Measurement of thermodynamic nonideality arising from volume-exclusion interactions between proteins and polymers

Analytical ultracentrifugation in biochemistry and polymer science

1995 • 1,970 citations

Studies on gel filtration

1960 • 627 citations

Mechanism of precipitation of proteins by polyethylene glycols. Analysis in terms of excluded volume.

1981 • 555 citations

The effect of volume occupancy upon the thermodynamic activity of proteins: some biochemical consequences

1983 • 503 citations

A New Calibration Procedure for Gel Filtration Columns

1967 • 416 citations

Physical Studies of Lysozyme

1962 • 377 citations

Protein‐solvent interactions

1996 • 374 citations

An approach to the study of phase separation in ternary aqueous systems

1968 • 358 citations

Protein Solvation in Allosteric Regulation: A Water Effect on Hemoglobin

1992 • 338 citations

Solution properties of branched dextrans

1958 • 315 citations

Effect of macromolecular crowding upon the structure and function of an enzyme: glyceraldehyde-3-phosphate dehydrogenase

1981 • 302 citations

The Configuration of the Polyoxyethylene Chain

1965 • 278 citations

Viscosity, sedimentation, and light‐scattering properties of fraction of an acid‐hydrolyzed dextran

1955 • 275 citations

Protein-solvent interactions

2018 • 251 citations

Enzyme Reactions in Polymer Media

1971 • 144 citations

Evaluation of equilibrium constants by affinity chromatography

1974 • 137 citations

Measured change in protein solvation with substrate binding and turnover

1993 • 124 citations

Excluded-volume theory of polymer–protein interactions based on polymer chain statistics

1982 • 119 citations

[40] Purification of ribosomal proteins from Escherichia coli under nondenaturing conditions

1979 • 100 citations

The osmotic behaviour of Sephadex and its effects on chromatography

1968 • 85 citations

Effect of inert polymers on protein self‐association

1981 • 81 citations

Ribosomal Proteins: Their Structure and Spatial Arrangement in Prokaryotic Ribosomes

1984 • 80 citations

Thermodynamic Nonideality in Macromolecular Solutions: Interpretation of Virial Coefficients

1993 • 80 citations

Evidence for protein self-association induced by excluded volume Myoglobin in the presence of globular proteins

1981 • 78 citations

Exponential analysis of concentration or concentration difference data for discrete molecular weight distributions in sedimentation equilibrium

1970 • 57 citations

Layer Technique in Gel Filtration for estimating Differences in the Degree of Dissociation of Closely Related Proteins

1966 • 52 citations

On the application of geometric probability theory to polymer networks and suspensions, I

1990 • 43 citations

Molecular Sieve Studies of Interacting Protein Systems

1968 • 43 citations

Osmometry with single Sephadex beads

1970 • 38 citations

Thermodynamic nonideality in macromolecular solutions

1990 • 37 citations

Self‐association of the pyruvate dehydrogenase complex from Azotobacter vinelandii in the presence of polyethylene glycol

1980 • 33 citations

Reaction boundaries and elution profiles in column chromatography

1967 • 32 citations

Effects of thermodynamic nonideality in kinetic studies

1983 • 29 citations

Simultaneous determination of the individual concentration gradients of two solute species in a centrifuged mixture: Application to analytical ultracentrifugation

1987 • 16 citations

Concentration-dependent migration in gel chromatography of reversibly polymerizing solutes: the osmotic behavior of polyacrylamide gels

1980 • 11 citations

Physical studies on proteins L3 and L24 from the 50 S subunit of the Escherichia coli ribosome

1979 • 10 citations

Evaluation of nonideality from gel chromatographic partition coefficients

1989 • 10 citations

Shapes of proteins L1, L9, L25, and L30 from the 50S subunit of the Escherichia coli ribosome, determined by hydrodynamic studies

1979 • 8 citations

Distribution of polymer chain lengths inside a spherical volume: Solution in terms of a diffusion problem

1984 • 7 citations