Muscle fibers of mdx mice are more vulnerable to exercise than those of normal mice

Dystrophin: The protein product of the duchenne muscular dystrophy locus

1987 • 4,477 citations

X chromosome-linked muscular dystrophy (mdx) in the mouse.

1984 • 1,678 citations

Dystrophin protects the sarcolemma from stresses developed during muscle contraction.

1993 • 1,444 citations

The Molecular Basis of Muscular Dystrophy in the mdx Mouse: a Point Mutation

1989 • 1,171 citations

The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy

1991 • 892 citations

Conversion of mdx myofibres from dystrophin-negative to -positive by injection of normal myoblasts

1989 • 856 citations

Eccentric exercise-induced injury to rat skeletal muscle

1983 • 783 citations

Mechanisms of Exercise-Induced Muscle Fibre Injury

1991 • 576 citations

Exercise-induced muscle damage, repair, and adaptation in humans

1988 • 497 citations

Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice

1988 • 453 citations

Disruptions of muscle fiber plasma membranes. Role in exercise-induced damage.

1992 • 431 citations

Normal dystrophin transcripts detected in Duchenne muscular dystrophy patients after myoblast transplantation

1992 • 429 citations

Acute phase response in exercise. III. Neutrophil and IL-1 beta accumulation in skeletal muscle

1993 • 413 citations

Visualization of Dystrophic Muscle Fibers in Mdx Mouse by Vital Staining with Evans Blue: Evidence of Apoptosis in Dystrophin-Deficient Muscle

1995 • 355 citations

THE mdx MOUSE SKELETAL MUSCLE MYOPATHY: I. A HISTOLOGICAL, MORPHOMETRIC AND BIOCHEMICAL INVESTIGATION

1988 • 343 citations

Results of a Triple Blind Clinical Study of Myoblast Transplantations without Immunosuppressive Treatment in Young Boys with Duchenne Muscular Dystrophy

1993 • 335 citations

Dystrophin abnormalities in Duchenne/Becker muscular dystrophy

1989 • 330 citations

Muscular dystrophy in the mdx mouse: Histopathology of the soleus and extensor digitorum longus muscles

1987 • 282 citations

Eccentric Action of Muscles

1989 • 263 citations

Normal myogenic cells from newborn mice restore normal histology to degenerating muscles of the mdx mouse.

1990 • 241 citations

Invited review: Myoblast transfer: A possible therapy for inherited myopathies?

1991 • 223 citations

Dystrophin-deficient mdx muscle fibers are preferentially vulnerable to necrosis induced by experimental lengthening contractions

1990 • 221 citations

Dystrophin is expressed in mdx skeletal muscle fibers after normal myoblast implantation.

1989 • 216 citations

Muscular Dystrophies—Diseases of the Dystrophin-Glycoprotein Complex

1995 • 204 citations

DUCHENNE MUSCULAR DYSTROPHY

1979 • 200 citations

Molecular and cell biology of skeletal muscle regeneration

1993 • 189 citations

Functional regeneration in the hindlimb skeletal muscle of the mdx mouse

1988 • 179 citations

FURTHER OBSERVATIONS ON THE PATHOLOGICAL RESPONSES OF RAT SKELETAL MUSCLE TO TOXINS ISOLATED FROM THE VENOM OF THE AUSTRALIAN TIGER SNAKE, NOTECHIS SCUTATUS SCUTATUS

1978 • 163 citations

High efficiency of muscle regeneration after human myoblast clone transplantation in SCID mice.

1994 • 160 citations

Effect of training on eccentric exercise-induced muscle damage

1993 • 150 citations

Lesions in the rat soleus muscle following eccentrically biased exercise

1988 • 144 citations

Evidence ofmdx mouse skeletal muscle fragility in vivo by eccentric running exercise

1998 • 121 citations

Contractile properties and susceptibility to exercise-induced damage of normal and mdx mouse tibialis anterior muscle

1992 • 116 citations

Ultrastructure of the skeletal muscle in the X chromosome-linked dystrophic (mdx) mouse

1988 • 112 citations

Control of inflammatory damage by anti-LFA-l: Increase success of myoblast transplantation

1997 • 106 citations

Human myoblast transplantation in immunodeficient and immunosuppressed mice: Evidence of rejection

1994 • 99 citations

Myoblast Transplantation in Monkeys: Control of Immune Response by FK506

1996 • 93 citations

Successful histocompatible myoblast transplantation in dystrophin-deficient mdx mouse despite the production of antibodies against dystrophin.

1995 • 88 citations

Age‐related differences in regeneration of dystrophic (mdx) and normal muscle in the mouse

1995 • 87 citations

How does dystrophin deficiency lead to muscle degeneration? — Evidence from the MDX mouse

1995 • 86 citations

Molecular and Cell Biology of Muscular Dystrophy

1993 • 69 citations

Effects of contractile activity on muscle damage in the dystrophin-deficient mdx mouse

1991 • 60 citations

ROLE OF MECHANICAL DAMAGE IN PATHOGENESIS OF PROXIMAL MYOPATHY IN MAN

1984 • 60 citations

Utilization of myoblasts from transgenic mice to evaluate the efficacy of myoblast transplantation

1994 • 55 citations

Effect of eccentric exercise on plasma enzyme activities previously elevated by eccentric exercise

1994 • 45 citations

Dystrophic changes in mdx muscle regenerating from denervation and devascularization

1991 • 44 citations

Use of fluorescent latex microspheres (FLMs) to follow the fate of transplanted myoblasts.

1993 • 38 citations

Cyclophosphamide immunosuppression does not permit successful myoblast allotransplantation in mouse

1995 • 33 citations

Control of Inflammatory Damage by Anti-Lfa-1: Increase Success of Myoblast Transplantation

1997 • 32 citations

Effect of eccentric exercise on natural killer cell activity

1995 • 24 citations