Adaptive changes in 5‐HT_1A receptor‐mediated hippocampal inhibition in the alert rat produced by repeated 8‐OH‐DPAT treatment

5-HT and mechanisms of defence

1991 • 1,017 citations

A G Protein Couples Serotonin and GABA _B Receptors to the Same Channels in Hippocampus

1986 • 870 citations

Pharmacologically distinct actions of serotonin on single pyramidal neurones of the rat hippocampus recorded in vitro.

1987 • 550 citations

8-hydroxy-2-(di-n-propylamino)tetralin, 8-OH-DPAT, a potent and selective simplified ergot congener with central 5-HT-receptor stimulating activity

1982 • 517 citations

Modification of 5‐HT neuron properties by sustained administration of the 5‐HT_1A agonist gepirone: Electrophysiological studies in the rat brain

1987 • 429 citations

Responses of hippocampal pyramidal cells to putative serotonin 5-HT1A and 5-HT1B agonists: A comparative study with dorsal raphe neurons

1988 • 329 citations

Dual serotoninergic projections to forebrain in the rat: Morphologically distinct 5‐HT axon terminals exhibit differential vulnerability to neurotoxic amphetamine derivatives

1991 • 237 citations

Receptor reserve for 5-hydroxytryptamine1A-mediated inhibition of serotonin synthesis: possible relationship to anxiolytic properties of 5-hydroxytryptamine1A agonists.

1990 • 227 citations

Autoradiographic quantification of serotonin_1A receptors in rat brain following antidepressant drug treatment

1989 • 185 citations

Single administration of 5-HT1A agonists decreases 5-HT1A presynaptic, but not postsynaptic receptor-mediated responses: relationship to antidepressant-like action

1987 • 173 citations

5-HT1A receptor ligands in animal models of anxiety, impulsivity and depression: Multiple mechanisms of action?

1993 • 145 citations

Different effects on the responses of functional pre- and postsynaptic 5-HT1A receptors by repeated treatment of rats with the 5-HT1A receptor agonist 8-OH-DPAT

1990 • 135 citations

Alterations of central serotoninergic and dopaminergic neurotransmission in rats chronically treated with ipsapirone: biochemical and electrophysiological studies.

1990 • 131 citations

Differential properties of pre- and postsynaptic 5-hydroxytryptamine1A receptors in the dorsal raphe and hippocampus: I. Effect of spiperone.

1993 • 112 citations

Reversal of helpless behavior in rats by putative 5-HT1A agonists

1988 • 108 citations

Lack of apparent receptor reserve at postsynaptic 5-hydroxytryptamine1A receptors negatively coupled to adenylyl cyclase activity in rat hippocampal membranes.

1992 • 105 citations

Serotonergic innervation of the hippocampus and nucleus accumbens septi and the anxiolytic-like action of midazolam and 5-HT1A a receptor agonists

1993 • 88 citations

Electrophysiological evidence for a large receptor reserve for inhibition of dorsal raphe neuronal firing by 5‐HT_1A agonists

1993 • 87 citations

Tandospirone and its metabolite, 1-(2-pyrimidinyl)-piperazine—I. Effects of acute and long-term administration of tandospirone on serotonin neurotransmission

1991 • 83 citations

Pertussis toxin-sensitive guanine nucleotide-binding protein(S) couple adenosine A1 and 5-hydroxytryptamine1A receptors to the same effector systems in rat hippocampus: biochemical and electrophysiological studies.

1989 • 81 citations

Orthodromic activation of hippocampal CA1 region of the rat

1979 • 75 citations

A single dose of 8-OH-DPAT reduces raphe binding of [3H]8-OH-DPAT and increases the effect of raphe stimulation on 5-HT metabolism

1990 • 67 citations

Intra-hippocampal injection of 8-hydroxy-2(di-n-propylamino)tetralin (8-OH-DPAT) inhibits partial and generalized seizures induced by kindling stimulation in cats

1993 • 60 citations

Effect of acute and repeated administration of 5-HT1A receptor agonists on 5-HT release in rat brain in vivo

1993 • 59 citations

5-HT1A-sensitive adenylyl cyclase of rodent hippocampal neurons: effects of antidepressant treatments and chronic stimulation with agonists.

1991 • 57 citations

Alteration of 5‐HT_1A receptor binding sites following chronic treatment with ipsapirone measured by quantitative autoradiography

1992 • 55 citations

Regulation of 5-hydroxytryptamine1A receptor function in rat hippocampus by short- and long-term administration of 5-hydroxytryptamine1A agonist and antidepressants.

1992 • 55 citations

Anti-conflict efficacy of buspirone following acute versus chronic treatment

1989 • 54 citations

Comparative effects of chronic 8-OH-DPAT, gepirone and ipsapirone treatment on the sensitivity of somatodendritic 5-HT1A autoreceptors

1993 • 52 citations

Desensitization of 5-HT1A autoreceptors by chronic administration of 8-OH-DPAT

1992 • 44 citations

The effect of prolonged treatment with tricyclic antidepressants on the actions of 5-hydroxytryptamine in the hippocampal slice of the rat

1985 • 43 citations

8-OH-DPAT is a strong antagonist of 5-HT action in rat hippocampus

1986 • 40 citations

Electrophysiology of the 5-HT1A ligand MDL 73005EF in the rat hippocampal slice

1991 • 33 citations

Antidepressants: Thirty Years On

1994 • 32 citations

Effect of acute and chronic administration of buspirone on serotonin and benzodiazepine receptor subtypes in the rat brain: An autoradiographic study

1991 • 31 citations

Sustained 5-hydroxytryptamine release-inhibitory and anxiolytic-like action of the partial 5-HT1A receptor agonist, buspirone, after prolonged chronic administration

1993 • 29 citations

Agonist-induced down-regulation of human 5-HT1A and 5-HT2 receptors in Swiss 3T3 cells

1993 • 26 citations

Working memory deficits induced by intrahippocampal administration of 8-OH-DPAT, a 5-HT1A receptor agonist, in the rat

1993 • 24 citations

Pilot study of flesinoxan, a 5‐HT1A agonist, in major depression: Effects on sleep REM latency and body temperature

1993 • 23 citations

Influence of route of administration on potency of the selective 5HT-1A agonist, 8-hydroxy-2-(di-n-propylamino)tetralin, in rats.

1987 • 23 citations

Serotonergic involvement in the inhibitory effects of repeated buspirone treatment on synaptic transmission in the hippocampus

1989 • 22 citations

Actions of 5‐HT₁ ligands on excitatory synaptic transmission in the hippocampus of alert rats

1990 • 19 citations

Pharmacokinetics of buspirone as determined by ex vivo (3H)-DPAT binding

1988 • 13 citations

Single-dose 8-OH-DPAT pretreatment does not Induce tachyphylaxis to the 5-HT release-reducing effect of 5-HT1A autoreceptor agonists

1991 • 13 citations

Use-dependent effects of acute and chronic treatment with imipramine and buspirone on excitatory synaptic transmission in the rat hippocampus in vivo

1993 • 13 citations

Differential effects of centrally‐active antihypertensives on 5‐HT_1A receptors in rat dorso‐lateral septum, rat hippocampus and guinea‐pig hippocampus

1994 • 10 citations