to Pulse Injection and Continuous Infusion of CRH*

1986 • 25 citations

Dissociation between serum interleukin-6 rise and other parameters of disease activity in subacute thyroiditis during treatment with corticosteroid.

1996 • 23 citations

Immunofluorescence of mineralocorticoid receptors in peripheral lymphocytes: Presence of receptor-like activity in patients with the autosomal dominant form of pseudohypoaldosteronism, and its absence in the recessive form

1994 • 12 citations