Cloning and Characterization of a Novel Binding Factor (GMEB-2) of the Glucocorticoid Modulatory Element

Basic local alignment search tool

1990 • 87,358 citations

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

The complete genome sequence of the Gram-positive bacterium Bacillus subtilis

1997 • 3,613 citations

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1997 • 2,100 citations

AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian Cancer

1997 • 1,655 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1997 • 1,300 citations

Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene

1987 • 760 citations

RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2

1997 • 585 citations

Glucocorticoid Hormone Action

1979 • 434 citations

The inducible transcription factor NF-κB: structure-function relationship of its protein subunits

1993 • 429 citations

Synergistic action of the glucocorticoid receptor with transcription factors.

1988 • 407 citations

MINIREVIEW: Cyclic AMP Response Element Binding Proteins: A Cornucopia of Transcription Factors

1990 • 394 citations

Phosphorylation of CREB affects its binding to high and low affinity sites: implications for cAMP induced gene transcription.

1992 • 308 citations

In vivo footprinting of rat TAT gene: Dynamic interplay between the glucocorticoid receptor and a liver-specific factor

1991 • 270 citations

Cell-type specific activity of two glucocorticoid responsive units of rat tyrosine aminotransferase gene is associated with multiple binding sites for C/EBP and a novel liver-specific nuclear factor

1991 • 234 citations

Activation of the tyrosine aminotransferase gene is dependent on synergy between liver-specific and hormone-responsive elements.

1993 • 187 citations

A cyclic AMP response element mediates repression of tyrosine aminotransferase gene transcription by the tissue-specific extinguisher locus Tse-1

1990 • 154 citations

DEAF-1, a novel protein that binds an essential region in a Deformed response element.

1996 • 138 citations

Transcription activation of the tyrosine aminotransferase gene by glucocorticoids and cAMP in primary hepatocytes

1987 • 132 citations

Two remote glucocorticoid responsive units interact cooperatively to promote glucocorticoid induction of rat tyrosine aminotransferase gene expression

1989 • 86 citations

Limited proteolysis of covalently labeled glucocorticoid receptors as a probe of receptor structure

1984 • 85 citations

Dissociation of Steroid Binding to Receptors and Steroid Induction of Biological Activity in a Glucocorticoid-Responsive Cell

1983 • 79 citations

Participation of Ets Transcription Factors in the Glucocorticoid Response of the Rat Tyrosine Aminotransferase Gene

1994 • 72 citations

Chromatin structures of the rat tyrosine aminotransferase gene relate to the function of its cis-acting elements.

1990 • 67 citations

Higher levels of control: modulation of steroid hormone-regulated gene transcription.

1992 • 67 citations

Modulation of transcription factor activity by a distant steroid modulatory element.

1992 • 47 citations

The Factor Binding to the Glucocorticoid Modulatory Element of the Tyrosine Aminotransferase Gene Is a Novel and Ubiquitous Heteromeric Complex

1995 • 47 citations

Regulation of Specific Protein Synthesis in Eucaryotic Cells

1970 • 42 citations

Antiglucocorticoid steroids have increased agonist activity in those hepatoma cell lines that are more sensitive to glucocorticoids

1986 • 40 citations

Sequence-selective interactions of transcription factor elements with tandem glucocorticoid-responsive elements at physiological steroid concentrations.

1993 • 37 citations

Modulation of glucocorticoid induction of tyrosine aminotransferase gene expression by variations in cell density.

1992 • 30 citations

Modulation of glucocorticoid induction of stably transfected tyrosine aminotransferase gene constructs involves elements up-stream of the glucocorticoid-responsive element.

1992 • 24 citations

Unlinked Regulation of the Sensitivity of Primary Glucocorticoid-Inducible Responses in Mouse Mammary Tumor Virus Infected Fu5-5 Rat Hepatoma Cells

1988 • 23 citations

A negative tyrosine aminotransferase gene element that blocks glucocorticoid modulatory element-regulated modulation of glucocorticoid-induced gene expression.

1996 • 21 citations

A new cis-acting element involved in tissue-selective glucocorticoid inducibility of tyrosine aminotransferase gene expression.

1993 • 21 citations

Identification of a Novel Transferable cis Element in the Promoter of an Estrogen-Responsive Gene that Modulates Sensitivity to Hormone and Antihormone

1997 • 18 citations

Metal oxyanion stabilization of the rat glucocorticoid receptor is independent of thiols.

1994 • 18 citations

Inverse correlation between dexamethasone 21-mesylate agonist activity and sensitivity to dexamethasone for induction of tyrosine aminotransferase in rat hepatoma cells

1988 • 14 citations

Suppressin: An endogenous negative regulator of immune cell activation

1994 • 11 citations

Selective loss of a DNase I hypersensitive site upstream of the tyrosine aminotransferase gene in mice homozygous for lethal albino deletions.

1992 • 11 citations

Two liver-enriched trans-acting factors support the tissue-specific basal transcription from the rat tyrosine aminotransferase promoter

1992 • 11 citations

Localization of the ∼12 kDa Mr discrepancy in gel migration of the mouse glucocorticoid receptor to the major phosphorylated cyanogen bromide fragment in the transactivating domain

1993 • 11 citations

Negative Regulatory Molecules in the Neuroendocrine and Immune Systems: Suppressin as an Example

1994 • 3 citations