Thermodynamic nonideality in macromolecular solutions

Physical chemistry of macromolecules

2007 • 3,839 citations

A theory of gel filtration and its exeperimental verification

1964 • 1,549 citations

Physical Chemistry of Macromolecules.

1962 • 1,093 citations

Studies on gel filtration

1960 • 627 citations

Mechanism of precipitation of proteins by polyethylene glycols. Analysis in terms of excluded volume.

1981 • 555 citations

On the transport of compact particles through solutions of chain-polymers

1973 • 489 citations

24 Bovine Pancreatic Ribonuclease

1971 • 437 citations

Structure of beef liver catalase

1981 • 426 citations

An approach to the study of phase separation in ternary aqueous systems

1968 • 358 citations

Effect of macromolecular crowding upon the structure and function of an enzyme: glyceraldehyde-3-phosphate dehydrogenase

1981 • 302 citations

Viscosity, sedimentation, and light‐scattering properties of fraction of an acid‐hydrolyzed dextran

1955 • 275 citations

The state of tyrosine in egg albumin and in insulin as determined by spectrophotometric titration

1943 • 260 citations

Purification and properties of bovine erythrocyte carbonic anhydrase

1960 • 255 citations

Studies of Chemically Reacting Systems on Sephadex. I. Chromatographic Demonstration of the Gilbert Theory^*

1963 • 207 citations

Reconstitution of Acid-denatured Catalase

1963 • 168 citations

Inter- and Intramolecular Interactions of α-Lactalbumin. I. The Apparent Heterogeneity at Acid pH^*

1964 • 157 citations

An Electrophoretic Study of the Binding of Salt Ions by β-Lactoglobulin and Bovine Serum Albumin.

1949 • 157 citations

Enzyme Reactions in Polymer Media

1971 • 144 citations

The Partial Specific Volumes, in Aqueous Solution, of Three Proteins

1952 • 143 citations

Boundary spreading in sedimentation-velocity experiments. 5. Measurement of the diffusion coefficient of bovine albumin by Fujita's equation

1957 • 138 citations

Dissoziation der Rinderleber-Katalase in ihre Untereinheiten

1967 • 124 citations

Excluded-volume theory of polymer–protein interactions based on polymer chain statistics

1982 • 119 citations

Homnogeneity and the Electrophoretic Behavior of Some Proteins. H. Reversible Spreading and Steady-State Boundary Criteria

1948 • 119 citations

THE INFLUENCE OF pH ON THE MOBILITY AND DIFFUSION OF OVALBUMIN

1941 • 111 citations

The complete amino acid sequence of bovine liver catalase and the partial sequence of bovine erythrocyte catalase

1982 • 111 citations

The indefinite self-association of lysozyme: consideration of composition-dependent activity coefficients

1980 • 100 citations

Effect of inert polymers on protein self‐association

1981 • 81 citations

Treatment of thermodynamic nonideality in equilibrium studies on associating solutes

1975 • 81 citations

Dissociation of Bovine Liver Catalase at Low pH

1962 • 79 citations

Evidence for protein self-association induced by excluded volume Myoglobin in the presence of globular proteins

1981 • 78 citations

The action of urea on the disulphide groups of oxidized glutathione and cystine

1951 • 69 citations

Determination of sedimentation and diffusion constants of horse-radish peroxidase.

1951 • 68 citations

Sedimentation and optical rotation behavior of bovine plasma albumin at low pH in the presence of various anions. Effect of charge on molecular expansion

1957 • 47 citations

Effect of sucrose on the dimerization of α-chymotrypsin allowance for thermodynamic nonideality arising from the presence of a small inert solute

1988 • 46 citations

Ultracentrifugal Characterization of Pepsin and Pepsinogen

1966 • 44 citations

Studies of Free Diffusion in Liquids with the Rayleigh Method. III. The Analysis of Known Mixtures and Some Preliminary Investigations with Proteins

1958 • 44 citations

Molecular Sieve Studies of Interacting Protein Systems

1968 • 43 citations

The study of multiple polymerization equilibria by glass bead exclusion chromatography with allowance for thermodynamic non-ideality effects

1978 • 41 citations

The combination of molecular covolume and frictional coefficient to determine the shape and axial ratio of a rigid macromolecule. Studies on ovalbumin

1977 • 40 citations

Effects of thermodynamic nonideality on protein interactions

1986 • 40 citations

Self‐association of the pyruvate dehydrogenase complex from Azotobacter vinelandii in the presence of polyethylene glycol

1980 • 33 citations

Chromatographic evidence of the self-association of oxyhemoglobin in concentrated solutions: its biological implications

1979 • 33 citations

Physicochemical studies on ovalbumin. 4. Characterization of an iodine-modified derivative by electrophoresis and sedimentation

1962 • 31 citations

Thermodynamic nonideality and the dependence of partition coefficient upon solute concentration in exclusion chromatography

1980 • 30 citations

ON THE MOLECULAR WEIGHT OF CYTOCHROME c FROM MAMMALIAN HEART MUSCLE

1956 • 30 citations

Thermodynamic nonideality as a probe of allosteric mechanisms: Preexistence of the isomerization equilibrium for rabbit muscle pyruvate kinase

1988 • 30 citations

Effects of thermodynamic nonideality in kinetic studies

1983 • 29 citations

Quantitative interpretation of concentration-dependent migration in gel chromatography of reversibly polymerizing solutes.

1975 • 28 citations

Interactions of lens proteins

1983 • 27 citations

Exclusion chromatography of concentrated hemoglobin solutions

1981 • 20 citations

Molecular covolumes of sphere and ellipsoid of revolution combinations

1976 • 19 citations

Thermodynamic nonideality as a probe of macromolecular isomerizations: Application to the acid expansion of bovine serum albumin

1984 • 18 citations

Substrate as a source of thermodynamic nonideality in enzyme kinetic studies: Invertase-catalyzed hydrolysis of sucrose

1988 • 16 citations

Space-filling effects of inert solutes as probes for the detection and study of substrate-mediated conformational changes by enzyme kinetics: Theoretical considerations

1989 • 15 citations

Effect of thermodynamic nonideality in kinetic studies: Evidence for reversible unfolding of urease during urea hydrolysis

1985 • 15 citations

Effects of thermodynamic nonideality on the kinetics of ester hydrolysis by α-chymotrypsin: A model system with preexistence of the isomerization equilibrium

1989 • 15 citations

Thermodynamic nonideality in enzyme catalysis

1989 • 12 citations

Concentration-dependent migration in gel chromatography of reversibly polymerizing solutes: the osmotic behavior of polyacrylamide gels

1980 • 11 citations

Kinetics of multicomponent transport by structured flow in polymer solutions. 7. Polysaccharide-saccharide systems

1985 • 10 citations

Evaluation of nonideality from gel chromatographic partition coefficients

1989 • 10 citations

Distribution of polymer chain lengths inside a spherical volume: Solution in terms of a diffusion problem

1984 • 7 citations

The hydrodynamic properties of the cellodextrin alditols

1976 • 2 citations