A zebrafish homologue of the Drosophila neurogenic gene Notch and its pattern of transcription during early embryogenesis

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

CLUSTAL: a package for performing multiple sequence alignment on a microcomputer

1988 • 3,446 citations

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

1991 • 1,693 citations

Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

1985 • 1,063 citations

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

1991 • 770 citations

The choice of cell fate in the epidermis of Drosophila

1991 • 736 citations

Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

1990 • 675 citations

The lin-12 locus specifies cell fates in caenorhabditis elegans

1983 • 598 citations

Cell movements during epiboly and gastrulation in zebrafish

1990 • 552 citations

Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors.

1986 • 427 citations

NF-κB and related proteins: Rel/dorsal homologies meet ankyrin-like repeats

1992 • 415 citations

Mechanisms of neurulation: traditional viewpoint and recent advances

1990 • 392 citations

Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila

1991 • 372 citations

Similarity between cell-cycle genes of budding yeast and fission yeast and the Notch gene of Drosophila

1987 • 366 citations

Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands.

1992 • 354 citations

Notch2: a second mammalian Notch gene

1992 • 346 citations

glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins

1989 • 345 citations

A homolog of Drosophila Notch expressed during mammalian development

1991 • 338 citations

The neurogenic gene Delta of Drosophila melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats

1987 • 317 citations

Xotch , the Xenopus Homolog of Drosophila Notch

1990 • 303 citations

Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function.

1991 • 297 citations

The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch

1988 • 281 citations

Sequence and expression pattern ofpax-6are highly conserved between zebrafish and mice

1992 • 264 citations

Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development

1992 • 253 citations

Delta, a Drosophila neurogenic gene, is transcriptionally complex and encodes a protein related to blood coagulation factors and epidermal growth factor of vertebrates.

1988 • 251 citations

Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells

1992 • 246 citations

A role for the Drosophila neurogenic genes in mesoderm differentiation

1991 • 235 citations

Expression analysis of a Notch homologue in the mouse embryo

1992 • 230 citations

Mutations altering the structure of epidermal growth factor-like coding sequences at the Drosophila Notch locus

1987 • 217 citations

Structure and distribution of the Notch protein in developing Drosophila.

1989 • 208 citations

The yeast SWI4 protein contains a motif present in developmental regulators and is part of a complex involved in cell-cycle-dependent transcription

1989 • 207 citations

The Notch locus of Drosophila melanogaster

1983 • 203 citations

Transcript analysis of glp-1 and lin-12, homologous genes required for cell interactions during development of C. elegans

1989 • 201 citations

The involvement of the Notch locus in Drosophila oogenesis

1992 • 166 citations

Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans

1990 • 157 citations

The embryonic expression of the Notch locus of Drosophila melanogaster and the implications of point mutations in the extracellular EGF-like domain of the predicted protein.

1987 • 157 citations

The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis.

1990 • 153 citations

Genes required for specifying cell fates in Drosophila embryonic sensory nervous system

1990 • 139 citations

Early expression of acetylcholinesterase activity in functionally distinct neurons of the zebrafish

1989 • 126 citations

Neurulation in the anterior trunk region of the zebrafish Brachydanio rerio

1993 • 121 citations

EGF homologous sequences encoded in the genome of Drosophila melanogaster, and their relation to neurogenic genes.

1987 • 116 citations

The timing of early developmental events in Xenopus

1985 • 114 citations

Single amino acid substitutions in EGF-like elements of notch and delta modify drosophila development and affect cell adhesion in vitro

1992 • 113 citations

The Notch locus of Drosophila is required in epidermal cells for epidermal development

1990 • 73 citations

The pattern of transcription of the neurogenic gene Delta of Drosophila melanogaster

1990 • 72 citations

Maternal effects of zygotic mutants affecting early neurogenesis inDrosophila

1982 • 66 citations

Regulatory signals and signal molecules in early neurogenesis of Drosophila melanogaster

1992 • 33 citations